WormBase Tree Display for Gene: WBGene00000906
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| WBGene00000906 | SMap | S_parent | Sequence | F23B2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | daf-10 | Person_evidence | WBPerson521 | |||||
| WBPerson41163 | |||||||||
| Sequence_name | F23B2.4 | ||||||||
| Molecular_name | F23B2.4 | ||||||||
| F23B2.4.1 | |||||||||
| CE40504 | |||||||||
| Other_name | osm-4 | ||||||||
| ift-122 | Person_evidence | WBPerson41163 | |||||||
| CELE_F23B2.4 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | daf-10 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 16 Jun 2006 16:39:11 | WBPerson2970 | Event | Acquires_merge | WBGene00009074 | ||||
| 3 | 05 May 2023 12:43:53 | WBPerson51134 | Name_change | CGC_name | daf-10 | ||||
| Other_name | ift-122 | ||||||||
| Acquires_merge | WBGene00009074 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | daf | ||||||||
| Reference_allele | WBVar00143964 | ||||||||
| Allele (124) | |||||||||
| Legacy_information | e1387 : defective dauer formation (daf-8 daf-2 suppressible) abnormal chemotaxis abnormal osmotic avoidance males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells cephalic neurons; octopamine deficient. ES1. ME0. NA2 (m79 p821 pka osm-4). | ||||||||
| See daf-10. | |||||||||
| See also e1387, p821 | |||||||||
| [C.elegansII] e1387 : defective dauer formation; abnormal chemotaxis abnormal osmotic avoidance; males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells, cephalic neurons; Dyf (FITC uptake defective); octopamine deficient. ES1. ME0. OA10: m79, p821 (pka osm-4), m534mut, mn321mut, etc. [Starich et al. 1995; DR; SP] | |||||||||
| Strain | WBStrain00030799 | ||||||||
| WBStrain00036760 | |||||||||
| WBStrain00004318 | |||||||||
| WBStrain00004878 | |||||||||
| WBStrain00006213 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (43) | |||||||||
| Structured_description | Concise_description | daf-10 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex A component IFT122; daf-10 activity is required for intraflagellar transport and thus for proper development of amphid and phasmid neurons, dauer development, chemotaxis, and normal lifespan; a DAF-10::GFP fusion protein undergoes both anterograde and retrograde intraflagellar transport in amphid or phasmid sensory neurons. | Paper_evidence | WBPaper00000503 | |||||
| WBPaper00001393 | |||||||||
| WBPaper00001482 | |||||||||
| WBPaper00002087 | |||||||||
| WBPaper00003835 | |||||||||
| WBPaper00004715 | |||||||||
| WBPaper00026822 | |||||||||
| WBPaper00027360 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 23 Feb 2007 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including non-motile cilium assembly; positive regulation of dauer larval development; and receptor localization to non-motile cilium. Located in ciliary basal body. Human ortholog(s) of this gene implicated in cranioectodermal dysplasia 1. Is an ortholog of human IFT122 (intraflagellar transport 122). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080803 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13556) | ||||
| Molecular_info | Corresponding_CDS | F23B2.4 | |||||||
| Corresponding_CDS_history | F23B2.4:wp164 | ||||||||
| F23B2.4:wp166 | |||||||||
| Corresponding_transcript | F23B2.4.1 | ||||||||
| Other_sequence (13) | |||||||||
| Associated_feature | WBsf652038 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00098609 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00013805 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098640 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045391 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098675 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098722 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1015512 | ||||||||
| Expr1030569 | |||||||||
| Expr1149314 | |||||||||
| Expr2010760 | |||||||||
| Expr2028997 | |||||||||
| Drives_construct | WBCnstr00037204 | ||||||||
| Construct_product | WBCnstr00008557 | ||||||||
| WBCnstr00017221 | |||||||||
| WBCnstr00017229 | |||||||||
| WBCnstr00037204 | |||||||||
| Regulate_expr_cluster | WBPaper00041876:daf-10(m79)_downreglated | ||||||||
| WBPaper00041876:daf-10(m79)_upreglated | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (140) | |||||||||
| Interaction | WBInteraction000000237 | ||||||||
| WBInteraction000001204 | |||||||||
| WBInteraction000004673 | |||||||||
| WBInteraction000004699 | |||||||||
| WBInteraction000137910 | |||||||||
| WBInteraction000416368 | |||||||||
| WBInteraction000444319 | |||||||||
| WBInteraction000502223 | |||||||||
| WBInteraction000519390 | |||||||||
| WBInteraction000519391 | |||||||||
| WBInteraction000519392 | |||||||||
| WBInteraction000519393 | |||||||||
| WBInteraction000519394 | |||||||||
| WBInteraction000519395 | |||||||||
| WBInteraction000519396 | |||||||||
| WBInteraction000519397 | |||||||||
| WBInteraction000519398 | |||||||||
| WBInteraction000519399 | |||||||||
| WBInteraction000519400 | |||||||||
| WBInteraction000519401 | |||||||||
| WBInteraction000519402 | |||||||||
| WBInteraction000519403 | |||||||||
| WBInteraction000519404 | |||||||||
| WBInteraction000519405 | |||||||||
| WBInteraction000519406 | |||||||||
| WBInteraction000519407 | |||||||||
| WBInteraction000519408 | |||||||||
| WBInteraction000519409 | |||||||||
| WBInteraction000519410 | |||||||||
| WBInteraction000519411 | |||||||||
| WBInteraction000542918 | |||||||||
| WBInteraction000571245 | |||||||||
| Map_info | Map | IV | Position | 4.05374 | Error | 0.000504 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | EH#5 | |||||||
| F23B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | 2_point | 366 | |||||||
| 367 | |||||||||
| 429 | |||||||||
| 430 | |||||||||
| Multi_point | 1125 | ||||||||
| 3239 | |||||||||
| Reference (86) | |||||||||
| Method | Gene |
