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WormBase Tree Display for Gene: WBGene00000797

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Name Class

WBGene00000797EvidencePaper_evidenceWBPaper00005857
SMapS_parentSequenceAH9
IdentityVersion1
NameCGC_namecrn-4Person_evidenceWBPerson1606
Sequence_nameAH9.2
Molecular_nameAH9.2
AH9.2.1
CE03858
Other_nameCELE_AH9.2Accession_evidenceNDBBX284606
Public_namecrn-4
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcrn
Allele (44)
In_clusterconserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (38)
ParalogWBGene00001332Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00019724Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00019825Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptioncrn-4 encodes a DEDD family DNase, a cell death-related nuclease; crn-4 exhibits both DNase and RNase activities; crn-4 is believed to function in a large multinuclease complex, the degradeosome, whose components include the protein products of cps-6, crn-1, crn-5, cpy-13 and other non-nuclease components like wah-1, to promote apoptotic DNA degradation; crn-4 has been shown to bind DNA through its Zn-domain and cleave it through its N-terminal DEDDh domain; crn-4 interacts with crn-5 in protein binding experiments, this interaction has been shown to enhance crn-4 DNAase activity.Paper_evidenceWBPaper00005857
WBPaper00032328
WBPaper00036712
Curator_confirmedWBPerson324
Date_last_updated22 Oct 2010 00:00:00
Automated_descriptionEnables nuclease activity and single-stranded DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Predicted to be located in cytoplasm. Is an ortholog of human ERI1 (exoribonuclease 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSAH9.2
Corresponding_transcriptAH9.2.1
Other_sequenceCRC10371_1
Associated_featureWBsf1004276
WBsf1004277
WBsf1004278
WBsf1022435
WBsf237066
Experimental_infoRNAi_resultWBRNAi00097988Inferred_automaticallyRNAi_primary
WBRNAi00009537Inferred_automaticallyRNAi_primary
WBRNAi00027934Inferred_automaticallyRNAi_primary
WBRNAi00038628Inferred_automaticallyRNAi_primary
WBRNAi00087548Inferred_automaticallyRNAi_primary
Expr_patternExpr1011892
Expr1030496
Expr1142836
Expr2010539
Expr2028779
Drives_constructWBCnstr00037269
Construct_productWBCnstr00037269
Microarray_results (15)
Expression_cluster (152)
Interaction (16)
WBProcessWBbiopr:00000014
WBbiopr:00000103
Map_infoMapXPosition-15.9429Error0.04732
PositivePositive_cloneAH9Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005857
WBPaper00006283
WBPaper00019408
WBPaper00027291
WBPaper00032328
WBPaper00036712
WBPaper00053142
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene