WormBase Tree Display for Gene: WBGene00001320

WBGene00001320 Evidence: Accession_evidence: EMBL AF435979
  SMap: S_parent: Sequence: ZK809
  Identity: Version: 1
    Name: CGC_name: ent-1 Person_evidence: WBPerson1318
      Sequence_name: ZK809.4
      Molecular_name: ZK809.4a
        ZK809.4a.1
        CE31754
        ZK809.4c
        CE45948
        ZK809.4c.1
      Other_name: CELE_ZK809.4 Accession_evidence: NDB BX284604
      Public_name: ent-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ent
    Allele (20)
    Strain: WBStrain00031603
    RNASeq_FPKM (74)
    GO_annotation: 00008666
      00008667
      00008668
      00008669
      00008670
      00008671
      00108567
      00108568
      00108569
    Ortholog (53)
    Paralog: WBGene00017532 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010701 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00008123 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009686 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010510 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009499 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: ent-1 encodes a predicted equilibrative nucleoside transporter 1 that affects growth. Paper_evidence: WBPaper00004651
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Located in plasma membrane. Expressed in intestine; isthmus; metacorpus; procorpus; and terminal bulb. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A2 (solute carrier family 29 member 2) and SLC29A3 (solute carrier family 29 member 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111278 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23096)
  Molecular_info: Corresponding_CDS: ZK809.4a
      ZK809.4c
    Corresponding_CDS_history: ZK809.4:wp84
    Corresponding_transcript: ZK809.4a.1
      ZK809.4c.1
    Other_sequence (15)
    Associated_feature: WBsf652239
      WBsf652240
      WBsf976978
      WBsf976979
      WBsf976980
      WBsf976981
      WBsf976982
      WBsf976983
      WBsf976984
      WBsf230910
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr3055
      Expr1014362
      Expr1030805
      Expr1163149
      Expr2011323
      Expr2029559
    Drives_construct: WBCnstr00011104
      WBCnstr00036999
    Construct_product: WBCnstr00011104
      WBCnstr00036999
    Microarray_results (20)
    Expression_cluster: WBPaper00005700:transmembrane_protein
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032528:L3_enriched
      WBPaper00033070:Elbe_downregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045971:tunicamycin_upregulated_control
      WBPaper00048762:FOG-3_associated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00054191:H3.3(null)_L1_upregulated
      WBPaper00054792:FOG-3_interacting
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059440:LAG-1_activated_4hr-auxin
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059763:neuron_expressed
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061527:cids-2_2203-attf-2_2451
      WBPaper00061527:puf-3-oma-2_18268
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064502:spe-44(fx110)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065623:2
      WBPaper00065623:3
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00025032:cluster_3
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00032948:FedUp
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_B
      WBPaper00037611:GLD-2-associated
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00049311:Ag-MNP_regulated
      WBPaper00049311:AgNO3_regulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_3
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(66_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
    Interaction (111)
  Map_info: Map: IV Position: 5.12916 Error: 0.006989
    Positive: Positive_clone: ZK809 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4289
        4445
    Pseudo_map_position
  Reference: WBPaper00011438
    WBPaper00011649
    WBPaper00018608
    WBPaper00024337
    WBPaper00025143
    WBPaper00034757
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene