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WormBase Tree Display for Gene: WBGene00000895

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Name Class

WBGene00000895SMapS_parentSequenceB0412
IdentityVersion1
NameCGC_namedac-1Person_evidenceWBPerson473
Sequence_nameB0412.1
Molecular_nameB0412.1a
B0412.1a.1
CE26848
B0412.1b
CE33550
B0412.1b.1
Other_nameski-1Person_evidenceWBPerson473
CELE_B0412.1Accession_evidenceNDBBX284603
Public_namedac-1
DB_infoDatabaseAceViewgene3B439
WormQTLgeneWBGene00000895
WormFluxgeneWBGene00000895
NDBlocus_tagCELE_B0412.1
PanthergeneCAEEL|WormBase=WBGene00000895|UniProtKB=H2KY91
familyPTHR12577
NCBIgene175238
RefSeqproteinNM_001025959.5
NM_001025958.4
SwissProtUniProtAccH2KY91
TREEFAMTREEFAM_IDTF316697
UniProt_GCRPUniProtAccH2KY91
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdac
AlleleWBVar00249697
WBVar00031888
WBVar01272284
WBVar00095465
WBVar00095466
WBVar00031913
WBVar01500082
WBVar00031923
WBVar00031928
WBVar00006766
WBVar00031953
WBVar00006771
WBVar00006776
WBVar01499552
WBVar00006781
WBVar00006786
WBVar00031978
WBVar02069533
WBVar00006791
WBVar02069534
WBVar00031983
WBVar00006796
WBVar01903499
WBVar01769203
WBVar00031988
WBVar01769204
WBVar00006801
WBVar01769205
WBVar01498832
WBVar01769206
WBVar01769207
WBVar00006806
WBVar00031998
WBVar00006811
WBVar00032008
WBVar00006816
WBVar00032013
WBVar00006821
WBVar00032018
WBVar00006826
WBVar00032023
WBVar00006831
WBVar00006836
WBVar00006841
WBVar00006846
WBVar00006851
WBVar02030158
WBVar02030159
WBVar00006856
WBVar01951231
WBVar02030160
WBVar01951232
WBVar00006861
WBVar01400723
WBVar00006866
WBVar00799577
WBVar00006871
WBVar00799578
WBVar00799579
WBVar00006876
WBVar00799580
WBVar00799581
WBVar00300917
WBVar00799582
WBVar00799583
WBVar00799584
WBVar00235329
WBVar00799585
WBVar00799586
WBVar00799587
WBVar00799588
WBVar00799589
WBVar02085187
WBVar00799590
WBVar00799591
WBVar00799592
WBVar00799593
WBVar00799594
WBVar00799595
WBVar00799596
WBVar00799597
WBVar00799598
WBVar01322504
WBVar00799599
WBVar01322505
WBVar01322507
WBVar00799600
WBVar00799601
WBVar00799602
WBVar00799603
WBVar01564410
WBVar00799604
WBVar01564411
WBVar00799605
WBVar01564412
WBVar01564413
WBVar00799606
WBVar00799607
WBVar01564414
WBVar01255184
WBVar00799608
WBVar01564415
WBVar00799609
WBVar01255187
WBVar01255189
WBVar00799610
WBVar01255190
WBVar00799611
WBVar00799612
WBVar01255191
WBVar00799613
WBVar01255206
WBVar01255208
WBVar01255209
WBVar01255216
WBVar00388687
WBVar00388688
WBVar00388689
WBVar00388690
WBVar00388691
WBVar00388692
WBVar01937793
WBVar00388693
WBVar00388694
WBVar02117616
WBVar00388695
WBVar00388696
WBVar00388697
WBVar00388698
WBVar01917775
WBVar01917777
WBVar00388699
WBVar01944401
WBVar00388700
WBVar01917778
WBVar01944402
WBVar00388701
WBVar01917779
WBVar00388702
WBVar01479063
WBVar01401093
WBVar01401094
WBVar01401095
WBVar00145605
WBVar02081376
WBVar02081377
WBVar02081378
WBVar02079902
WBVar01506144
WBVar02080095
WBVar01506145
WBVar01506146
WBVar00145618
WBVar01506147
WBVar00145620
WBVar00559368
WBVar00559370
WBVar01272262
WBVar01272273
StrainWBStrain00001324
WBStrain00001325
WBStrain00035649
WBStrain00035733
WBStrain00035736
RNASeq_FPKM (74)
GO_annotation00021457
00021458
00021459
00021460
00021461
00021462
00021463
00021464
00021465
Ortholog (36)
Structured_descriptionConcise_descriptiondac-1 encodes the C. elegans ortholog of Dachshund, a transcriptional regulator first described in Drosophila that is a member of the SKI/SNO/DAC family of proteins; dac-1 is expressed at higher levels in the AFD thermosensory neurons as compared to the AWB olfactory neurons and likely plays a role in thermosensory behavior as on thermal gradients dac-1 mutants fail to suppress cryophilic drive but continue to track isotherms at the cultivation temperature; a DAC-1::GFP fusion protein is nuclear and expressed strongly in the AFD thermosensory neurons, but weakly in the AWC, ASE, and ASK chemosensory neurons; expression is also seen in alae and additional, unidentified tail cells; dac-1 expression in AFD is positively regulated by the TTX-1 OTX-like homeodomain protein.Paper_evidenceWBPaper00024671
Curator_confirmedWBPerson1843
Date_last_updated21 May 2007 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in thermotaxis. Located in nucleus. Expressed in amphid neurons; cuticular ala; and tail. Is an ortholog of human DACH1 (dachshund family transcription factor 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSB0412.1a
B0412.1b
Corresponding_CDS_historyB0412.1b:wp120
B0412.1b:wp123
Corresponding_transcriptB0412.1a.1
B0412.1b.1
Other_sequenceDviv_isotig11489
SSC00720_1
Dviv_isotig11488
SS02097
Associated_featureWBsf658584
WBsf978943
WBsf224400
Transcription_factorWBTranscriptionFactor000635
Experimental_infoRNAi_resultWBRNAi00028128Inferred_automaticallyRNAi_primary
WBRNAi00009756Inferred_automaticallyRNAi_primary
WBRNAi00006647Inferred_automaticallyRNAi_primary
WBRNAi00110961Inferred_automaticallyRNAi_primary
WBRNAi00039031Inferred_automaticallyRNAi_primary
Expr_patternChronogram2070
Expr3130
Expr5066
Expr7403
Expr1015167
Expr1143193
Expr1200045
Expr2010758
Expr2028995
Drives_constructWBCnstr00002217
WBCnstr00002218
WBCnstr00011158
WBCnstr00012546
WBCnstr00037214
Construct_productWBCnstr00011158
WBCnstr00016702
WBCnstr00037214
Microarray_results (24)
Expression_cluster (120)
Interaction (95)
WBProcessWBbiopr:00000010
Map_infoMapIIIPosition-25.7793Error0.003862
PositivePositive_cloneB0412Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4251
Pseudo_map_position
ReferenceWBPaper00010874
WBPaper00024524
WBPaper00024671
WBPaper00026952
WBPaper00027309
WBPaper00033137
WBPaper00034843
WBPaper00038491
WBPaper00055090
WBPaper00065158
Remarkski-1 became an other-name of dac-1 as this locus encodes the C. elegans ortholog of Dachshund, rather than of the related protein SKIPerson_evidenceWBPerson473
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene