WormBase Tree Display for Gene: WBGene00001413

WBGene00001413 SMap: S_parent: Sequence: C01F6
  Identity: Version: 1
    Name: CGC_name: fem-3 Person_evidence: WBPerson261
      Sequence_name: C01F6.4
      Molecular_name: C01F6.4a
        C01F6.4a.1
        CE02953
        C01F6.4c
        CE46813
        C01F6.4b
        C01F6.4c.1
      Other_name: CELE_C01F6.4 Accession_evidence: NDB BX284604
      Public_name: fem-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fem
    Reference_allele: WBVar00144465
      WBVar00240985
    Allele (71)
    Legacy_information: Class 1 (loss-of-function) : e1996sd mat : XO animals transformed into fertile females if mother homozygous e1996 into intersexes if mother heterozygous e1996/+; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. NA > 20 (e1950 e2006ts : XX self-fertile at 20x).
      Class 2 (gain-of-function) : q20sd ts : at 25x XX germline makes only sperm at 15x XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. NA9 (q24 etc. : all ts).
      See also e1950, e1980, e1981, e1983, e1984, e1995, e1996, e1999, e2004, e2006, e2007, e2010, e2043, e2045, e2062, e2063, e2068, e2070, e2143, e2178, e2289, e2353, e2354, e2366
      [C.elegansII] e1996sd,mat,och : XO animals transformed into fertile females if mother homozygous, into intersexes if mother heterozygous; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. OA>20 e1950, e2068amb, e2006ts (XX self-fertile at 20C). Also gf,ts alleles, q20sd,ts (at 25C XX germline makes only sperm, at 15C XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. OA8(gf):q22ts (weaker), q95ts (strongest allele, 80% Mog even at 15C). Cloned: 1.7 kb and 1.55 kb (minor) transcripts, former encodes predicted 388 aa novel protein. gf alleles are alterations in 3'UTR. Transgene overexpression of fem-3 leads to extensive masculinization of XX soma. [Hodgkin 1986; Ahringer et al. 1992; CB; JK; AS]
    Strain (12)
    RNASeq_FPKM (74)
    GO_annotation (26)
    Ortholog (21)
    Structured_description: Concise_description: fem-3 encodes a novel protein that promotes male development in all tissues. Paper_evidence: WBPaper00001378
          Curator_confirmed: WBPerson1843
          Date_last_updated: 11 Apr 2005 00:00:00
      Automated_description: Enables protein phosphatase binding activity. Involved in several processes, including protein localization to chromatin; regulation of reproductive process; and sex determination. Located in cytoplasm and protein-containing complex. Expressed in germ line; spermatid; and in male. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C01F6.4a
      C01F6.4c
    Corresponding_transcript: C01F6.4b
      C01F6.4a.1
      C01F6.4c.1
    Other_sequence: X64962
      CBC07169_1
    Associated_feature: WBsf660472
      WBsf997355
      WBsf1017925
      WBsf228786
  Experimental_info: RNAi_result: WBRNAi00061018 Inferred_automatically: RNAi_primary
      WBRNAi00030242 Inferred_automatically: RNAi_primary
      WBRNAi00039313 Inferred_automatically: RNAi_primary
      WBRNAi00087453 Inferred_automatically: RNAi_primary
      WBRNAi00007588 Inferred_automatically: RNAi_primary
      WBRNAi00081939 Inferred_automatically: RNAi_primary
      WBRNAi00081938 Inferred_automatically: RNAi_primary
      WBRNAi00085808 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1382
      Expr3829
      Expr9317
      Expr1021877
      Expr1030847
      Expr1143426
      Expr2011751
      Expr2029989
    Drives_construct: WBCnstr00011680
      WBCnstr00018576
      WBCnstr00036963
    Construct_product (17)
    Antibody: WBAntibody00002227
      WBAntibody00002344
    Microarray_results (21)
    Expression_cluster (154)
    Interaction (421)
    WBProcess: WBbiopr:00000110
  Map_info: Map: IV Position: 4.04953 Error: 0.001985
    Well_ordered
    Positive: Inside_rearr: eDf18
        eDf19
      Positive_clone: C01F6 Inferred_automatically: From sequence, transcript, pseudogene data
        JK#2
    Mapping_data: 2_point: 1640
      Multi_point (14)
      Pos_neg_data: 959
        964
        972
    Landmark_gene
  Reference: WBPaper00000794
    WBPaper00000922
    WBPaper00000923
    WBPaper00000943
    WBPaper00000944
    WBPaper00001013
    WBPaper00001028
    WBPaper00001037
    WBPaper00001053
    WBPaper00001077
    WBPaper00001112
    WBPaper00001116
    WBPaper00001171
    WBPaper00001206
    WBPaper00001208
    WBPaper00001224
    WBPaper00001242
    WBPaper00001266
    WBPaper00001270
    WBPaper00001279
    WBPaper00001378
    WBPaper00001416
    WBPaper00001473
    WBPaper00001475
    WBPaper00001513
    WBPaper00001544
    WBPaper00001553
    WBPaper00001554
    WBPaper00001560
    WBPaper00001609
    WBPaper00001612
    WBPaper00001629
    WBPaper00001649
    WBPaper00001683
    WBPaper00001687
    WBPaper00001691
    WBPaper00001710
    WBPaper00001743
    WBPaper00001748
    WBPaper00001772
    WBPaper00001822
    WBPaper00001824
    WBPaper00001837
    WBPaper00001842
    WBPaper00001867
    WBPaper00001883
    WBPaper00001884
    WBPaper00001898
    WBPaper00001936
    WBPaper00001966
    WBPaper00001972
    WBPaper00001977
    WBPaper00001982
    WBPaper00002006
    WBPaper00002009
    WBPaper00002060
    WBPaper00002074
    WBPaper00002131
    WBPaper00002199
    WBPaper00002206
    WBPaper00002207
    WBPaper00002278
    WBPaper00002342
    WBPaper00002383
    WBPaper00002446
    WBPaper00002493
    WBPaper00002504
    WBPaper00002519
    WBPaper00002548
    WBPaper00002550
    WBPaper00002580
    WBPaper00002631
    WBPaper00002644
    WBPaper00002649
    WBPaper00002662
    WBPaper00002933
    WBPaper00002949
    WBPaper00003026
    WBPaper00003047
    WBPaper00003144
    WBPaper00003175
    WBPaper00003178
    WBPaper00003271
    WBPaper00003279
    WBPaper00003323
    WBPaper00003371
    WBPaper00003372
    WBPaper00003402
    WBPaper00003410
    WBPaper00003569
    WBPaper00003597
    WBPaper00003630
    WBPaper00003692
    WBPaper00003744
    WBPaper00003933
    WBPaper00003942
    WBPaper00003968
    WBPaper00003990
    WBPaper00004113
    WBPaper00004129
    WBPaper00004220
    WBPaper00004229
    WBPaper00004256
    WBPaper00004349
    WBPaper00004396
    WBPaper00004448
    WBPaper00004527
    WBPaper00004549
    WBPaper00004592
    WBPaper00004755
    WBPaper00004935
    WBPaper00005002
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    WBPaper00005198
    WBPaper00005237
    WBPaper00005265
    WBPaper00005292
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    WBPaper00005379
    WBPaper00005549
    WBPaper00005566
    WBPaper00005602
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    WBPaper00005643
    WBPaper00005670
    WBPaper00005710
    WBPaper00005820
    WBPaper00006019
    WBPaper00006094
    WBPaper00006101
    WBPaper00006197
    WBPaper00006390
    WBPaper00010105
    WBPaper00010313
    WBPaper00010806
    WBPaper00011247
    WBPaper00011523
    WBPaper00011628
    WBPaper00011631
    WBPaper00012340
    WBPaper00012402
    WBPaper00012446
    WBPaper00012490
    WBPaper00012570
    WBPaper00012585
    WBPaper00012589
    WBPaper00012610
    WBPaper00012665
    WBPaper00012683
    WBPaper00012697
    WBPaper00012732
    WBPaper00012742
    WBPaper00013704
    WBPaper00013707
    WBPaper00013762
    WBPaper00013780
    WBPaper00013845
    WBPaper00013929
    WBPaper00013937
    WBPaper00013946
    WBPaper00014253
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    WBPaper00014441
    WBPaper00014490
    WBPaper00014549
    WBPaper00014708
    WBPaper00014817
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    WBPaper00014928
    WBPaper00014947
    WBPaper00015013
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    WBPaper00015240
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    WBPaper00015714
    WBPaper00016276
    WBPaper00016316
    WBPaper00016411
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    WBPaper00016504
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    WBPaper00016562
    WBPaper00016815
    WBPaper00017060
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    WBPaper00017116
    WBPaper00017345
    WBPaper00017483
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    WBPaper00017942
    WBPaper00018093
    WBPaper00018372
    WBPaper00018387
    WBPaper00018394
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    WBPaper00018399
    WBPaper00018405
    WBPaper00018654
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    WBPaper00018705
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    WBPaper00018722
    WBPaper00018727
    WBPaper00018743
    WBPaper00018774
    WBPaper00018879
    WBPaper00018891
    WBPaper00019558
    WBPaper00019619
    WBPaper00019680
    WBPaper00020778
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    WBPaper00020860
    WBPaper00020975
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    WBPaper00020990
    WBPaper00021044
    WBPaper00021052
    WBPaper00021080
    WBPaper00021121
    WBPaper00021780
    WBPaper00021869
    WBPaper00021980
    WBPaper00022032
    WBPaper00022117
    WBPaper00022215
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    WBPaper00022608
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    WBPaper00062388
    WBPaper00063266
    WBPaper00063267
    WBPaper00063322
    WBPaper00063954
    WBPaper00065011
    WBPaper00065699
    WBPaper00065859
    WBPaper00065929
    WBPaper00066170
  Picture: WBPicture0000013095
  Method: Gene