WormBase Tree Display for Gene: WBGene00001593
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| WBGene00001593 | SMap | S_parent | Sequence | ZC317 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | glc-3 | Person_evidence | WBPerson32 | |||||
| Sequence_name | ZC317.3 | ||||||||
| Molecular_name | ZC317.3 | ||||||||
| ZC317.3.1 | |||||||||
| CE28159 | |||||||||
| Other_name | CELE_ZC317.3 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | glc-3 | ||||||||
| DB_info | Database | AceView | gene | 5F928 | |||||
| WormQTL | gene | WBGene00001593 | |||||||
| WormFlux | gene | WBGene00001593 | |||||||
| NDB | locus_tag | CELE_ZC317.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001593|UniProtKB=G5EEZ3 | |||||||
| family | PTHR18945 | ||||||||
| NCBI | gene | 178930 | |||||||
| RefSeq | protein | NM_072040.7 | |||||||
| TrEMBL | UniProtAcc | G5EEZ3 | |||||||
| UniProt_GCRP | UniProtAcc | G5EEZ3 | |||||||
| OMIM | gene | 138491 | |||||||
| 305990 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | glc | ||||||||
| Allele (77) | |||||||||
| Strain | WBStrain00003302 | ||||||||
| WBStrain00031369 | |||||||||
| WBStrain00040635 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (45) | |||||||||
| Paralog (100) | |||||||||
| Structured_description | Concise_description | glc-3 encodes an L-glutamate-gated chloride channel subunit; GLC-3 is sensitive to fipronil and BIDN, but picrotoxinin-insensitive; GLC-3 is expressed in the AIY interneuron. | Paper_evidence | WBPaper00004607 | |||||
| WBPaper00024232 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 02 Sep 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Involved in locomotion involved in locomotory behavior; sensory perception of chemical stimulus; and sensory processing. Predicted to be located in neuron projection and synapse. Expressed in M4 neuron; head ganglion; and tail neurons. Human ortholog(s) of this gene implicated in hyperekplexia 1 and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of human GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRA3 (glycine receptor alpha 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070422 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4327) | ||||
| DOID:0060696 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4326) | ||||||
| Molecular_info | Corresponding_CDS | ZC317.3 | |||||||
| Corresponding_transcript | ZC317.3.1 | ||||||||
| Other_sequence (31) | |||||||||
| Associated_feature | WBsf668950 | ||||||||
| WBsf668951 | |||||||||
| WBsf1000006 | |||||||||
| WBsf1000007 | |||||||||
| WBsf1019634 | |||||||||
| WBsf1019635 | |||||||||
| WBsf233679 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00030288 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00021651 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058833 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr7157 | ||||||||
| Expr10073 | |||||||||
| Expr12054 | |||||||||
| Expr15365 | |||||||||
| Expr15923 | |||||||||
| Expr15925 | |||||||||
| Expr1016872 | |||||||||
| Expr1162269 | |||||||||
| Expr2012081 | |||||||||
| Expr2030317 | |||||||||
| Drives_construct | WBCnstr00003773 | ||||||||
| WBCnstr00015045 | |||||||||
| WBCnstr00036839 | |||||||||
| WBCnstr00042608 | |||||||||
| Construct_product (11) | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction (20) | |||||||||
| Map_info | Map | V | Position | -1.89496 | Error | 0.015231 | |||
| Positive | Positive_clone | ZC317 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4348 | |||||||
| Pseudo_map_position | |||||||||
| Reference (24) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
