WormBase Tree Display for Gene: WBGene00002027
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| WBGene00002027 | Evidence | Paper_evidence | WBPaper00005039 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | T05F1 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | hsr-9 | |||||||
| Sequence_name | T05F1.6 | ||||||||
| Molecular_name | T05F1.6 | ||||||||
| T05F1.6.1 | |||||||||
| CE36405 | |||||||||
| Other_name | T05F1.6a/b | Paper_evidence | WBPaper00004757 | ||||||
| CELE_T05F1.6 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | hsr-9 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hsr | ||||||||
| Allele (72) | |||||||||
| Strain | WBStrain00028634 | ||||||||
| WBStrain00028637 | |||||||||
| WBStrain00028638 | |||||||||
| WBStrain00035883 | |||||||||
| WBStrain00054768 | |||||||||
| WBStrain00054766 | |||||||||
| WBStrain00054770 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00082142 | ||||||||
| 00082143 | |||||||||
| 00082144 | |||||||||
| 00082145 | |||||||||
| 00082146 | |||||||||
| 00082147 | |||||||||
| 00082148 | |||||||||
| 00082149 | |||||||||
| 00082150 | |||||||||
| Contained_in_operon | CEOP1556 | ||||||||
| Ortholog (33) | |||||||||
| Structured_description | Concise_description | hsr-9 encodes a protein containing a BRCT (BRCA 1 C terminus) domain that is found in proteins that regulate the cell cycle checkpoint in response to DNA damage; HSR-9 activity is required for a normal response to DNA damage caused by gamma-irradiation; loss of HSR-9 function via RNA-mediated interference after gamma-irradiation results in defects in mitotic cell cycle arrest, reduction of apoptosis of pachytene nuclei, and radiation sensitivity of progeny; the expression pattern and subcellular localization of HSR-9 are not yet known. | Paper_evidence | WBPaper00005039 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable histone binding activity. Predicted to be involved in DNA damage checkpoint signaling and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in germ cell. Human ortholog(s) of this gene implicated in pulmonary hypertension. Is an ortholog of human TP53BP1 (tumor protein p53 binding protein 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:6432 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11999) | ||||
| Molecular_info | Corresponding_CDS | T05F1.6 | |||||||
| Corresponding_CDS_history | T05F1.6a:wp119 | ||||||||
| T05F1.6b:wp119 | |||||||||
| Corresponding_transcript | T05F1.6.1 | ||||||||
| Other_sequence (13) | |||||||||
| Associated_feature | WBsf643601 | ||||||||
| WBsf656772 | |||||||||
| WBsf218310 | |||||||||
| WBsf218311 | |||||||||
| WBsf218312 | |||||||||
| WBsf218313 | |||||||||
| WBsf218314 | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr11818 | ||||||||
| Expr1013325 | |||||||||
| Expr1031182 | |||||||||
| Expr1156167 | |||||||||
| Expr2012632 | |||||||||
| Expr2030868 | |||||||||
| Antibody | WBAntibody00002432 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (186) | |||||||||
| Interaction (59) | |||||||||
| Map_info | Map | I | Position | 3.82639 | Error | 0.002021 | |||
| Positive | Positive_clone | T05F1 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
