WormBase Tree Display for Gene: WBGene00001362
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| WBGene00001362 | SMap | S_parent | Sequence | C46E1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | exc-1 | Paper_evidence | WBPaper00049851 | |||||
| Person_evidence | WBPerson1052 | ||||||||
| Sequence_name | C46E1.3 | ||||||||
| Molecular_name | C46E1.3 | ||||||||
| C46E1.3.1 | |||||||||
| CE34758 | |||||||||
| Other_name | CELE_C46E1.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | exc-1 | ||||||||
| DB_info | Database | NDB | locus_tag | CELE_C46E1.3 | |||||
| Panther | gene | CAEEL|WormBase=WBGene00001362|UniProtKB=Q7YTQ6 | |||||||
| family | PTHR14143 | ||||||||
| NCBI | gene | 181635 | |||||||
| RefSeq | protein | NM_001029303.2 | |||||||
| TREEFAM | TREEFAM_ID | TF331897 | |||||||
| TrEMBL | UniProtAcc | Q7YTQ6 | |||||||
| UniProt_GCRP | UniProtAcc | Q7YTQ6 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 06 Jul 2017 10:48:52 | WBPerson2970 | Event | Acquires_merge | WBGene00008116 | ||||
| Name_change | Sequence_name | C46E1.3 | |||||||
| Acquires_merge | WBGene00008116 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | exc | ||||||||
| Allele (117) | |||||||||
| Possibly_affected_by | WBVar02154075 | ||||||||
| Legacy_information | [Buechner M] exc for excretory canal defect. Large vacuoles appear randomly along the excretory canal, especially at the tips. 100% penetrant. Often visible by low-power microscopy. | ||||||||
| [C.elegansII] rh26 : excretory canal defect. Large vacuoles appear randomly along the excretory canal, especially at the tips. 100% penetrant. Often visible by low-power microscopy. NA1. [NJ] | |||||||||
| Strain | WBStrain00047382 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00082597 | ||||||||
| 00106092 | |||||||||
| 00106093 | |||||||||
| 00108617 | |||||||||
| 00108618 | |||||||||
| Ortholog (27) | |||||||||
| Structured_description | Concise_description | exc-1 was identified in screens for mutations that result in abnormal excretory canals; exc-1 is defined by a single allele, rh26, that produces focal, spherical cysts that are flanked by normal canals and frequently lie near the canal ending; genetic epistasis analyses suggests that exc-1 functions downstream of exc-9, and together with exc-5, in a pathway that activates CDC-42 at the canal apical surface to maintain normal apical cytoskeletal morphology. | Paper_evidence | WBPaper00003721 | |||||
| WBPaper00031650 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 02 Mar 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTP binding activity. Involved in epithelial cell development and regulation of tube size. Predicted to be located in membrane. Expressed in amphid sheath cell and excretory canal. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C46E1.3 | |||||||
| Corresponding_transcript | C46E1.3.1 | ||||||||
| Other_sequence (12) | |||||||||
| Associated_feature | WBsf671378 | ||||||||
| WBsf1008230 | |||||||||
| WBsf1024597 | |||||||||
| WBsf1024598 | |||||||||
| WBsf238327 | |||||||||
| Experimental_info | Expr_pattern | Expr13002 | |||||||
| Expr15547 | |||||||||
| Expr1020777 | |||||||||
| Expr1146577 | |||||||||
| Expr2001681 | |||||||||
| Expr2019909 | |||||||||
| Drives_construct | WBCnstr00033224 | ||||||||
| WBCnstr00038136 | |||||||||
| Construct_product | WBCnstr00033224 | ||||||||
| WBCnstr00038135 | |||||||||
| Microarray_results (13) | |||||||||
| Expression_cluster (69) | |||||||||
| Interaction | WBInteraction000550383 | ||||||||
| Map_info | Map | X | Position | 22.6968 | |||||
| Positive | Positive_clone | C46E1 | Paper_evidence | ||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 2112 | |||||||
| 2113 | |||||||||
| 2114 | |||||||||
| 3278 | |||||||||
| 3282 | |||||||||
| Pos_neg_data (21) | |||||||||
| Reference (17) | |||||||||
| Remark | [171016 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (22.6968) | ||||||||
| Method | Gene |
