WormBase Tree Display for Gene: WBGene00001123
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| WBGene00001123 | SMap | S_parent | Sequence | C43C3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | dyf-7 | Person_evidence | WBPerson252 | |||||
| Sequence_name | C43C3.3 | ||||||||
| Molecular_name | C43C3.3 | ||||||||
| C43C3.3.1 | |||||||||
| CE23591 | |||||||||
| Other_name | dyf-8 | Paper_evidence | WBPaper00033050 | ||||||
| CELE_C43C3.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | dyf-7 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00001123 | |||||
| WormFlux | gene | WBGene00001123 | |||||||
| NDB | locus_tag | CELE_C43C3.3 | |||||||
| Panther | gene | CAEEL|Gene=C43C3.3|UniProtKB=Q09276 | |||||||
| family | PTHR47327 | ||||||||
| NCBI | gene | 181183 | |||||||
| RefSeq | protein | NM_001392826.1 | |||||||
| SwissProt | UniProtAcc | Q09276 | |||||||
| TREEFAM | TREEFAM_ID | TF353410 | |||||||
| UniProt_GCRP | UniProtAcc | Q09276 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 26 Apr 2010 16:20:02 | WBPerson2970 | Event | Acquires_merge | WBGene00001124 | ||||
| Name_change | Sequence_name | C43C3.3 | |||||||
| 3 | 08 Aug 2016 09:46:50 | WBPerson2970 | Name_change | Other_name | dyf-8 | ||||
| Acquires_merge | WBGene00001124 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dyf | ||||||||
| Allele (58) | |||||||||
| Legacy_information | [Herman RK] Defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME1 | ||||||||
| [C.elegansII] m537mut : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME1 [Starich et al. 1995] | |||||||||
| [C.elegansII] m539mut : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Animals slightly short. Chemotaxis defective. ME1. [Starich et al. 1995] | |||||||||
| Complementation_data | [Herman RK] dyf-7(m537) complements dyf-12(sa127), dyf-6(mn346), daf-12(m20), and vab-3(e648) with respect to dye filling. | ||||||||
| Strain | WBStrain00002483 | ||||||||
| WBStrain00002667 | |||||||||
| WBStrain00034355 | |||||||||
| WBStrain00034386 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (28) | |||||||||
| Structured_description | Concise_description | dyf-7 encodes a protein containing a single-pass transmembrane domain, a small cytoplasmic domain, and a large extra-cellular/luminal domain related to that of zona pellucida (ZP) proteins, components of the matrix surrounding vertebrate oocytes to which sperm bind; dyf-7 is required for anchoring dendritic tips during cell body migration: in dyf-7 embryos, neurons are born at the proper position and form projections toward the nose, but dendritic tips fail to remain anchored during cell body migration, were dragged along the migrating cell body and eventually disappeared; the ability of DYF-7 to anchor dendritic tips is associated with multimerization and, by extension, matrix formation; a dyf-7 promotor fusion is expressed in most sensory neuron, including all amphid sensory neurons; subcellularly, DYF-7-GFP accumulates in bright puncta at dendritic tips during retrograde extension, especially in the novel domain adjacent to the sensory cilium, and weakly in the plasma membrane of the dendrite and cell body; when expressed in S2 cells, DYF-7 is proteolytically processed, with some of the resulting molecules secreted and some retained in the cytoplasm. | Paper_evidence | WBPaper00033050 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| WBPerson12884 | |||||||||
| Date_last_updated | 02 Jun 2011 00:00:00 | ||||||||
| Automated_description | Enables protein self-association. Involved in amphid sensory organ dendrite retrograde extension and neuron projection extension. Located in dendrite membrane. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C43C3.3 | |||||||
| Corresponding_transcript | C43C3.3.1 | ||||||||
| Other_sequence | OVC02847_1 | ||||||||
| JI172741.1 | |||||||||
| JI466757.1 | |||||||||
| JI460948.1 | |||||||||
| PPC03043_1 | |||||||||
| AI540037.1 | |||||||||
| Associated_feature | WBsf648426 | ||||||||
| WBsf663186 | |||||||||
| WBsf1006508 | |||||||||
| WBsf1006509 | |||||||||
| WBsf1006510 | |||||||||
| WBsf1023613 | |||||||||
| WBsf1023614 | |||||||||
| WBsf236190 | |||||||||
| WBsf236191 | |||||||||
| WBsf236192 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00011880 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00042371 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00003073 | ||||||||
| WBCnstr00004527 | |||||||||
| WBCnstr00004532 | |||||||||
| WBCnstr00005604 | |||||||||
| WBCnstr00009481 | |||||||||
| WBCnstr00015224 | |||||||||
| WBCnstr00015353 | |||||||||
| WBCnstr00037995 | |||||||||
| WBCnstr00041422 | |||||||||
| WBCnstr00042780 | |||||||||
| Construct_product | WBCnstr00037995 | ||||||||
| WBCnstr00041422 | |||||||||
| WBCnstr00042780 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (179) | |||||||||
| Interaction | WBInteraction000540827 | ||||||||
| WBInteraction000569693 | |||||||||
| Map_info | Map | X | Position | 1.45704 | Error | 0.00305 | |||
| Positive | Positive_clone | C43C3 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 3088 | |||||||
| 3089 | |||||||||
| 3093 | |||||||||
| 3092 | |||||||||
| 5573 | |||||||||
| Pos_neg_data | 8326 | ||||||||
| 8328 | |||||||||
| Reference (39) | |||||||||
| Method | Gene |
