| WBGene00001193 | SMap | S_parent | Sequence | C23H3 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | egl-26 | Person_evidence | WBPerson268 |
| | | Sequence_name | C23H3.1 |
| | | Molecular_name | C23H3.1a |
| | | | C23H3.1a.1 |
| | | | CE08320 |
| | | | C23H3.1b |
| | | | CE50533 |
| | | | C23H3.1b.1 |
| | | Other_name | egl-48 |
| | | | cog-4 |
| | | | CELE_C23H3.1 | Accession_evidence | NDB | BX284602 |
| | | Public_name | egl-26 |
| | DB_info | Database | AceView | gene | 2A377 |
| | | | WormQTL | gene | WBGene00001193 |
| | | | WormFlux | gene | WBGene00001193 |
| | | | NDB | locus_tag | CELE_C23H3.1 |
| | | | Panther | gene | CAEEL|EnsemblGenome=WBGene00001193|UniProtKB=P91082 |
| | | | | family | PTHR36948 |
| | | | NCBI | gene | 173392 |
| | | | RefSeq | protein | NM_001313583.2 |
| | | | | | NM_061251.6 |
| | | | SwissProt | UniProtAcc | P91082 |
| | | | UniProt_GCRP | UniProtAcc | P91082 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | egl |
| | Reference_allele | WBVar00089528 |
| | Allele (31) |
| | Legacy_information | n481 : variable bloating Type A many animals form bag-of-worms (60%); abnormal vulva. ES2 adult. NA1. |
| | | See also e1952, n481 |
| | | [C.elegansII] n481 : variable bloating, insensitive to serotonin and imipramine; 60% adults form bag-of-worms; abnormal vulva; suppressor of Tra-3. ES2 adult. ME3. OA1: e1952 (pka egl-48, HME1/2, stronger suppressor of Tra-3). [Trent et al. 1983; Hodgkin 1986; CB; MT] |
| | Strain | WBStrain00026509 |
| | | WBStrain00026781 |
| | | WBStrain00026856 |
| | | WBStrain00004534 |
| | | WBStrain00004636 |
| | RNASeq_FPKM (74) |
| | GO_annotation (15) |
| | Ortholog (27) |
| | Structured_description | Concise_description | egl-26 encodes a protein that contains an H-box and an NC domain that is a member of the LRAT (lecithin retinol acyltransferase) subfamily of the NlpC/P60 superfamily of enzymes; egl-26 activity is required for fertility, egg laying, and vulval development, specifically the connection of the uterus to the vulva mediated by proper morphogenesis of vulF, the most dorsal vulval cell; EGL-26 is an apical membrane protein that is expressed in many cells, including vulF, and appears to be expressed near the vulva and uterus only during the L4 larval stage; EGL-26 membrane localization is necessary for its function. | Paper_evidence | WBPaper00000635 |
| | | | | | WBPaper00005103 |
| | | | | | WBPaper00030762 |
| | | | | Curator_confirmed | WBPerson48 |
| | | | | | WBPerson1843 |
| | | | | Date_last_updated | 07 Aug 2007 00:00:00 |
| | | Automated_description | Predicted to enable acyltransferase activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and vulval development. Located in cytoplasmic side of apical plasma membrane. Expressed in several structures, including buccal cavity; excretory canal; hermaphrodite gonad; rectum; and vulval cell. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | C23H3.1a |
| | | C23H3.1b |
| | Corresponding_transcript | C23H3.1a.1 |
| | | C23H3.1b.1 |
| | Other_sequence | CR12698 |
| | | CJC02584_1 |
| | | CGC00868_1 |
| | | CRC04517_1 |
| | Associated_feature | WBsf654854 |
| | | WBsf717611 |
| | | WBsf717612 |
| | | WBsf986311 |
| | | WBsf986312 |
| Experimental_info | RNAi_result (12) |
| | Expr_pattern (11) |
| | Drives_construct | WBCnstr00000797 |
| | | WBCnstr00006433 |
| | | WBCnstr00010463 |
| | | WBCnstr00011411 |
| | | WBCnstr00019607 |
| | | WBCnstr00022871 |
| | | WBCnstr00037038 |
| | Construct_product | WBCnstr00006433 |
| | | WBCnstr00010463 |
| | | WBCnstr00037038 |
| | Microarray_results (19) |
| | Expression_cluster | WBPaper00028788:MPK-1_Response_Weak |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:germline-precursors_blastula-embryo_expressed |
| | | WBPaper00037950:hypodermis_L1-larva_expressed |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045417:128Q-huntingtin_downreglated |
| | | WBPaper00045521:Oogenic |
| | | WBPaper00045729:gld-2(RNAi)_downregulated |
| | | WBPaper00045974:NSM_enriched_totalRNA_RNAseq |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049498:npr-1(ur89)_regulated_3 |
| | | WBPaper00049942:hsf-1(RNAi)_upregulated |
| | | WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult |
| | | WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult |
| | | WBPaper00050488:20C_vs_25C_regulated_N2_adult |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050726:OsmoticStress_regulated_NoFood |
| | | WBPaper00050990:intestine_enriched |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051558:fog-2(q71)_regulated |
| | | WBPaper00052884:emb-4(hc60)_downregulated |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053295:lin-22(ot269)_upregulated |
| | | WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq |
| | | WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq |
| | | WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq |
| | | WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq |
| | | WBPaper00053321:PGCs_depleted_NuGen |
| | | WBPaper00053599:female_vs_male_upregulated |
| | | WBPaper00053599:mitosis_vs_meiosis_downregulated |
| | | WBPaper00053599:oocyte_vs_mitosis_downregulated |
| | | WBPaper00053664:ins-11(tm1053)_upregulated |
| | | WBPaper00053814:25C_downregulated_PY79 |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_upregulated |
| | | WBPaper00055354:Rifampicin-Psora_upregulated |
| | | WBPaper00055648:male-vas-deferens_expressed |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056284:ints-6(t1903)_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00057288:iff-1(RNAi)_downregulated_transcript |
| | | WBPaper00058691:sin-3(tm1276)_upregulated |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060764:swsn-1(os22ts)_downregulated |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061007:HB101_downregulated |
| | | WBPaper00061007:S.aquatilis_downregulated |
| | | WBPaper00061203:let-418(n3536)_downregulated |
| | | WBPaper00061340:ALA |
| | | WBPaper00061340:Glia |
| | | WBPaper00061340:mc2 |
| | | WBPaper00061340:Pharyngeal_intestinal_valve |
| | | WBPaper00061340:Pharyngeal_marginal_cell |
| | | WBPaper00061341:28C_48h_downregulated |
| | | WBPaper00061527:chd-7_16664-jmjd-3.1 |
| | | WBPaper00061651:ASI_enriched |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062456:doxycycline_downregulated_CB4856_transcript |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00065258:anchor-cell_enriched |
| | | WBPaper00065841:55_0 |
| | | WBPaper00065841:139_0 |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066110:Doxorubicin_downregulated_diploid |
| | | cgc4489_group_5 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00031003:24hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00032062:age_regulated_genes |
| | | WBPaper00035905:FBF-1_Associated |
| | | WBPaper00036123:Cadmium_regulated |
| | | WBPaper00036286:Pattern_H |
| | | WBPaper00040963:Q100_down |
| | | WBPaper00040963:Q200_down |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041906:I-3690_vs_OP50_3d |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00045263:0.1mM-paraquat_upregulated |
| | | WBPaper00045263:isp-1(qm150)_upregulated |
| | | WBPaper00045263:nuo-6(qm200)_upregulated |
| | | WBPaper00045263:ProLongevity-mtROS_upregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00050538:Fasting_upregulated |
| | | WBPaper00050538:Fasting_upregulated_cholesterol-dependent |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | | [cgc5767]:cluster_31 |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_E_pi(23_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_ME |
| | | [cgc6390]:mixed_oogenesis-somatic |
| | Interaction (62) |
| Map_info | Map | II | Position | -16.2721 | Error | 0.158173 |
| | Positive | Positive_clone | C23H3 | Inferred_automatically | From CDS info |
| | | | | | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 797 |
| | | | 2632 |
| | | | 7078 |
| | | | 7112 |
| | | Multi_point | 743 |
| | | | 1060 |
| | | | 1674 |
| | | | 3907 |
| | | | 4244 |
| | | Pos_neg_data | 4724 |
| Reference (25) |
| Remark | Sequence connection from [Hanna-Rose W, Han M] |
| | cog-4 added as an other name. krb 04/03/02 |
| Method | Gene |
