WormBase Tree Display for Gene: WBGene00000447
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| WBGene00000447 | SMap | S_parent | Sequence | F55B12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ceh-24 | Person_evidence | WBPerson83 | |||||
| Sequence_name | F55B12.1 | ||||||||
| Molecular_name | F55B12.1 | ||||||||
| F55B12.1.1 | |||||||||
| CE25006 | |||||||||
| Other_name | CELE_F55B12.1 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | ceh-24 | ||||||||
| DB_info | Database | AceView | gene | 5O295 | |||||
| WormQTL | gene | WBGene00000447 | |||||||
| WormFlux | gene | WBGene00000447 | |||||||
| NDB | locus_tag | CELE_F55B12.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000447|UniProtKB=Q9NLC2 | |||||||
| family | PTHR24340 | ||||||||
| NCBI | gene | 179877 | |||||||
| RefSeq | protein | NM_074018.5 | |||||||
| SwissProt | UniProtAcc | Q9NLC2 | |||||||
| UniProt_GCRP | UniProtAcc | Q9NLC2 | |||||||
| OMIM | gene | 600635 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ceh | ||||||||
| Allele (38) | |||||||||
| Legacy_information | [C.elegansII] pk92 : Tc1 insertion, no known phenotype.Encodes NK class homeoprotein. ceh-24:lacZ expressed in pharynx muscle m8, vulval muscles,some head neurons. [PD] | ||||||||
| Strain | WBStrain00030582 | ||||||||
| WBStrain00030580 | |||||||||
| WBStrain00030581 | |||||||||
| WBStrain00008317 | |||||||||
| WBStrain00048954 | |||||||||
| WBStrain00051837 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00000428 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00000434 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000445 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000450 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000449 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000584 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ceh-24 encodes an NK class homeodomain protein orthologous to human NK2 Homeobox 1 (NKX2-1; OMIM:600635) which is expressed in the thyroid, lung, and bronchial epithelia and which, when mutated, leads to disease. | Curator_confirmed | WBPerson1843 | |||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 29 Oct 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; regulation of transcription by RNA polymerase II; and regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Expressed in head muscle; intestine; neurons; non-striated muscle; and ventral nerve cord. Human ortholog(s) of this gene implicated in choreatic disease and thyroid gland papillary carcinoma. Is an ortholog of human NKX2-1 (NK2 homeobox 1) and NKX2-4 (NK2 homeobox 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3969 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11825) | ||||
| DOID:12859 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11825) | ||||||
| Molecular_info | Corresponding_CDS | F55B12.1 | |||||||
| Corresponding_transcript | F55B12.1.1 | ||||||||
| Other_sequence | FD515256.1 | ||||||||
| ACC33915_1 | |||||||||
| EY472969.1 | |||||||||
| Oden_isotig14746 | |||||||||
| MIC05372_1 | |||||||||
| Oden_isotig14745 | |||||||||
| MI06369 | |||||||||
| CSC01139_1 | |||||||||
| JI169963.1 | |||||||||
| Associated_feature | WBsf647488 | ||||||||
| WBsf662047 | |||||||||
| WBsf919538 | |||||||||
| WBsf919539 | |||||||||
| WBsf978299 | |||||||||
| WBsf1001892 | |||||||||
| WBsf1001893 | |||||||||
| WBsf1001894 | |||||||||
| WBsf1020764 | |||||||||
| WBsf232828 | |||||||||
| Transcription_factor | WBTranscriptionFactor000318 | ||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern (18) | |||||||||
| Drives_construct (16) | |||||||||
| Construct_product | WBCnstr00010279 | ||||||||
| WBCnstr00016692 | |||||||||
| WBCnstr00018732 | |||||||||
| WBCnstr00018733 | |||||||||
| WBCnstr00019836 | |||||||||
| WBCnstr00037530 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (93) | |||||||||
| Interaction (35) | |||||||||
| WBProcess | WBbiopr:00000040 | ||||||||
| Map_info | Map | V | Position | 5.59946 | Error | 0.002711 | |||
| Positive | Positive_clone | F55B12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| PD#BH911 | |||||||||
| Mapping_data | Multi_point | 4207 | |||||||
| 5333 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003015 | ||||||||
| WBPaper00003138 | |||||||||
| WBPaper00003174 | |||||||||
| WBPaper00004154 | |||||||||
| WBPaper00004568 | |||||||||
| WBPaper00005080 | |||||||||
| WBPaper00005324 | |||||||||
| WBPaper00010387 | |||||||||
| WBPaper00011002 | |||||||||
| WBPaper00011243 | |||||||||
| WBPaper00011778 | |||||||||
| WBPaper00012554 | |||||||||
| WBPaper00015048 | |||||||||
| WBPaper00015155 | |||||||||
| WBPaper00015409 | |||||||||
| WBPaper00021812 | |||||||||
| WBPaper00022346 | |||||||||
| WBPaper00026440 | |||||||||
| WBPaper00027104 | |||||||||
| WBPaper00027309 | |||||||||
| WBPaper00029033 | |||||||||
| WBPaper00031196 | |||||||||
| WBPaper00031696 | |||||||||
| WBPaper00034603 | |||||||||
| WBPaper00034727 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041190 | |||||||||
| WBPaper00048493 | |||||||||
| WBPaper00050847 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060123 | |||||||||
| WBPaper00061738 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
