WormBase Tree Display for Gene: WBGene00000262
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| WBGene00000262 | SMap | S_parent | Sequence | F54B11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | bra-1 | Paper_evidence | WBPaper00004784 | |||||
| Sequence_name | F54B11.6 | ||||||||
| Molecular_name | F54B11.6 | ||||||||
| F54B11.6.1 | |||||||||
| CE05930 | |||||||||
| Other_name | CELE_F54B11.6 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | bra-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 06 May 2005 13:20:55 | WBPerson2970 | Event | Acquires_merge | WBGene00010029 | ||||
| Acquires_merge | WBGene00010029 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | bra | ||||||||
| Allele (45) | |||||||||
| Strain | WBStrain00029113 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00068933 | ||||||||
| 00068934 | |||||||||
| 00068935 | |||||||||
| 00068936 | |||||||||
| 00068937 | |||||||||
| 00068938 | |||||||||
| 00068939 | |||||||||
| 00068940 | |||||||||
| 00107131 | |||||||||
| 00107132 | |||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00017757 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | bra-1 is an ortholog of human ZMYND11 (zinc finger MYND-type containing 11) and ZMYND8 (zinc finger MYND-type containing 8); bra-1 is involved in negative regulation of transforming growth factor beta receptor signaling pathway, and its activity is required for normal adult lifespan; bra-1 exhibits receptor binding activity; bra-1 is expressed in the nervous system; bra-1 is localized to the axon and the dendrite. | Paper_evidence | WBPaper00004784 | |||||
| WBPaper00031040 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 10 Apr 2017 00:00:00 | ||||||||
| Automated_description | Enables signaling receptor binding activity. Involved in determination of adult lifespan and negative regulation of transforming growth factor beta receptor signaling pathway. Located in axon and dendrite. Expressed in neurons. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 30 and stomach cancer. Is an ortholog of human ZMYND11 (zinc finger MYND-type containing 11). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070060 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16966) | ||||
| DOID:10534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16966) | ||||||
| Molecular_info | Corresponding_CDS | F54B11.6 | |||||||
| Corresponding_transcript | F54B11.6.1 | ||||||||
| Other_sequence | RSC01641_1 | ||||||||
| RS07208 | |||||||||
| CR02234 | |||||||||
| HGC12281_1 | |||||||||
| HG05404 | |||||||||
| CBC10296_1 | |||||||||
| CRC01546_1 | |||||||||
| CR04017 | |||||||||
| Associated_feature | WBsf648684 | ||||||||
| WBsf655221 | |||||||||
| WBsf655222 | |||||||||
| WBsf1007660 | |||||||||
| WBsf1007661 | |||||||||
| WBsf1024261 | |||||||||
| WBsf236589 | |||||||||
| WBsf236590 | |||||||||
| WBsf236591 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00015569 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000661 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00068013 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032738 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048224 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1630 | ||||||||
| Expr1646 | |||||||||
| Expr1012640 | |||||||||
| Expr1030168 | |||||||||
| Expr1152029 | |||||||||
| Expr2009645 | |||||||||
| Expr2027884 | |||||||||
| Drives_construct | WBCnstr00000292 | ||||||||
| WBCnstr00000293 | |||||||||
| WBCnstr00037621 | |||||||||
| Construct_product | WBCnstr00037621 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (161) | |||||||||
| Interaction (34) | |||||||||
| WBProcess | WBbiopr:00000025 | ||||||||
| Map_info | Map | X | Position | 13.8751 | Error | 0.042607 | |||
| Positive | Positive_clone | F54B11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5276 | |||||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | This Locus was previously connected to F54B11.1 but this connection may have been an error and has been removed. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
