WormBase Tree Display for Gene: WBGene00001978
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| WBGene00001978 | SMap | S_parent | Sequence | R13H4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hmp-1 | Person_evidence | WBPerson498 | |||||
| Sequence_name | R13H4.4 | ||||||||
| Molecular_name (19) | |||||||||
| Other_name | CELE_R13H4.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | hmp-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hmp | ||||||||
| Allele (102) | |||||||||
| Legacy_information | [C.elegansII] Mutations zygotic lethal, arrest at 1.25-1.5 fold stage with lumps in dorsal hypoderm. Cloned: encodes probable alpha-catenin homolog. [JJ] | ||||||||
| Strain | WBStrain00001826 | ||||||||
| WBStrain00022476 | |||||||||
| WBStrain00024213 | |||||||||
| WBStrain00030631 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00004804 | ||||||||
| 00004805 | |||||||||
| 00004806 | |||||||||
| 00004807 | |||||||||
| 00004808 | |||||||||
| 00004809 | |||||||||
| 00004810 | |||||||||
| 00004811 | |||||||||
| 00004812 | |||||||||
| 00004813 | |||||||||
| 00004814 | |||||||||
| 00004815 | |||||||||
| 00004816 | |||||||||
| 00049558 | |||||||||
| 00049559 | |||||||||
| 00049560 | |||||||||
| 00049561 | |||||||||
| 00049562 | |||||||||
| 00049563 | |||||||||
| 00049564 | |||||||||
| 00049565 | |||||||||
| 00049566 | |||||||||
| 00049567 | |||||||||
| 00049568 | |||||||||
| 00109828 | |||||||||
| 00109829 | |||||||||
| 00109830 | |||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00000832 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| WBGene00000942 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | hmp-1 encodes an alpha-catenin; during development, hmp-1 activity is required for proper enclosure and elongation of the embryo; HMP-1 localizes to hypodermal adherens junctions. | Paper_evidence | WBPaper00003046 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Jun 2008 00:00:00 | ||||||||
| Automated_description | Enables actin filament binding activity and beta-catenin binding activity. Involved in several processes, including cortical actin cytoskeleton organization; embryonic morphogenesis; and regulation of actin cytoskeleton organization. Located in adherens junction and apical junction complex. Part of catenin complex. Expressed in several structures, including distal tip cell; germ cell; intestinal cell; neuroblasts; and pharyngeal cell. Human ortholog(s) of this gene implicated in several diseases, including arrhythmogenic right ventricular dysplasia 13; cervix uteri carcinoma in situ; and urinary system cancer (multiple). Is an ortholog of human CTNNA2 (catenin alpha 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8991 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||
| DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
| DOID:0090131 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2510) | ||||||
| DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
| DOID:0060864 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
| DOID:0110084 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2511) | ||||||
| DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
| DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
| DOID:3457 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
| Molecular_info | Corresponding_CDS | R13H4.4a | |||||||
| R13H4.4b | |||||||||
| R13H4.4c | |||||||||
| R13H4.4d | |||||||||
| R13H4.4e | |||||||||
| R13H4.4f | |||||||||
| Corresponding_transcript | R13H4.4a.1 | ||||||||
| R13H4.4b.1 | |||||||||
| R13H4.4c.1 | |||||||||
| R13H4.4d.1 | |||||||||
| R13H4.4e.1 | |||||||||
| R13H4.4f.1 | |||||||||
| R13H4.4f.2 | |||||||||
| Other_sequence (49) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Chronogram912 | ||||||||
| Expr6534 | |||||||||
| Expr9341 | |||||||||
| Expr13047 | |||||||||
| Expr14677 | |||||||||
| Expr1011130 | |||||||||
| Expr1031148 | |||||||||
| Expr1155584 | |||||||||
| Expr2012529 | |||||||||
| Expr2030768 | |||||||||
| Drives_construct | WBCnstr00002622 | ||||||||
| WBCnstr00004619 | |||||||||
| WBCnstr00006235 | |||||||||
| WBCnstr00007873 | |||||||||
| WBCnstr00008029 | |||||||||
| WBCnstr00009117 | |||||||||
| WBCnstr00020495 | |||||||||
| WBCnstr00036545 | |||||||||
| Construct_product | WBCnstr00020495 | ||||||||
| WBCnstr00036545 | |||||||||
| Antibody | WBAntibody00000167 | ||||||||
| WBAntibody00001450 | |||||||||
| WBAntibody00002691 | |||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (135) | |||||||||
| Interaction (117) | |||||||||
| WBProcess | WBbiopr:00000017 | ||||||||
| Map_info | Map | V | Position | 3.46447 | Error | 0.012439 | |||
| Positive | Positive_clone | R13H4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4408 | |||||||
| 5036 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (108) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
