Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00000231

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00000231EvidenceCGC_data_submission
SMapS_parentSequenceD2045
IdentityVersion1
NameCGC_nameatx-2
Sequence_nameD2045.1
Molecular_name (12)
Other_nameCELE_D2045.1Accession_evidenceNDBBX284603
Public_nameatx-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classatx
Allele (108)
StrainWBStrain00007402
RNASeq_FPKM (74)
GO_annotation (78)
Ortholog (35)
Structured_descriptionConcise_descriptionatx-2 is required for early embryonic patterning; it encodes an ortholog of human ataxin-2.Paper_evidenceWBPaper00004103
WBPaper00004612
WBPaper00005068
WBPaper00012788
WBPaper00012830
WBPaper00012882
WBPaper00012897
WBPaper00013003
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable mRNA binding activity. Involved in several processes, including gamete generation; positive regulation of reproductive process; and regulation of cell cycle. Located in cytoplasm. Expressed in body wall musculature; dorsal nerve cord; germ line; gonad; and ventral nerve cord. Used to study autosomal dominant cerebellar ataxia. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Is an ortholog of human ATXN2 (ataxin 2) and ATXN2L (ataxin 2 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:1441Homo sapiensPaper_evidenceWBPaper00024364
Curator_confirmedWBPerson324
Date_last_updated02 Aug 2013 00:00:00
Potential_modelDOID:0050955Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10555)
DOID:0060892Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10555)
Disease_relevanceHuman Ataxin2 (ATXN2) contains a polygutamine tract, long expansions of which cause spinocerebellar ataxia-2.Homo sapiensPaper_evidenceWBPaper00024364
Accession_evidenceOMIM183090
601517
Curator_confirmedWBPerson324
Date_last_updated02 Aug 2013 00:00:00
Models_disease_in_annotationWBDOannot00000221
Molecular_infoCorresponding_CDSD2045.1a
D2045.1b
D2045.1c
D2045.1d
Corresponding_CDS_historyD2045.1:wp132
D2045.1:wp138
D2045.1a:wp275
D2045.1b:wp275
D2045.1c:wp275
D2045.1d:wp275
Corresponding_transcriptD2045.1a.1
D2045.1b.1
D2045.1c.1
D2045.1d.1
Other_sequence (12)
Associated_feature (16)
Experimental_infoRNAi_resultWBRNAi00112057Inferred_automaticallyRNAi_primary
WBRNAi00091001Inferred_automaticallyRNAi_primary
WBRNAi00062721Inferred_automaticallyRNAi_primary
WBRNAi00062713Inferred_automaticallyRNAi_primary
WBRNAi00064292Inferred_automaticallyRNAi_primary
WBRNAi00008579Inferred_automaticallyRNAi_primary
WBRNAi00064291Inferred_automaticallyRNAi_primary
WBRNAi00062707Inferred_automaticallyRNAi_primary
WBRNAi00068316Inferred_automaticallyRNAi_primary
WBRNAi00043480Inferred_automaticallyRNAi_primary
WBRNAi00024959Inferred_automaticallyRNAi_primary
WBRNAi00064290Inferred_automaticallyRNAi_primary
WBRNAi00068317Inferred_automaticallyRNAi_primary
WBRNAi00006170Inferred_automaticallyRNAi_primary
WBRNAi00002739Inferred_automaticallyRNAi_primary
WBRNAi00065646Inferred_automaticallyRNAi_primary
WBRNAi00062715Inferred_automaticallyRNAi_primary
WBRNAi00002575Inferred_automaticallyRNAi_primary
WBRNAi00064286Inferred_automaticallyRNAi_primary
WBRNAi00068829Inferred_automaticallyRNAi_primary
WBRNAi00080505Inferred_automaticallyRNAi_primary
WBRNAi00062712Inferred_automaticallyRNAi_primary
WBRNAi00062717Inferred_automaticallyRNAi_primary
WBRNAi00112232Inferred_automaticallyRNAi_primary
WBRNAi00068313Inferred_automaticallyRNAi_primary
WBRNAi00043479Inferred_automaticallyRNAi_primary
WBRNAi00062720Inferred_automaticallyRNAi_primary
WBRNAi00062718Inferred_automaticallyRNAi_primary
WBRNAi00112059Inferred_automaticallyRNAi_primary
WBRNAi00085627Inferred_automaticallyRNAi_primary
WBRNAi00068315Inferred_automaticallyRNAi_primary
WBRNAi00007270Inferred_automaticallyRNAi_primary
WBRNAi00062714Inferred_automaticallyRNAi_primary
WBRNAi00062719Inferred_automaticallyRNAi_primary
WBRNAi00062708Inferred_automaticallyRNAi_primary
WBRNAi00112060Inferred_automaticallyRNAi_primary
WBRNAi00062710Inferred_automaticallyRNAi_primary
WBRNAi00064289Inferred_automaticallyRNAi_primary
WBRNAi00062709Inferred_automaticallyRNAi_primary
WBRNAi00064285Inferred_automaticallyRNAi_primary
WBRNAi00043482Inferred_automaticallyRNAi_primary
WBRNAi00068314Inferred_automaticallyRNAi_primary
WBRNAi00112058Inferred_automaticallyRNAi_primary
WBRNAi00062711Inferred_automaticallyRNAi_primary
WBRNAi00064288Inferred_automaticallyRNAi_primary
WBRNAi00062716Inferred_automaticallyRNAi_primary
Expr_pattern (12)
Drives_constructWBCnstr00000337
WBCnstr00013308
WBCnstr00037643
WBCnstr00039983
Construct_productWBCnstr00037643
WBCnstr00039241
WBCnstr00039983
AntibodyWBAntibody00000787
WBAntibody00000788
Microarray_results (29)
Expression_cluster (120)
Interaction (198)
Map_infoMapIIIPosition2.51032Error0.003566
PositivePositive_cloneD2045Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (44)
RemarkSequence connection from [Kiehl TR]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene