WormBase Tree Display for Gene: WBGene00002078
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| WBGene00002078 | Evidence | Person_evidence | WBPerson1780 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| WBPerson2740 | |||||||||
| SMap | S_parent | Sequence | ZK742 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | xpo-1 | Person_evidence | WBPerson1780 | |||||
| Sequence_name | ZK742.1 | ||||||||
| Molecular_name | ZK742.1a | ||||||||
| ZK742.1a.1 | |||||||||
| CE23467 | |||||||||
| ZK742.1b | |||||||||
| CE31142 | |||||||||
| ZK742.1a.2 | |||||||||
| ZK742.1b.1 | |||||||||
| Other_name | imb-4 | Person_evidence | WBPerson1160 | ||||||
| CELE_ZK742.1 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | xpo-1 | ||||||||
| DB_info | Database | AceView | gene | 5I293 | |||||
| WormQTL | gene | WBGene00002078 | |||||||
| WormFlux | gene | WBGene00002078 | |||||||
| NDB | locus_tag | CELE_ZK742.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002078|UniProtKB=Q23089 | |||||||
| family | PTHR11223 | ||||||||
| NCBI | gene | 179160 | |||||||
| RefSeq | protein | NM_171484.8 | |||||||
| NM_001380696.1 | |||||||||
| TREEFAM | TREEFAM_ID | TF105695 | |||||||
| TrEMBL | UniProtAcc | Q8MPS6 | |||||||
| Q23089 | |||||||||
| UniProt_GCRP | UniProtAcc | Q23089 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 30 Jan 2008 11:39:14 | WBPerson2970 | Name_change | CGC_name | xpo-1 | ||||
| Other_name | imb-4 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | xpo | ||||||||
| Allele (123) | |||||||||
| Possibly_affected_by | WBVar02157264 | ||||||||
| Strain | WBStrain00054782 | ||||||||
| WBStrain00055455 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (46) | |||||||||
| Structured_description | Concise_description | xpo-1 encodes exportin-1, an importin-beta-like protein orthologous to Drosophila, vertebrate, and yeast exportin-1/CRM1; XPO-1 is predicted to function as a nuclear export receptor for proteins containing leucine-rich nuclear export signals; in C. elegans, XPO-1 is essential for embryogenesis and larval development, and may also be required for normal body morphology and postembryonic growth rates. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00013581 | |||||||||
| WBPaper00029236 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Apr 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable nuclear export signal receptor activity. Predicted to be involved in ribosomal large subunit export from nucleus and ribosomal small subunit export from nucleus. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and pancreatic cancer. Is an ortholog of human XPO1 (exportin 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (11) | ||||||||
| Modifies_disease | DOID:10652 | ||||||||
| Modifies_disease_in_annotation | WBDOannot00000727 | ||||||||
| Molecular_info | Corresponding_CDS | ZK742.1a | |||||||
| ZK742.1b | |||||||||
| Corresponding_transcript | ZK742.1a.1 | ||||||||
| ZK742.1a.2 | |||||||||
| ZK742.1b.1 | |||||||||
| Other_sequence (63) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (32) | ||||||||
| Expr_pattern | Expr1012777 | ||||||||
| Expr1031231 | |||||||||
| Expr1163110 | |||||||||
| Expr2018106 | |||||||||
| Expr2036244 | |||||||||
| Drives_construct | WBCnstr00037964 | ||||||||
| Construct_product | WBCnstr00037964 | ||||||||
| Regulate_expr_cluster | WBPaper00064158:xpo-1(RNAi)_downregulated | ||||||||
| WBPaper00064158:xpo-1(RNAi)_upregulated | |||||||||
| Microarray_results (38) | |||||||||
| Expression_cluster (169) | |||||||||
| Interaction (158) | |||||||||
| WBProcess | WBbiopr:00000081 | ||||||||
| Map_info | Map | V | Position | 0.910819 | Error | 0.000238 | |||
| Positive | Positive_clone | ZK742 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (26) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
