WormBase Tree Display for Gene: WBGene00000447
expand all nodes | collapse all nodes | view schema
WBGene00000447 | SMap | S_parent | Sequence | F55B12 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ceh | ||||||
Allele (38) | |||||||
Legacy_information | [C.elegansII] pk92 : Tc1 insertion, no known phenotype.Encodes NK class homeoprotein. ceh-24:lacZ expressed in pharynx muscle m8, vulval muscles,some head neurons. [PD] | ||||||
Strain | WBStrain00030582 | ||||||
WBStrain00030580 | |||||||
WBStrain00030581 | |||||||
WBStrain00008317 | |||||||
WBStrain00048954 | |||||||
WBStrain00051837 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (14) | |||||||
Ortholog (36) | |||||||
Paralog | WBGene00000428 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00000434 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000445 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00000450 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000449 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000584 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | ceh-24 encodes an NK class homeodomain protein orthologous to human NK2 Homeobox 1 (NKX2-1; OMIM:600635) which is expressed in the thyroid, lung, and bronchial epithelia and which, when mutated, leads to disease. | Curator_confirmed | WBPerson1843 | |||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 29 Oct 2009 00:00:00 | ||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; regulation of transcription by RNA polymerase II; and regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Expressed in head muscle; intestine; neurons; non-striated muscle; and ventral nerve cord. Human ortholog(s) of this gene implicated in choreatic disease and thyroid gland papillary carcinoma. Is an ortholog of human NKX2-1 (NK2 homeobox 1) and NKX2-4 (NK2 homeobox 4). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:3969 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11825) | ||
DOID:12859 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11825) | ||||
Molecular_info | Corresponding_CDS | F55B12.1 | |||||
Corresponding_transcript | F55B12.1.1 | ||||||
Other_sequence | FD515256.1 | ||||||
ACC33915_1 | |||||||
EY472969.1 | |||||||
Oden_isotig14746 | |||||||
MIC05372_1 | |||||||
Oden_isotig14745 | |||||||
MI06369 | |||||||
CSC01139_1 | |||||||
JI169963.1 | |||||||
Associated_feature | WBsf647488 | ||||||
WBsf662047 | |||||||
WBsf919538 | |||||||
WBsf919539 | |||||||
WBsf978299 | |||||||
WBsf1001892 | |||||||
WBsf1001893 | |||||||
WBsf1001894 | |||||||
WBsf1020764 | |||||||
WBsf232828 | |||||||
Transcription_factor | WBTranscriptionFactor000318 | ||||||
Experimental_info | RNAi_result (16) | ||||||
Expr_pattern (18) | |||||||
Drives_construct (16) | |||||||
Construct_product | WBCnstr00010279 | ||||||
WBCnstr00016692 | |||||||
WBCnstr00018732 | |||||||
WBCnstr00018733 | |||||||
WBCnstr00019836 | |||||||
WBCnstr00037530 | |||||||
Microarray_results (20) | |||||||
Expression_cluster (93) | |||||||
Interaction (35) | |||||||
WBProcess | WBbiopr:00000040 | ||||||
Map_info | Map | V | Position | 5.59946 | Error | 0.002711 | |
Positive | Positive_clone | F55B12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
PD#BH911 | |||||||
Mapping_data | Multi_point | 4207 | |||||
5333 | |||||||
Pseudo_map_position | |||||||
Reference (32) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |