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WormBase Tree Display for Gene: WBGene00001727

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Name Class

WBGene00001727EvidencePaper_evidenceWBPaper00003717
SMapS_parentSequenceT05C3
IdentityVersion1
NameCGC_namegrl-18Person_evidenceWBPerson83
Sequence_nameT05C3.4
Molecular_nameT05C3.4
T05C3.4.1
CE39030
Other_nameCELE_T05C3.4Accession_evidenceNDBBX284605
Public_namegrl-18
DB_infoDatabaseAceViewgene5F960
WormQTLgeneWBGene00001727
WormFluxgeneWBGene00001727
NDBlocus_tagCELE_T05C3.4
PanthergeneCAEEL|WormBase=WBGene00001727|UniProtKB=O16301
familyPTHR23261
NCBIgene353441
RefSeqproteinNM_182425.4
TREEFAMTREEFAM_IDTF315611
TrEMBLUniProtAccO16301
UniProt_GCRPUniProtAccO16301
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgrl
Allele (54)
StrainWBStrain00032819
RNASeq_FPKM (74)
Ortholog (15)
Paralog (32)
Structured_descriptionConcise_descriptiongrl-18 encodes a hedgehog-like protein, with an N-terminal signalsequence, a central proline-rich region, and a C-terminal Ground-like(Grl) domain; the Grl domain is predicted to form a cysteine-crosslinkedprotein involved in intercellular signalling, and it has subtlesimilarity to the N-terminal Hedge domain of HEDGEHOG proteins.Paper_evidenceWBPaper00003717
WBPaper00026841
WBPaper00027263
Curator_confirmedWBPerson567
Date_last_updated05 Nov 2006 00:00:00
Automated_descriptionEnriched in GABAergic neurons and accessory cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and let-60 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST05C3.4
Corresponding_CDS_historyT05C3.4:wp93
T05C3.4:wp105
T05C3.4:wp147
Corresponding_transcriptT05C3.4.1
Other_sequenceACC28335_1
FC552751.1
Associated_featureWBsf652627
WBsf668952
WBsf1019651
Experimental_infoRNAi_resultWBRNAi00052500Inferred_automaticallyRNAi_primary
WBRNAi00018223Inferred_automaticallyRNAi_primary
Expr_patternExpr4457
Expr1015793
Expr1156124
Expr2012252
Expr2030488
Drives_constructWBCnstr00012022
WBCnstr00036734
Construct_productWBCnstr00036734
Microarray_results (13)
Expression_cluster (73)
InteractionWBInteraction000343948
WBInteraction000346767
Map_infoMapVPosition-1.81907Error0.010657
PositivePositive_cloneT05C3Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00003717
WBPaper00028754
WBPaper00031588
WBPaper00063715
WBPaper00064105
WBPaper00065979
Remarkground-like gene, contains ground-like domain, hedgehog-relatedPaper_evidenceWBPaper00003717
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene