WormBase Tree Display for Gene: WBGene00000994
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| WBGene00000994 | Evidence | Author_evidence | Koo H-S | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CHROMOSOME_IV | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | ints-6 | Person_evidence | WBPerson5934 | |||||
| Sequence_name | F08B4.1 | ||||||||
| Molecular_name | F08B4.1a | ||||||||
| F08B4.1a.1 | |||||||||
| CE43390 | |||||||||
| F08B4.1b | |||||||||
| CE43330 | |||||||||
| F08B4.1b.1 | |||||||||
| Other_name | dic-1 | ||||||||
| CELE_F08B4.1 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | ints-6 | ||||||||
| DB_info | Database | AceView | gene | 4J459 | |||||
| WormQTL | gene | WBGene00000994 | |||||||
| NDB | locus_tag | CELE_F08B4.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000994|UniProtKB=B7WN63 | |||||||
| family | PTHR12957 | ||||||||
| NCBI | gene | 24104403 | |||||||
| RefSeq | protein | NM_001307283.3 | |||||||
| NM_001307284.2 | |||||||||
| TREEFAM | TREEFAM_ID | TF323386 | |||||||
| TrEMBL | UniProtAcc | H2KZC8 | |||||||
| B7WN63 | |||||||||
| UniProt_GCRP | UniProtAcc | B7WN63 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 May 2019 14:10:26 | WBPerson1983 | Name_change | CGC_name | ints-6 | ||||
| Other_name | dic-1 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ints | ||||||||
| Allele (74) | |||||||||
| Strain | WBStrain00028636 | ||||||||
| WBStrain00022206 | |||||||||
| WBStrain00022215 | |||||||||
| WBStrain00022211 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00006461 | ||||||||
| 00006462 | |||||||||
| Ortholog (44) | |||||||||
| Structured_description | Concise_description | dic-1 encodes an ortholog of Drosophila CG3125 and human DEAD/H BOX 26 (DDX26, DICE-1; OMIM:604331; nuclear protein, lost or downregulated in non-small cell lung carcinomas); DIC-1 and its orthologs have an N-terminal von Willebrand factor (vWF) type A domain; DIC-1 is essential for normal mitochondrial morphology and function, particularly that of the mitochondrial cristae/inner membrane; dic-1 thus plays a role in oogenesis, apoptosis, embryonic and larval development, and locomotion; in C. elegans, DIC-1 is expressed ubiquitously and localizes to the cristae of the inner mitochondrial membrane. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00006395 | |||||||||
| WBPaper00012781 | |||||||||
| WBPaper00012894 | |||||||||
| WBPaper00013040 | |||||||||
| WBPaper00013206 | |||||||||
| WBPaper00028418 | |||||||||
| WBPaper00032903 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 26 Aug 2009 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. Expressed in several structures, including neurons. Is an ortholog of human INTS6 (integrator complex subunit 6) and INTS6L (integrator complex subunit 6 like). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F08B4.1a | |||||||
| F08B4.1b | |||||||||
| Corresponding_CDS_history | F08B4.1:wp129 | ||||||||
| F08B4.1a:wp197 | |||||||||
| F08B4.1b:wp197 | |||||||||
| Corresponding_transcript | F08B4.1a.1 | ||||||||
| F08B4.1b.1 | |||||||||
| Other_sequence | MC01216 | ||||||||
| CR04295 | |||||||||
| CJC02448_1 | |||||||||
| CR04448 | |||||||||
| CBC10596_1 | |||||||||
| CRC11080_1 | |||||||||
| Associated_feature | WBsf660432 | ||||||||
| WBsf228727 | |||||||||
| Experimental_info | RNAi_result (25) | ||||||||
| Expr_pattern | Expr4275 | ||||||||
| Expr4276 | |||||||||
| Expr4587 | |||||||||
| Expr14307 | |||||||||
| Expr1015367 | |||||||||
| Expr1030619 | |||||||||
| Expr1147940 | |||||||||
| Expr2010924 | |||||||||
| Expr2029163 | |||||||||
| Drives_construct | WBCnstr00012096 | ||||||||
| WBCnstr00037151 | |||||||||
| WBCnstr00040565 | |||||||||
| Construct_product | WBCnstr00005572 | ||||||||
| WBCnstr00011879 | |||||||||
| WBCnstr00037151 | |||||||||
| WBCnstr00040565 | |||||||||
| Regulate_expr_cluster | WBPaper00056284:ints-6(t1903)_downregulated | ||||||||
| WBPaper00056284:ints-6(t1903)_upregulated | |||||||||
| WBPaper00056284:INTS-6_interacting_protein | |||||||||
| Antibody | WBAntibody00001139 | ||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (108) | |||||||||
| Interaction (24) | |||||||||
| Map_info | Map | IV | Position | 3.94356 | Error | 0.003705 | |||
| Positive | Positive_clone | F08B4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4940 | |||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
