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WormBase Tree Display for Gene: WBGene00000196

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Name Class

WBGene00000196SMapS_parentSequenceW02B12
IdentityVersion2
NameCGC_nameaars-1Person_evidenceWBPerson36
WBPerson10953
Sequence_nameW02B12.6
Molecular_nameW02B12.6a
W02B12.6a.1
CE28096
W02B12.6b
Other_namealasAccession_evidenceEMBLAF188715
ars-1
CELE_W02B12.6Accession_evidenceNDBBX284602
Public_nameaars-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
229 Jan 2010 14:16:16WBPerson2970Name_changeCGC_nameaars-1
Other_namears-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classaars
Allele (86)
RNASeq_FPKM (74)
GO_annotation (27)
Ortholog (27)
ParalogWBGene00000197Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionars-1 encodes an alanyl tRNA synthetase; on the basis of similarity to S. cerevisiae ALA1p, ARS-1 is probably cytoplasmic.Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable alanine-tRNA ligase activity and aminoacyl-tRNA editing activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 8 and progressive leukoencephalopathy with ovarian failure. Is an ortholog of human AARS2 (alanyl-tRNA synthetase 2, mitochondrial).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111479Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21022)
DOID:0070396Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21022)
Molecular_infoCorresponding_CDSW02B12.6a
Corresponding_CDS_historyW02B12.6:wp52
Corresponding_transcriptW02B12.6b
W02B12.6a.1
Other_sequence (13)
Associated_featureWBsf650578
WBsf650579
WBsf666140
WBsf666141
WBsf989766
WBsf989767
WBsf989768
WBsf223938
Experimental_infoRNAi_resultWBRNAi00036174Inferred_automaticallyRNAi_primary
WBRNAi00019490Inferred_automaticallyRNAi_primary
WBRNAi00054558Inferred_automaticallyRNAi_primary
WBRNAi00097773Inferred_automaticallyRNAi_primary
WBRNAi00027491Inferred_automaticallyRNAi_primary
WBRNAi00093116Inferred_automaticallyRNAi_primary
WBRNAi00071225Inferred_automaticallyRNAi_primary
WBRNAi00026453Inferred_automaticallyRNAi_primary
Expr_patternExpr1023414
Expr1030115
Expr1158107
Expr2009062
Expr2027298
Microarray_results (21)
Expression_cluster (105)
Interaction (51)
Map_infoMapIIPosition3.47821Error0.002605
PositivePositive_cloneW02B12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00014089
WBPaper00038491
WBPaper00055090
WBPaper00065116
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene