WormBase Tree Display for Gene: WBGene00002031
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WBGene00002031 | SMap | S_parent | Sequence | Y34B4A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | hst-6 | Person_evidence | WBPerson1831 | |||||
Sequence_name | Y34B4A.3 | ||||||||
Molecular_name | Y34B4A.3 | ||||||||
Y34B4A.3.1 | |||||||||
CE32011 | |||||||||
Other_name | Y34B4A.e | Curator_confirmed | WBPerson1983 | ||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
CELE_Y34B4A.3 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | hst-6 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | hst | ||||||||
Allele (56) | |||||||||
Strain (3) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (11) | |||||||||
Ortholog (46) | |||||||||
Structured_description | Concise_description | hst-6 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme heparan 6O-sulfotransferase; by homology, HST-6 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C6 hydroxyl group of the glucosamine subunits; during development, hst-6 activity is required for normal body size and nervous system development; an hst-6::gfp transcriptional reporter fusion is expressed beginning at early embryonic stages and continuing through adulthood; expression in embryos is nearly ubiquitous with later expression primarily restricted to neuronal tissues. | Paper_evidence | WBPaper00006471 | |||||
WBPaper00029002 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 26 Oct 2007 00:00:00 | ||||||||
Automated_description | Predicted to enable heparan sulfate 6-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification and regulation of growth. Predicted to be located in membrane. Expressed in AIBL; AIBR; RIML; RIMR; and neurons. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome and hypogonadotropic hypogonadism 15 with or without anosmia. Is an ortholog of human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0111843 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19133) | ||||
DOID:0090075 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5201) | ||||||
Molecular_info | Corresponding_CDS | Y34B4A.3 | |||||||
Corresponding_CDS_history | Y34B4A.3:wp86 | ||||||||
Corresponding_transcript | Y34B4A.3.1 | ||||||||
Other_sequence (28) | |||||||||
Associated_feature | WBsf648093 | ||||||||
WBsf662771 | |||||||||
WBsf1005223 | |||||||||
WBsf235701 | |||||||||
Experimental_info | RNAi_result | WBRNAi00020191 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00055817 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr2901 | ||||||||
Expr12886 | |||||||||
Expr1014721 | |||||||||
Expr1031186 | |||||||||
Expr1159347 | |||||||||
Expr2012637 | |||||||||
Expr2030873 | |||||||||
Drives_construct | WBCnstr00011014 | ||||||||
WBCnstr00016152 | |||||||||
WBCnstr00036509 | |||||||||
Construct_product | WBCnstr00005444 | ||||||||
WBCnstr00005695 | |||||||||
WBCnstr00005696 | |||||||||
WBCnstr00005697 | |||||||||
WBCnstr00005699 | |||||||||
WBCnstr00005700 | |||||||||
WBCnstr00005701 | |||||||||
WBCnstr00005702 | |||||||||
WBCnstr00005703 | |||||||||
WBCnstr00036509 | |||||||||
Microarray_results (17) | |||||||||
Expression_cluster (104) | |||||||||
Interaction (12) | |||||||||
Anatomy_function | WBbtf0285 | ||||||||
Map_info | Map | X | Position | -5.86683 | Error | 0.040424 | |||
Positive | Positive_clone | Y34B4A | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4422 | |||||||
4502 | |||||||||
Pseudo_map_position | |||||||||
Reference (29) | |||||||||
Remark | Sequence connection from [Turnbull J, Kinnunen T]. krb 13/11/01 | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |