WormBase Tree Display for Gene: WBGene00002251
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| WBGene00002251 | SMap | S_parent | Sequence | B0457 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lat-1 | Person_evidence | WBPerson1052 | |||||
| Sequence_name | B0457.1 | ||||||||
| Molecular_name | B0457.1a | ||||||||
| B0457.1a.1 | |||||||||
| CE02945 | |||||||||
| B0457.1b | |||||||||
| CE32789 | |||||||||
| B0457.1c | |||||||||
| CE36086 | |||||||||
| B0457.1b.1 | |||||||||
| B0457.1c.1 | |||||||||
| Other_name | CELE_B0457.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | lat-1 | ||||||||
| DB_info | Database | AceView | gene | 2J197 | |||||
| WormQTL | gene | WBGene00002251 | |||||||
| WormFlux | gene | WBGene00002251 | |||||||
| NDB | locus_tag | CELE_B0457.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002251|UniProtKB=G5EDW2 | |||||||
| family | PTHR12011 | ||||||||
| NCBI | gene | 174419 | |||||||
| RefSeq | protein | NM_001381542.3 | |||||||
| NM_001393142.1 | |||||||||
| NM_001381541.2 | |||||||||
| SwissProt | UniProtAcc | G5EDW2 | |||||||
| UniProt_GCRP | UniProtAcc | G5EDW2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lat | ||||||||
| Allele (163) | |||||||||
| Strain | WBStrain00001327 | ||||||||
| WBStrain00036207 | |||||||||
| WBStrain00051140 | |||||||||
| WBStrain00055521 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (48) | |||||||||
| Paralog | WBGene00002252 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00007664 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00009304 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00014035 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00015735 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00017947 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00017948 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | lat-1 encodes a seven transmembrane domain receptor that is a member of the adhesion class of G protein-couple receptors (aGPRCs) and the nematode homolog of Latrophilin/CIRL/LPHN/CL; lat-1 is required for embryonic elongation, pharyngeal development, and sperm development and/or function; LAT-1 is expressed in developing epithelia, specifically in left epidermoblasts during dorsal intercalation, and also in pharyngeal muscles and neurons, and in the nerve ring; LAT-1 localizes to the plasma membrane; in the embryo, lat-1 expression overlaps with that of ten-1 in the dorsal left epidermoblasts; as lat-1 and ten-1 also display genetic interactions during embryonic development, the overlapping expression patterns suggest that these two genes have overlapping functions during embryogenesis. | Paper_evidence | WBPaper00041503 | |||||
| WBPaper00035406 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 22 Oct 2012 00:00:00 | ||||||||
| Automated_description | Enables endopeptidase activity. Involved in several processes, including anterior/posterior pattern specification; embryo development; and self proteolysis. Located in plasma membrane. Expressed in several structures, including ABarppaapa; AIY; Caaaaa; Caaaap; and pharynx. Is an ortholog of human ADGRL3 (adhesion G protein-coupled receptor L3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | B0457.1a | |||||||
| B0457.1b | |||||||||
| B0457.1c | |||||||||
| Corresponding_transcript | B0457.1a.1 | ||||||||
| B0457.1b.1 | |||||||||
| B0457.1c.1 | |||||||||
| Other_sequence (21) | |||||||||
| Associated_feature (40) | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern (15) | |||||||||
| Drives_construct | WBCnstr00002220 | ||||||||
| WBCnstr00004257 | |||||||||
| WBCnstr00005875 | |||||||||
| WBCnstr00011124 | |||||||||
| WBCnstr00015033 | |||||||||
| WBCnstr00015509 | |||||||||
| WBCnstr00036359 | |||||||||
| Construct_product | WBCnstr00005879 | ||||||||
| WBCnstr00005880 | |||||||||
| WBCnstr00005881 | |||||||||
| WBCnstr00005882 | |||||||||
| WBCnstr00011124 | |||||||||
| WBCnstr00036359 | |||||||||
| Antibody | WBAntibody00002038 | ||||||||
| Microarray_results (38) | |||||||||
| Expression_cluster (173) | |||||||||
| Interaction (26) | |||||||||
| Map_info | Map | II | Position | 0.926689 | Error | 0.001562 | |||
| Positive | Positive_clone | B0457 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4472 | |||||||
| 4635 | |||||||||
| 5506 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (32) | |||||||||
| Remark | Sequence connection from [Mastwal S, Yu D, Hedgecok EM], [020809 krb] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
