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WormBase Tree Display for Gene: WBGene00001841

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Name Class

WBGene00001841EvidenceCGC_data_submission
SMapS_parentSequenceC36B7
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classhen
Allele (200)
StrainWBStrain00022193
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (11)
ParalogWBGene00020505Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionhen-1 encodes a secreted protein that contains a low-density lipoprotein (LDL) receptor motif A; HEN-1 activity is required for integration of sensory stimuli and behavioral plasticity; a hen-1::GFP reporter is expressed in pharyngeal muscles, the vulva, and weakly in a subset of neurons; antibodies to HEN-1 protein detect expression exclusively in the AIY and ASE neurons, where HEN-1 appears to localize to cell bodies and in a punctate pattern in nerve ring axons at sites of synapse formation; HEN-1 expression in AIY appears to be under the control of the TTX-3 LIM domain transcription factor.Paper_evidenceWBPaper00004727
WBPaper00005300
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated06 Nov 2007 00:00:00
Automated_descriptionPredicted to enable transmembrane receptor protein tyrosine kinase activator activity. Involved in dauer larval development and nervous system process. Located in axon and neuronal cell body. Expressed in neurons; pharyngeal muscle cell; and vulva.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC36B7.7
Corresponding_transcriptC36B7.7.1
Experimental_infoRNAi_resultWBRNAi00042048Inferred_automaticallyRNAi_primary
WBRNAi00011685Inferred_automaticallyRNAi_primary
WBRNAi00029605Inferred_automaticallyRNAi_primary
Expr_patternExpr1911
Expr1912
Expr4411
Expr1017068
Expr1146048
Expr2012397
Expr2030633
Marker48
Drives_constructWBCnstr00004840
WBCnstr00010515
WBCnstr00011976
WBCnstr00036653
Construct_productWBCnstr00036653
AntibodyWBAntibody00000523
Microarray_results (17)
Expression_cluster (165)
Interaction (24)
Anatomy_functionWBbtf0093
WBbtf0094
WBbtf0095
WBbtf0096
WBbtf0097
WBbtf0098
WBbtf0099
WBbtf0100
Map_infoMapXPosition-1.85356Error0.009919
PositivePositive_cloneC36B7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4400
Pseudo_map_position
Reference (47)
RemarkSequence connection from [Katsura I]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene