WormBase Tree Display for Gene: WBGene00002234
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| WBGene00002234 | SMap | S_parent | Sequence | M60 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | kqt-2 | Person_evidence | WBPerson655 | |||||
| Sequence_name | M60.5 | ||||||||
| Molecular_name | M60.5 | ||||||||
| M60.5.1 | |||||||||
| CE46886 | |||||||||
| Other_name | klq-2 | ||||||||
| CELE_M60.5 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | kqt-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | kqt | ||||||||
| Allele (53) | |||||||||
| Legacy_information | [Thomas JH] klq for potassium channel family, type KvLQT (human) Predicted gene M60.5 | ||||||||
| Strain | WBStrain00031596 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (21) | |||||||||
| Paralog (13) | |||||||||
| Structured_description | Concise_description | kqt-2 encodes one of three C. elegans KCNQ-like potassium channel subunits for which mutations in humans are associated with heredity diseases that affect epithelial cells, cardiac muscle and neurons; a KQT-2::GFP fusion protein is expressed exclusively in the intestine. | Paper_evidence | WBPaper00025059 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 10 May 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable calmodulin binding activity and outward rectifier potassium channel activity. Involved in defecation. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Expressed in amphid neurons; intestine; sensory neurons; tail; and in male. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Disease_relevance | The kqt genes in elegans (kqt-1, kqt-2, kqt-3) are most similar to the human KCNQ multi-gene family encoding potassium channels; mutations in human KCNQ genes have been associated with genetic disorders of cardiac arrhythmia and deafness. | Homo sapiens | Paper_evidence | WBPaper00025059 | ||||
| Accession_evidence | OMIM | 121200 | |||||||
| 121201 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 07 May 2012 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | M60.5 | |||||||
| Corresponding_CDS_history | M60.5:wp229 | ||||||||
| Corresponding_transcript | M60.5.1 | ||||||||
| Other_sequence | Oden_isotig22282 | ||||||||
| Tcol_isotig16602 | |||||||||
| Associated_feature | WBsf654202 | ||||||||
| WBsf1006087 | |||||||||
| WBsf1006088 | |||||||||
| WBsf237663 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00000528 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00051042 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017262 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051041 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3235 | ||||||||
| Expr14309 | |||||||||
| Expr14310 | |||||||||
| Expr1025992 | |||||||||
| Expr1031311 | |||||||||
| Expr1154751 | |||||||||
| Expr2012977 | |||||||||
| Expr2031209 | |||||||||
| Drives_construct | WBCnstr00011241 | ||||||||
| WBCnstr00036368 | |||||||||
| WBCnstr00040808 | |||||||||
| Construct_product | WBCnstr00011241 | ||||||||
| WBCnstr00036368 | |||||||||
| WBCnstr00040808 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (117) | |||||||||
| Interaction | WBInteraction000347547 | ||||||||
| WBInteraction000358575 | |||||||||
| Map_info | Map | X | Position | -0.274495 | Error | 0.033266 | |||
| Positive | Positive_clone | M60 | Person_evidence | WBPerson654 | |||||
| WBPerson655 | |||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4189 | |||||||
| 4468 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Also known as klq-2 | ||||||||
| Sequence connection from [Thomas JH, Wei A] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
