WormBase Tree Display for Gene: WBGene00001965
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| WBGene00001965 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C17C3 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | hlh-26 | Person_evidence | WBPerson346 | |||||
| Sequence_name | C17C3.8 | ||||||||
| Molecular_name | C17C3.8 | ||||||||
| C17C3.8.1 | |||||||||
| CE04028 | |||||||||
| Other_name | CELE_C17C3.8 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | hlh-26 | ||||||||
| DB_info | Database | AceView | gene | 2F822 | |||||
| WormQTL | gene | WBGene00001965 | |||||||
| WormFlux | gene | WBGene00001965 | |||||||
| NDB | locus_tag | CELE_C17C3.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001965|UniProtKB=Q18053 | |||||||
| family | PTHR10985 | ||||||||
| NCBI | gene | 173939 | |||||||
| RefSeq | protein | NM_062661.7 | |||||||
| SwissProt | UniProtAcc | Q18053 | |||||||
| TREEFAM | TREEFAM_ID | TF322171 | |||||||
| UniProt_GCRP | UniProtAcc | Q18053 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hlh | ||||||||
| Allele (21) | |||||||||
| Strain | WBStrain00032036 | ||||||||
| WBStrain00033856 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (17) | |||||||||
| Paralog | WBGene00001964 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001968 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001967 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001966 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | hlh-26 encodes a REF-1-like protein with two bHLH domains that represses lag-2 transcription in ABa descendants (in response to a Notch signal, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28) and tbx-37 transcription in EMS descendants (independently of Notch, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28); lag-2 repression by HLH-26 may require UNC-37; HLH-26's paralogs include HLH-25 through HLH-29 and (more distantly) REF-1; HLH-26 is not visibly expressed in EMS descendants, and has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00025235 | |||||
| WBPaper00031196 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 18 Apr 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ABpla; ABplp; ABpra; and ABprp. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C17C3.8 | |||||||
| Corresponding_transcript | C17C3.8.1 | ||||||||
| Associated_feature | WBsf978584 | ||||||||
| Transcription_factor | WBTranscriptionFactor000073 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00084010 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00028995 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040786 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022289 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107447 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8069 | ||||||||
| Expr10328 | |||||||||
| Expr10329 | |||||||||
| Expr1017022 | |||||||||
| Expr1144825 | |||||||||
| Expr2012501 | |||||||||
| Expr2030740 | |||||||||
| Drives_construct | WBCnstr00005216 | ||||||||
| WBCnstr00015259 | |||||||||
| WBCnstr00036555 | |||||||||
| Construct_product | WBCnstr00005216 | ||||||||
| WBCnstr00036555 | |||||||||
| Regulate_expr_cluster | WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium | ||||||||
| WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (47) | |||||||||
| Interaction (145) | |||||||||
| Map_info | Map | II | Position | -1.19632 | Error | 0.002366 | |||
| Positive | Positive_clone | C17C3 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00025235 | ||||||||
| WBPaper00027287 | |||||||||
| WBPaper00027309 | |||||||||
| WBPaper00029033 | |||||||||
| WBPaper00030887 | |||||||||
| WBPaper00031196 | |||||||||
| WBPaper00034761 | |||||||||
| WBPaper00062585 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
