WormBase Tree Display for Gene: WBGene00000366
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| WBGene00000366 | SMap | S_parent | Sequence | R10E11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cbp-1 | Person_evidence | WBPerson419 | |||||
| Sequence_name | R10E11.1 | ||||||||
| Molecular_name | R10E11.1a | ||||||||
| R10E11.1a.1 | |||||||||
| CE47039 | |||||||||
| R10E11.1b | |||||||||
| CE46860 | |||||||||
| R10E11.1c | |||||||||
| CE46909 | |||||||||
| R10E11.1a.2 | |||||||||
| R10E11.1b.1 | |||||||||
| R10E11.1c.1 | |||||||||
| Other_name | cep-1 | ||||||||
| CBD | Paper_evidence | WBPaper00044307 | |||||||
| CELE_R10E11.1 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | cbp-1 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cbp | ||||||||
| Allele | WBVar00275434 | ||||||||
| WBVar00275433 | |||||||||
| WBVar01500260 | |||||||||
| WBVar01267267 | |||||||||
| WBVar01267268 | |||||||||
| WBVar01267270 | |||||||||
| WBVar01480216 | |||||||||
| WBVar01480217 | |||||||||
| WBVar00000458 | |||||||||
| WBVar00000459 | |||||||||
| WBVar02049721 | |||||||||
| WBVar01499774 | |||||||||
| WBVar01567199 | |||||||||
| WBVar00852400 | |||||||||
| WBVar00852401 | |||||||||
| WBVar00852402 | |||||||||
| WBVar00178140 | |||||||||
| WBVar00178141 | |||||||||
| WBVar00852403 | |||||||||
| WBVar00178142 | |||||||||
| WBVar00852404 | |||||||||
| WBVar00852405 | |||||||||
| WBVar00852406 | |||||||||
| WBVar00852407 | |||||||||
| WBVar00852408 | |||||||||
| WBVar00852409 | |||||||||
| WBVar00852410 | |||||||||
| WBVar02144164 | |||||||||
| WBVar00852411 | |||||||||
| WBVar00852412 | |||||||||
| WBVar00852413 | |||||||||
| WBVar00852414 | |||||||||
| WBVar00852415 | |||||||||
| WBVar00852416 | |||||||||
| WBVar00852417 | |||||||||
| WBVar00852418 | |||||||||
| WBVar00852419 | |||||||||
| WBVar00852420 | |||||||||
| WBVar00852421 | |||||||||
| WBVar00852422 | |||||||||
| WBVar00852423 | |||||||||
| WBVar00852424 | |||||||||
| WBVar00852425 | |||||||||
| WBVar00852426 | |||||||||
| WBVar00852427 | |||||||||
| WBVar00092702 | |||||||||
| WBVar00852428 | |||||||||
| WBVar00852429 | |||||||||
| WBVar00852430 | |||||||||
| WBVar00852431 | |||||||||
| WBVar00852432 | |||||||||
| WBVar00852433 | |||||||||
| WBVar00852434 | |||||||||
| WBVar00852435 | |||||||||
| WBVar00852436 | |||||||||
| WBVar00564728 | |||||||||
| WBVar00852437 | |||||||||
| WBVar00852438 | |||||||||
| WBVar00852439 | |||||||||
| WBVar00852440 | |||||||||
| WBVar00852441 | |||||||||
| WBVar00852442 | |||||||||
| WBVar01793444 | |||||||||
| WBVar00852443 | |||||||||
| WBVar00852444 | |||||||||
| WBVar00852445 | |||||||||
| WBVar00852446 | |||||||||
| WBVar00852447 | |||||||||
| WBVar00852448 | |||||||||
| WBVar00852449 | |||||||||
| WBVar00852450 | |||||||||
| WBVar00852451 | |||||||||
| WBVar00852452 | |||||||||
| WBVar00852453 | |||||||||
| WBVar00852454 | |||||||||
| WBVar00852455 | |||||||||
| WBVar00602767 | |||||||||
| WBVar00852456 | |||||||||
| WBVar00852457 | |||||||||
| WBVar00852458 | |||||||||
| WBVar00852459 | |||||||||
| WBVar00852460 | |||||||||
| WBVar00852461 | |||||||||
| WBVar00852462 | |||||||||
| WBVar02132547 | |||||||||
| WBVar01397195 | |||||||||
| WBVar01447669 | |||||||||
| WBVar00405993 | |||||||||
| WBVar01447670 | |||||||||
| WBVar00405994 | |||||||||
| WBVar00405995 | |||||||||
| WBVar00405996 | |||||||||
| WBVar00405997 | |||||||||
| WBVar00405998 | |||||||||
| WBVar00405999 | |||||||||
| WBVar00406000 | |||||||||
| WBVar00406001 | |||||||||
| WBVar00088352 | |||||||||
| WBVar00406002 | |||||||||
| WBVar00406003 | |||||||||
| WBVar00406004 | |||||||||
| WBVar00406005 | |||||||||
| WBVar00406006 | |||||||||
| WBVar00406007 | |||||||||
| WBVar00406008 | |||||||||
| WBVar00406009 | |||||||||
| WBVar01332247 | |||||||||
| WBVar00406010 | |||||||||
| WBVar00406011 | |||||||||
| WBVar01492875 | |||||||||
| WBVar00406012 | |||||||||
| WBVar00406013 | |||||||||
| WBVar00406014 | |||||||||
| WBVar00406015 | |||||||||
| WBVar00406016 | |||||||||
| WBVar00406017 | |||||||||
| WBVar00406018 | |||||||||
| WBVar00100944 | |||||||||
| WBVar00406019 | |||||||||
| WBVar00406020 | |||||||||
| Legacy_information | [Mello C] cbp for CBP/p300 related gene. No mutants known. Predicted gene R10E11.1 | ||||||||
| Strain | WBStrain00002432 | ||||||||
| WBStrain00002490 | |||||||||
| WBStrain00040750 | |||||||||
| WBStrain00026532 | |||||||||
| WBStrain00036243 | |||||||||
| WBStrain00040749 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (41) | |||||||||
| Ortholog (42) | |||||||||
| Paralog | WBGene00010545 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00016220 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00009595 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00016221 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00008209 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | cbp-1 encodes a homolog of the mammalian transcriptional cofactors CBP (OMIM:600140) and p300 (E1A-BINDING PROTEIN, 300-KD; OMIM:602700) that have been shown to possess histone acetyltransferase activity, and which, when mutated, lead to Rubinstein-Taybi syndrome (OMIM:180849) and colorectal cancer (OMIM:114500); at least one splicing form of CBP-1 exhibits histone acetyltransferase (HAT) activity in vitro and has a glutamine/asparagine-rich domain; CBP-1 is required during embryogenesis for differentiation of all non-neuronal somatic cell types; CBP-1 is expressed very early in embryogenesis, suggesting that it may interact with maternally provided transcription factors, such as SKN-1, to specific developmental fates. | Paper_evidence | WBPaper00003050 | |||||
| WBPaper00005068 | |||||||||
| WBPaper00005101 | |||||||||
| WBPaper00005137 | |||||||||
| WBPaper00012788 | |||||||||
| WBPaper00012830 | |||||||||
| WBPaper00012882 | |||||||||
| WBPaper00012897 | |||||||||
| WBPaper00013003 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; histone acetyltransferase activity; and lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Involved in several processes, including positive regulation of transcription by RNA polymerase II; regulation of distal tip cell migration; and spermatogenesis. Located in cytoplasm and nucleus. Expressed in alimentary system; distal tip cell; head; and tail. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Huntington's disease; Rubinstein-Taybi syndrome; and leukemia (multiple). Is an ortholog of human CREBBP (CREB binding protein). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (16) | ||||||||
| Modifies_disease | DOID:10652 | ||||||||
| Modifies_disease_in_annotation | WBDOannot00001083 | ||||||||
| Molecular_info | Corresponding_CDS | R10E11.1a | |||||||
| R10E11.1b | |||||||||
| R10E11.1c | |||||||||
| Corresponding_CDS_history | R10E11.1a:wp229 | ||||||||
| R10E11.1b:wp229 | |||||||||
| R10E11.1c:wp229 | |||||||||
| Corresponding_transcript | R10E11.1a.1 | ||||||||
| R10E11.1a.2 | |||||||||
| R10E11.1b.1 | |||||||||
| R10E11.1c.1 | |||||||||
| Other_sequence (42) | |||||||||
| Associated_feature (17) | |||||||||
| Transcription_factor | WBTranscriptionFactor000427 | ||||||||
| Experimental_info | RNAi_result (128) | ||||||||
| Expr_pattern (14) | |||||||||
| Drives_construct | WBCnstr00003040 | ||||||||
| WBCnstr00003080 | |||||||||
| WBCnstr00004515 | |||||||||
| WBCnstr00004534 | |||||||||
| WBCnstr00005915 | |||||||||
| WBCnstr00005916 | |||||||||
| WBCnstr00019390 | |||||||||
| Construct_product | WBCnstr00005915 | ||||||||
| WBCnstr00005916 | |||||||||
| WBCnstr00040741 | |||||||||
| Antibody | WBAntibody00000452 | ||||||||
| WBAntibody00000453 | |||||||||
| WBAntibody00002112 | |||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (147) | |||||||||
| Interaction (302) | |||||||||
| WBProcess | WBbiopr:00000070 | ||||||||
| Map_info | Map | III | Position | 0.996159 | Error | 0.002046 | |||
| Positive | Positive_clone | R10E11 | Person_evidence | WBPerson419 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4177 | |||||||
| 4195 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (200) | |||||||||
| Picture | WBPicture0000013084 | ||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| cep-1 has been used as an unapproved name for what is the CGC approved cbp-1 (R10E11.1). The real CGC approved cep-1 (F52B5.5) is a p53 homolog, whereas the approved cbp-1 is a p300 homolog | Paper_evidence | WBPaper00004757 | |||||||
| Method | Gene |
