Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00000422

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00000422EvidenceCGC_data_submission
SMapS_parentSequenceF08F1
IdentityVersion1
NameCGC_nameced-8Person_evidenceWBPerson261
Sequence_nameF08F1.5
Molecular_nameF08F1.5
F08F1.5.1
CE34294
Other_nameCELE_F08F1.5Accession_evidenceNDBBX284606
Public_nameced-8
DB_infoDatabaseAceViewgeneXJ34
WormQTLgeneWBGene00000422
WormFluxgeneWBGene00000422
NDBlocus_tagCELE_F08F1.5
PanthergeneCAEEL|WormBase=WBGene00000422|UniProtKB=O17386
familyPTHR16024
NCBIgene184190
RefSeqproteinNM_077026.10
SwissProtUniProtAccO17386
TREEFAMTREEFAM_IDTF316454
UniProt_GCRPUniProtAccO17386
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classced
Allele (64)
Legacy_information[C.elegansII] n1891 : programmed cell deaths abnormal and protracted; dying cells arrest at highly refractile stage; killer cells fail to engulf target cells; superficially resembles engulfment group A (ced-1,6,7); but synergizes with weak ced-3 alleles in preventing cell death; no gross phenotype. OA3: n1999, n2090, n2093. Cloned: encodes predicted novel protein. [Ellis et al. 1991; MT]
StrainWBStrain00027186
WBStrain00027187
WBStrain00037401
RNASeq_FPKM (74)
GO_annotation (32)
Ortholog (52)
Structured_descriptionConcise_descriptionThe ced-8 gene encodes a homolog of the human putative membrane transporter XK; ced-8 is required for apoptosis to occur with normal speed during embryonic development.Paper_evidenceWBPaper00003983
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables phospholipid scramblase activity. Involved in apoptotic process; embryo development; and engulfment of apoptotic cell. Located in plasma membrane. Is an ortholog of human XKR6 (XK related 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF08F1.5
Corresponding_CDS_historyF08F1.5:wp102
Corresponding_transcriptF08F1.5.1
Other_sequenceAcan_isotig20595
Associated_featureWBsf654212
WBsf1006142
WBsf1006143
WBsf237679
Experimental_infoRNAi_resultWBRNAi00001054Inferred_automaticallyRNAi_primary
WBRNAi00044010Inferred_automaticallyRNAi_primary
WBRNAi00012898Inferred_automaticallyRNAi_primary
WBRNAi00012899Inferred_automaticallyRNAi_primary
WBRNAi00030650Inferred_automaticallyRNAi_primary
Expr_patternExpr11381
Expr1026179
Expr1030238
Expr1147977
Expr2009852
Expr2028092
Drives_constructWBCnstr00016070
WBCnstr00018810
WBCnstr00037554
Construct_productWBCnstr00018810
WBCnstr00037554
Microarray_results (19)
Expression_cluster (183)
InteractionWBInteraction000000972
WBInteraction000001035
WBInteraction000001036
WBInteraction000001037
WBInteraction000001376
WBInteraction000001864
WBInteraction000001867
WBInteraction000004605
WBInteraction000004657
WBInteraction000005452
WBInteraction000009816
WBInteraction000009817
WBInteraction000030041
WBInteraction000030053
WBInteraction000030068
WBInteraction000030069
WBInteraction000052287
WBInteraction000052381
WBInteraction000052383
WBInteraction000153215
WBInteraction000160379
WBInteraction000163072
WBInteraction000165510
WBInteraction000165521
WBInteraction000165533
WBInteraction000165534
WBInteraction000165535
WBInteraction000165573
WBInteraction000172118
WBInteraction000177223
WBInteraction000187410
WBInteraction000198504
WBInteraction000209218
WBInteraction000224053
WBInteraction000238882
WBInteraction000267491
WBInteraction000293913
WBInteraction000301592
WBInteraction000307910
WBInteraction000316955
WBInteraction000330534
WBInteraction000358257
WBInteraction000369292
WBInteraction000369999
WBInteraction000385658
WBInteraction000386503
WBInteraction000391651
WBInteraction000395960
WBInteraction000411724
WBInteraction000411732
WBInteraction000416659
WBInteraction000421318
WBInteraction000427007
WBInteraction000429420
WBInteraction000431014
WBInteraction000431627
WBInteraction000441552
WBInteraction000458816
WBInteraction000460918
WBInteraction000519145
WBInteraction000520805
WBInteraction000521611
WBInteraction000521776
WBInteraction000521780
WBInteraction000541030
WBProcessWBbiopr:00000014
WBbiopr:00000015
Map_infoMapXPosition-0.106284Error0.004973
Well_ordered
PositivePositive_cloneF08F1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point1571
1738
1739
1740
1741
1742
2211
4088
4755
Pos_neg_data4982
4983
4984
Reference (50)
RemarkSequence connection from [Stanfield GM]
MethodGene