WormBase Tree Display for Gene: WBGene00000229
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WBGene00000229 | SMap | S_parent | Sequence | C34E10 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | atp | ||||||
Allele (29) | |||||||
Strain | WBStrain00006141 | ||||||
WBStrain00001205 | |||||||
WBStrain00024104 | |||||||
WBStrain00024105 | |||||||
WBStrain00037206 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (53) | |||||||
Contained_in_operon | CEOP3268 | ||||||
Ortholog (35) | |||||||
Paralog | WBGene00004959 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00006921 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00010419 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00012040 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00013025 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | atp-2 encodes the beta subunit of the soluble, catalytic F1 portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V); atp-2 activity is required for embryonic and larval development past the L3 stage, as well as for normal mobility, pharyngeal pumping, defecation, growth rate, and larval lifespan; in males, atp-2 activity is also required cell autonomously in male-specific sensory neurons for response to hermaphrodite contact, the first step in a series of stereotypical male mating behaviors; in vitro, the N-terminus of ATP-2 interacts directly with the conserved PLAT domains of human polycystin (PC)-1 and C. elegans LOV-1, which is expressed exclusively in adult male sensory neurons and is also required for the response to hermaphrodite contact; atp-2 is widely expressed throughout development in both sexes; ATP-2 localizes to mitochondria and to cilia of male-specific neurons; in the male-specific CEM neurons ATP-2 colocalizes with PKD-2, the C. elegans homolog of human polycystin (PC)-2. | Paper_evidence | WBPaper00004403 | |||
WBPaper00004813 | |||||||
WBPaper00024944 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 16 Jan 2007 00:00:00 | ||||||
Automated_description | Enables protein domain specific binding activity. Involved in several processes, including determination of adult lifespan; inductive cell migration; and pharyngeal pumping. Located in mitochondrion and non-motile cilium. Expressed in HOB; head; ray neuron type B; and tail. Is an ortholog of human ATP5F1B (ATP synthase F1 subunit beta). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C34E10.6 | |||||
Corresponding_transcript | C34E10.6.1 | ||||||
C34E10.6.2 | |||||||
Other_sequence (447) | |||||||
Associated_feature (19) | |||||||
Experimental_info (11) | |||||||
Map_info | Map | III | Position | -1.91727 | Error | 0.020951 | |
Positive | Positive_clone | C34E10 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4167 | |||||
4513 | |||||||
Pseudo_map_position | |||||||
Reference (48) | |||||||
Remark (2) | |||||||
Method | Gene |