WormBase Tree Display for Gene: WBGene00001696
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| WBGene00001696 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F46H5 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | grd-7 | Person_evidence | WBPerson83 | |||||
| Sequence_name | F46H5.6 | ||||||||
| Molecular_name | F46H5.6 | ||||||||
| F46H5.6.1 | |||||||||
| CE10614 | |||||||||
| Other_name | CELE_F46H5.6 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | grd-7 | ||||||||
| DB_info | Database | AceView | gene | XH886 | |||||
| WormQTL | gene | WBGene00001696 | |||||||
| WormFlux | gene | WBGene00001696 | |||||||
| NDB | locus_tag | CELE_F46H5.6 | |||||||
| NCBI | gene | 191661 | |||||||
| RefSeq | protein | NM_076823.5 | |||||||
| TREEFAM | TREEFAM_ID | TF316390 | |||||||
| TrEMBL | UniProtAcc | Q3Y407 | |||||||
| UniProt_GCRP | UniProtAcc | Q3Y407 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 18 Jul 2018 16:19:08 | WBPerson1983 | Event | Split_into | WBGene00303398 | ||||
| Split_into | WBGene00303398 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele (41) | |||||||||
| Strain | WBStrain00033131 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00080704 | ||||||||
| 00080705 | |||||||||
| 00080706 | |||||||||
| 00080707 | |||||||||
| 00080708 | |||||||||
| Ortholog (13) | |||||||||
| Paralog (30) | |||||||||
| Structured_description | Concise_description | grd-7 encodes a hedgehog-like protein, with an N-terminal DUF271 domain,a central low-complexity proline-rich domain, and a C-terminal Ground(Grd) domain; GRD-7 is expressed in three to four posterior DA motorneurons of the ventral nerve cord; the Ground domain is predicted toform a cysteine-crosslinked protein involved in intercellularsignalling, and it has subtle similarity to the N-terminal Hedge domainof HEDGEHOG proteins; GRD-7 is weakly required for normal molting; GRD-7is also required for normal growth to full size, cuticle adhesion,locomotion, and vulval morphogenesis; all of these requirements mayreflect common defects in cholesterol-dependent hedgehog-like signallingor in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||||
| WBPaper00003717 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable signaling receptor binding activity. Predicted to be involved in cell communication. Predicted to be located in extracellular region. Expressed in seam cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F46H5.6 | |||||||
| Corresponding_CDS_history | F46H5.6:wp133 | ||||||||
| F46H5.6:wp204 | |||||||||
| F46H5.6:wp266 | |||||||||
| Corresponding_transcript | F46H5.6.1 | ||||||||
| Other_sequence | AS01157 | ||||||||
| AS01829 | |||||||||
| AS00174 | |||||||||
| JO473146.1 | |||||||||
| Associated_feature | WBsf654124 | ||||||||
| WBsf670714 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00076996 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00047583 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032397 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077020 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr638 | ||||||||
| Expr4433 | |||||||||
| Expr1016250 | |||||||||
| Expr1151420 | |||||||||
| Expr2012237 | |||||||||
| Expr2030473 | |||||||||
| Drives_construct | WBCnstr00011996 | ||||||||
| WBCnstr00012462 | |||||||||
| WBCnstr00036760 | |||||||||
| Construct_product | WBCnstr00036760 | ||||||||
| Microarray_results (14) | |||||||||
| Expression_cluster (68) | |||||||||
| Interaction | WBInteraction000454627 | ||||||||
| WBInteraction000523707 | |||||||||
| WBInteraction000546242 | |||||||||
| WBInteraction000546430 | |||||||||
| WBInteraction000546604 | |||||||||
| WBInteraction000546814 | |||||||||
| WBInteraction000548120 | |||||||||
| WBInteraction000548121 | |||||||||
| WBInteraction000548122 | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | X | Position | -1.78652 | Error | 0.001722 | |||
| Positive | Positive_clone | F46H5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002823 | ||||||||
| WBPaper00003717 | |||||||||
| WBPaper00011801 | |||||||||
| WBPaper00024393 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00064105 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
