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WormBase Tree Display for Gene: WBGene00001803

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Name Class

WBGene00001803EvidenceCGC_data_submission
SMapS_parentSequenceC14F11
IdentityVersion2
NameCGC_namelite-1Person_evidenceWBPerson522
WBPerson423
Sequence_nameC14F11.3
Molecular_nameC14F11.3
C14F11.3.1
CE29579
Other_namegur-2Person_evidenceWBPerson522
CELE_C14F11.3Accession_evidenceNDBBX284606
Public_namelite-1
DB_infoDatabaseAceViewgeneXG846
WormQTLgeneWBGene00001803
WormFluxgeneWBGene00001803
NDBlocus_tagCELE_C14F11.3
PanthergeneCAEEL|WormBase=WBGene00001803|UniProtKB=Q17990
familyPTHR21143
NCBIgene180894
RefSeqproteinNM_076642.7
SwissProtUniProtAccQ17990
TREEFAMTREEFAM_IDTF321557
UniProt_GCRPUniProtAccQ17990
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
202 Feb 2007 10:20:45WBPerson2970Name_changeCGC_namelite-1
Other_namegur-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlite
AlleleWBVar02157529Inferred_automaticallyFrom strain object: TQ8245
WBVar02158550
WBVar02158552
WBVar02158555
WBVar02044987
WBVar00054012
WBVar00603903
WBVar00603904
WBVar00054017
WBVar00054022
WBVar00054027
WBVar01820081
WBVar01820082
WBVar00054032
WBVar00054037
WBVar00054042
WBVar00054047
WBVar00091817
WBVar00054052
WBVar00054057
WBVar02150907
WBVar00054062
WBVar00299147
WBVar00299148
WBVar00054067
WBVar00054072
WBVar01469258
WBVar01469259
WBVar01469262
WBVar01526556
WBVar02146896
WBVar02116433
WBVar01639752
WBVar00079704
WBVar00079705
WBVar00505650
WBVar00079706
WBVar00505651
WBVar00079707
WBVar00505652
WBVar01815719
WBVar00505653
WBVar00079709
WBVar00505654
WBVar00505655
WBVar00505656
WBVar00505657
WBVar01496840
WBVar00505658
WBVar00505659
WBVar00505660
WBVar01498684
WBVar00505661
WBVar00505662
WBVar00505663
WBVar01493729
WBVar01152804
WBVar01152805
WBVar01152806
WBVar01152807
WBVar01152808
WBVar01152809
WBVar01152810
WBVar00296276
WBVar00261434
WBVar01152811
WBVar01152812
WBVar01152813
WBVar01152814
WBVar01152815
WBVar01152816
WBVar01152817
WBVar01152818
WBVar01881028
WBVar01152820
WBVar01881029
WBVar01152821
WBVar01881030
WBVar01881031
WBVar01152822
WBVar01152823
WBVar01881032
WBVar01881033
WBVar01881034
WBVar01881035
WBVar01881036
WBVar01881037
WBVar01881038
WBVar01881039
WBVar01661407
WBVar01881040
WBVar01881041
WBVar01881042
WBVar01926925
WBVar00264776
WBVar00053987
WBVar00053992
WBVar00053997
WBVar00032871
WBVar01490306
WBVar00054002
WBVar00032876
WBVar00054007
WBVar01500067
Strain (40)
RNASeq_FPKM (74)
GO_annotation (28)
Ortholog (30)
ParalogWBGene00001211Caenorhabditis elegansFrom_analysisPanther
WBGene00001804Caenorhabditis elegansFrom_analysisTreeFam
Panther
Structured_descriptionConcise_descriptionlite-1 encodes a eight-transmembrane protein that is a member of the invertebrate family of Gustatory receptors; LITE-1 functions in neurons as an ultraviolet light receptor required for proper avoidance (photophobic) response to short-wavelength light; ectopic expression of LITE-1 in other tissues, namely body wall and vulval muscles, is sufficient to confer light-responsive muscle contraction; genetic analyses indicate that LITE-1 can stimulate locomotion independent of G protein signaling, as LITE-1 can induce locomotion in near-paralyzed synaptic signaling mutants; further, site of action studies indicate that LITE-1 functions in one or more tail neurons to mediate this light-activated forward locomotion; rescuing LITE-1::GFP fusion proteins reveal expression in the PVT and AVG neurons.Paper_evidenceWBPaper00032087
Curator_confirmedWBPerson1843
Date_last_updated11 Aug 2008 00:00:00
Automated_descriptionEnables blue light photoreceptor activity. Involved in locomotory behavior and response to light stimulus. Located in neuron projection; neuronal cell body; and plasma membrane. Expressed in ganglia; hyp3; and pharyngeal neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC14F11.3
Corresponding_transcriptC14F11.3.1
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00040557Inferred_automaticallyRNAi_primary
WBRNAi00028898Inferred_automaticallyRNAi_primary
WBRNAi00010762Inferred_automaticallyRNAi_primary
WBRNAi00000949Inferred_automaticallyRNAi_primary
Expr_patternExpr12196
Expr12672
Expr1025219
Expr1144612
Expr2013229
Expr2031460
Drives_constructWBCnstr00000264
WBCnstr00020588
WBCnstr00020589
WBCnstr00020590
WBCnstr00036676
Construct_productWBCnstr00000262
WBCnstr00000264
WBCnstr00020587
WBCnstr00020589
WBCnstr00020590
WBCnstr00036676
AntibodyWBAntibody00002718
WBAntibody00002719
Microarray_results (18)
Expression_cluster (156)
InteractionWBInteraction000285492
WBInteraction000375497
WBInteraction000404186
WBInteraction000408973
WBInteraction000438074
WBProcessWBbiopr:00000055
Map_infoMapXPosition-3.37427Error0.03205
PositivePositive_cloneC14F11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4387
4420
Pseudo_map_position
Reference (44)
Remark[Hugh M Robertson].I've recognized five C. elegans genes as members of a large family of gustatory receptors (about 60 total) in the Drosophila genome originally described by John Carlson's laboratory. Phylogenetically they form three distinct lineages within this family, indicating that the family predates the nematode/arthropod split. In the absence of functional, mutant, or expression data, I prefer to name them in the least definitive manner possibl, but indicating that they are candidate receptors (seven-TM superfamily) related to the gustatory receptors of Drosophila.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene