WormBase Tree Display for Gene: WBGene00002040
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| WBGene00002040 | SMap | S_parent | Sequence | F56A6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hum-7 | |||||||
| Sequence_name | F56A6.2 | ||||||||
| Molecular_name | F56A6.2a | ||||||||
| F56A6.2a.1 | |||||||||
| CE45848 | |||||||||
| F56A6.2b | |||||||||
| CE45854 | |||||||||
| F56A6.2b.1 | |||||||||
| Other_name | CELE_F56A6.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | hum-7 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hum | ||||||||
| Allele (370) | |||||||||
| Legacy_information | [Titus MA] hum: heavy chain of an unconventional myosin hum-7 encodes a class IX unconventional myosin. The tail region of this motor protein contains both a Zn-finger and a rhoGAP domain. | ||||||||
| [Baker JP, Titus MA] No mutants known. Encodes class IX unconventional myosin. Maps near bli-3, smg-2. | |||||||||
| Strain | WBStrain00037329 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (43) | |||||||||
| Paralog (21) | |||||||||
| Structured_description | Concise_description | hum-7 encodes a class IX unconventional myosin heavy chain that contains a myosin motor domain in the head region and zinc-finger and rhoGAP (rho GTPase activating protein) domains in the tail region; HUM-7 is required during embryogenesis for cytokinesis and normal cytoplasmic rearrangements, and by homology, may function in organization of the actin cytoskeleton; the precise expression and localization patterns of HUM-7 are not yet known. | Paper_evidence | WBPaper00002905 | |||||
| WBPaper00012499 | |||||||||
| WBPaper00013189 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables calmodulin binding activity and plus-end directed microfilament motor activity. Involved in actin-myosin filament sliding. Predicted to be located in actin filament. Predicted to be part of myosin complex. Expressed in accessory cell; pharynx; pm6; pm7; and terminal bulb. Human ortholog(s) of this gene implicated in celiac disease and congenital myasthenic syndrome. Is an ortholog of human MYO9A (myosin IXA). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3635 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7608) | ||||
| DOID:10608 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7609) | ||||||
| Molecular_info | Corresponding_CDS | F56A6.2a | |||||||
| F56A6.2b | |||||||||
| Corresponding_CDS_history | F56A6.2:wp224 | ||||||||
| Corresponding_transcript | F56A6.2a.1 | ||||||||
| F56A6.2b.1 | |||||||||
| Other_sequence (40) | |||||||||
| Associated_feature | WBsf663875 | ||||||||
| WBsf663876 | |||||||||
| WBsf717444 | |||||||||
| WBsf982544 | |||||||||
| WBsf982545 | |||||||||
| WBsf982546 | |||||||||
| WBsf1009104 | |||||||||
| WBsf1009105 | |||||||||
| WBsf1009106 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00048615 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00113786 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113784 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113785 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113643 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00111064 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113644 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00111056 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022381 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr13988 | ||||||||
| Expr13989 | |||||||||
| Expr1010387 | |||||||||
| Expr1031195 | |||||||||
| Expr1152384 | |||||||||
| Expr2012649 | |||||||||
| Expr2030885 | |||||||||
| Drives_construct | WBCnstr00036500 | ||||||||
| Construct_product | WBCnstr00036500 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (106) | |||||||||
| Interaction | WBInteraction000167285 | ||||||||
| WBInteraction000224119 | |||||||||
| WBInteraction000331949 | |||||||||
| WBInteraction000457597 | |||||||||
| WBInteraction000559803 | |||||||||
| WBInteraction000559804 | |||||||||
| Map_info | Map | I | Position | -18.9183 | Error | 0.037015 | |||
| Positive | Positive_clone | F56A6 | Person_evidence | WBPerson658 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 5196 | |||||||
| 5001 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00012499 | ||||||||
| WBPaper00025258 | |||||||||
| WBPaper00036376 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00043453 | |||||||||
| WBPaper00047484 | |||||||||
| WBPaper00051709 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00055566 | |||||||||
| WBPaper00064860 | |||||||||
| Remark | From Baker & Titus (1997), no precise location given. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
