WormBase Tree Display for Gene: WBGene00003008
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| WBGene00003008 | SMap | S_parent | Sequence | Y54G2A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lin-22 | Person_evidence | WBPerson261 | |||||
| Sequence_name | Y54G2A.1 | ||||||||
| Molecular_name | Y54G2A.1 | ||||||||
| Y54G2A.1.1 | |||||||||
| CE26703 | |||||||||
| Other_name | hlh-9 | Person_evidence | WBPerson346 | ||||||
| 4D656 | Accession_evidence | EMBL | AF304120 | ||||||
| CELE_Y54G2A.1 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | lin-22 | ||||||||
| DB_info | Database | AceView | gene | 4D787 | |||||
| WormQTL | gene | WBGene00003008 | |||||||
| WormFlux | gene | WBGene00003008 | |||||||
| NDB | locus_tag | CELE_Y54G2A.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003008|UniProtKB=G5EF76 | |||||||
| family | PTHR10985 | ||||||||
| NCBI | gene | 177082 | |||||||
| RefSeq | protein | NM_067880.6 | |||||||
| SwissProt | UniProtAcc | G5EF76 | |||||||
| UniProt_GCRP | UniProtAcc | G5EF76 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Reference_allele | WBVar00089461 | ||||||||
| Allele (74) | |||||||||
| Legacy_information | n372 : V1-V4 divide like V5 resulting in multiple ectopic postdeirids in hermaphrodites and males and multiple ectopic rays in males. Males also have hermaphroditic Pn.p's and are mostly missing lateral alae. ES1 (hermaphrodite) ES2 (male). ME2. NA1. | ||||||||
| See also n372, n1113 | |||||||||
| Strain (12) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog | WBGene00065705 | Caenorhabditis remanei | From_analysis | OMA | |||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00076897 | Caenorhabditis remanei | From_analysis | OMA | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00026235 | Caenorhabditis briggsae | From_analysis | Hillier-set | ||||||
| OrthoMCL | |||||||||
| OMA | |||||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00220960 | Brugia malayi | From_analysis | WormBase-Compara | ||||||
| CSP26.g20760 | Caenorhabditis zanzibari | From_analysis | WormBase-Compara | ||||||
| CSP28.g2635 | Caenorhabditis panamensis | From_analysis | WormBase-Compara | ||||||
| CSP38.g6746 | Caenorhabditis quiockensis | From_analysis | WormBase-Compara | ||||||
| CSP39.g2347 | Caenorhabditis waitukubuli | From_analysis | WormBase-Compara | ||||||
| CSP39.g24520 | Caenorhabditis waitukubuli | From_analysis | WormBase-Compara | ||||||
| CSP40.g17172 | Caenorhabditis tribulationis | From_analysis | WormBase-Compara | ||||||
| Cang_2012_03_13_01775.g16729 | Caenorhabditis angaria | From_analysis | WormBase-Compara | ||||||
| Cni-lin-22 | Caenorhabditis nigoni | From_analysis | WormBase-Compara | ||||||
| Csp11.Scaffold604.g5529 | Caenorhabditis tropicalis | From_analysis | WormBase-Compara | ||||||
| Csp5_scaffold_00058.g2863 | Caenorhabditis sinica | From_analysis | WormBase-Compara | ||||||
| FL83_04786 | Caenorhabditis latens | From_analysis | WormBase-Compara | ||||||
| GCK72_014326 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||||
| Sp34_40245500 | Caenorhabditis inopinata | From_analysis | WormBase-Compara | ||||||
| chrIV_pilon.g9902 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00122648 | Caenorhabditis japonica | From_analysis | WormBase-Compara | ||||||
| WBGene00241807 | Onchocerca volvulus | From_analysis | WormBase-Compara | ||||||
| ZFIN:ZDB-GENE-980526-144 | Danio rerio | From_analysis | OrthoInspector | ||||||
| SonicParanoid | |||||||||
| ZFIN:ZDB-GENE-980526-274 | Danio rerio | From_analysis | Panther | ||||||
| PhylomeDB | |||||||||
| HGNC:5192 | Homo sapiens | From_analysis | OrthoInspector | ||||||
| SonicParanoid | |||||||||
| MGI:104853 | Mus musculus | From_analysis | Inparanoid | ||||||
| OrthoInspector | |||||||||
| SonicParanoid | |||||||||
| RGD:62081 | Rattus norvegicus | From_analysis | Inparanoid | ||||||
| OrthoInspector | |||||||||
| SonicParanoid | |||||||||
| Paralog | WBGene00001964 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00001966 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | lin-22 encodes a basic helix-loop-helix (bHLH)-containing protein that is homologous to the Drosophila hairy/Enhancer of split transcriptional repressors; during postembryonic development, lin-22 activity is required for patterning of midbody epidermal and neuronal lineages. | Paper_evidence | WBPaper00000978 | |||||
| WBPaper00002844 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 09 Aug 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in anterior/posterior pattern specification; negative regulation of gene expression; and nematode male tail tip morphogenesis. Acts upstream of or within epidermal cell fate specification. Predicted to be located in nucleus. Expressed in seam cell. Human ortholog(s) of this gene implicated in hemangiopericytoma. Is an ortholog of human HES1 (hes family bHLH transcription factor 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:264 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5192) | ||||
| Molecular_info | Corresponding_CDS | Y54G2A.1 | |||||||
| Corresponding_transcript | Y54G2A.1.1 | ||||||||
| Other_sequence | EX916391.1 | ||||||||
| Hbac_isotig05734 | |||||||||
| EG025731.1 | |||||||||
| HBC05050_1 | |||||||||
| HBC04228_1 | |||||||||
| Associated_feature | WBsf660013 | ||||||||
| WBsf718055 | |||||||||
| WBsf718056 | |||||||||
| WBsf978797 | |||||||||
| WBsf1026934 | |||||||||
| WBsf1026935 | |||||||||
| WBsf1026936 | |||||||||
| Transcription_factor | WBTranscriptionFactor000727 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00057436 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00004218 | ||||||||
| WBCnstr00036289 | |||||||||
| WBCnstr00039720 | |||||||||
| WBCnstr00039721 | |||||||||
| WBCnstr00039722 | |||||||||
| WBCnstr00039723 | |||||||||
| Construct_product | WBCnstr00016691 | ||||||||
| WBCnstr00016896 | |||||||||
| WBCnstr00036289 | |||||||||
| Regulate_expr_cluster | WBPaper00053295:lin-22(icb38)_downregulated | ||||||||
| WBPaper00053295:lin-22(icb38)_upregulated | |||||||||
| WBPaper00053295:lin-22(ot267)_downregulated | |||||||||
| WBPaper00053295:lin-22(ot267)_upregulated | |||||||||
| WBPaper00053295:lin-22(ot269)_downregulated | |||||||||
| WBPaper00053295:lin-22(ot269)_upregulated | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (67) | |||||||||
| Interaction (101) | |||||||||
| Map_info | Map | IV | Position | -6.65585 | Error | 0.044343 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | Y54G2A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Y94H6 | |||||||||
| Mapping_data | Multi_point | 683 | |||||||
| 684 | |||||||||
| 691 | |||||||||
| Reference (147) | |||||||||
| Remark | The attached sequence (Y54G2A.1) was previously connected to him-5 by mistake [030212 krb] | ||||||||
| Method | Gene |
