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WormBase Tree Display for Gene: WBGene00000585

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Name Class

WBGene00000585SMapS_parentSequenceC06G3
IdentityVersion2
NameCGC_namecogc-2Paper_evidenceWBPaper00026979
Person_evidenceWBPerson449
Sequence_nameC06G3.10
Molecular_nameC06G3.10
C06G3.10.1
CE28817
Other_namecog2Accession_evidenceEMBLZ34976
cgo-2
CELE_C06G3.10Accession_evidenceNDBBX284604
Public_namecogc-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
217 Jan 2006 13:29:50WBPerson2970Name_changeCGC_namecogc-2
Other_namecgo-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcogc
Allele (33)
RNASeq_FPKM (74)
GO_annotation (12)
Contained_in_operonCEOP4208
Ortholog (28)
Structured_descriptionConcise_descriptioncogc-2 encodes an ortholog of mammalian COG-2, a subunit of lobe A ofthe conserved oligomeric Golgi complex (COGC); COGC-2 is required fornormal gonadal distal tip cell migration, a process that also requiresseven other orthologs of COGC subunits; like other lobe A subunits inboth C. elegans and S. cerevisiae, COGC-2 is strongly required fornormal function, while lobe B subunits are only partially required ineither worms or yeast.Paper_evidenceWBPaper00026979
WBPaper00028363
WBPaper00028599
WBPaper00028603
Curator_confirmedWBPerson567
Date_last_updated25 Oct 2006 00:00:00
Automated_descriptionInvolved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIq. Is an ortholog of human COG2 (component of oligomeric golgi complex 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070269Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6546)
Molecular_infoCorresponding_CDSC06G3.10
Corresponding_transcriptC06G3.10.1
Other_sequence (23)
Associated_featureWBsf651882
WBsf981776
WBsf230214
WBsf230215
Experimental_infoRNAi_resultWBRNAi00105639Inferred_automaticallyRNAi_primary
WBRNAi00105630Inferred_automaticallyRNAi_primary
WBRNAi00105641Inferred_automaticallyRNAi_primary
WBRNAi00105622Inferred_automaticallyRNAi_primary
WBRNAi00105640Inferred_automaticallyRNAi_primary
WBRNAi00105644Inferred_automaticallyRNAi_primary
WBRNAi00105634Inferred_automaticallyRNAi_primary
WBRNAi00105623Inferred_automaticallyRNAi_primary
WBRNAi00105619Inferred_automaticallyRNAi_primary
WBRNAi00039929Inferred_automaticallyRNAi_primary
WBRNAi00105632Inferred_automaticallyRNAi_primary
WBRNAi00105624Inferred_automaticallyRNAi_primary
WBRNAi00113427Inferred_automaticallyRNAi_primary
WBRNAi00105621Inferred_automaticallyRNAi_primary
WBRNAi00105625Inferred_automaticallyRNAi_primary
WBRNAi00105635Inferred_automaticallyRNAi_primary
WBRNAi00000402Inferred_automaticallyRNAi_primary
WBRNAi00105627Inferred_automaticallyRNAi_primary
WBRNAi00085850Inferred_automaticallyRNAi_primary
WBRNAi00008355Inferred_automaticallyRNAi_primary
WBRNAi00105626Inferred_automaticallyRNAi_primary
WBRNAi00030283Inferred_automaticallyRNAi_primary
WBRNAi00105637Inferred_automaticallyRNAi_primary
WBRNAi00105631Inferred_automaticallyRNAi_primary
WBRNAi00105642Inferred_automaticallyRNAi_primary
WBRNAi00105620Inferred_automaticallyRNAi_primary
WBRNAi00024492Inferred_automaticallyRNAi_primary
WBRNAi00105645Inferred_automaticallyRNAi_primary
WBRNAi00105638Inferred_automaticallyRNAi_primary
WBRNAi00064300Inferred_automaticallyRNAi_primary
WBRNAi00105628Inferred_automaticallyRNAi_primary
WBRNAi00065693Inferred_automaticallyRNAi_primary
WBRNAi00105643Inferred_automaticallyRNAi_primary
WBRNAi00105633Inferred_automaticallyRNAi_primary
WBRNAi00105636Inferred_automaticallyRNAi_primary
WBRNAi00105629Inferred_automaticallyRNAi_primary
Expr_patternExpr1021050
Expr1030345
Expr1144006
Expr2010291
Expr2028533
Drives_constructWBCnstr00037444
Construct_productWBCnstr00037444
Microarray_results (19)
Expression_cluster (117)
Interaction (19)
Map_infoMapIVPosition3.27829Error0.000592
PositivePositive_cloneC06G3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027766
WBPaper00038491
WBPaper00055090
WBPaper00061547
RemarkC06G3.10 was incorrectly linked to cog-2. C06G3.10 is required for normal Golgi morphology and function and has nothing to do with cog - Connection Of Gonad defective. The EMBL gene name cog2 refers to a Golgi-localized protein complex. However, "cog" is not CGC approvedCGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene