WormBase Tree Display for Gene: WBGene00003019
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| WBGene00003019 | SMap | S_parent | Sequence | H32C10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | lin-33 | Person_evidence | WBPerson261 | |||||
| WBPerson190 | |||||||||
| WBPerson268 | |||||||||
| Sequence_name | H32C10.2 | ||||||||
| Molecular_name | H32C10.2a | ||||||||
| H32C10.2a.1 | |||||||||
| CE21004 | |||||||||
| H32C10.2b | |||||||||
| CE49220 | |||||||||
| H32C10.2b.1 | |||||||||
| Other_name | CELE_H32C10.2 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | lin-33 | ||||||||
| DB_info | Database | AceView | gene | 4G697 | |||||
| WormQTL | gene | WBGene00003019 | |||||||
| WormFlux | gene | WBGene00003019 | |||||||
| NDB | locus_tag | CELE_H32C10.2 | |||||||
| NCBI | gene | 177361 | |||||||
| RefSeq | protein | NM_068489.5 | |||||||
| NM_001380247.1 | |||||||||
| TrEMBL | UniProtAcc | V6CIT4 | |||||||
| Q9TYQ5 | |||||||||
| UniProt_GCRP | UniProtAcc | Q9TYQ5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 05 Feb 2007 15:07:29 | WBPerson2970 | Event | Acquires_merge | WBGene00019256 | ||||
| Acquires_merge | WBGene00019256 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Allele (32) | |||||||||
| Legacy_information | n1043sd : adult hermaphrodite vulvaless (n1043 95% Egl n1043/+ 77% Egl). ES2. Male gross morphology wildtype ME3. NA2 (n1044sd (resembles n1043)). | ||||||||
| See also n1043, n1044 | |||||||||
| [C.elegansII] n1043sd : adult hermaphrodite vulvaless (n1043 95% Egl n1043/+ 77% Egl). Pn.p cells undergo cell death (ced-2,5,10 dependent). ES2. Male gross morphology wildtype ME3. OA1: n1044 (similar). Null phenotype uncertain. [Ferguson et al. 1987; Ellis et al. 1991; MT] | |||||||||
| Strain | WBStrain00026930 | ||||||||
| WBStrain00027195 | |||||||||
| WBStrain00036550 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (25) | |||||||||
| Structured_description | Concise_description | lin-33 encodes a novel protein; animals carrying a gain-of-function lin-33 mutation exhibit defects in vulval development such that some Pn.p cells that normally make up the vulva undergo inappropriate cytotoxic cell death while others adopt inappropriate cell fates; the cytotoxic cell death seen in lin-33 mutant animals is dependent upon lin-24 and a number of programmed cell death genes, including the ced-2, ced-5, and ced-12 cell corpse engulfment genes. | Paper_evidence | WBPaper00031858 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 12 Jun 2008 00:00:00 | ||||||||
| Automated_description | Enriched in several structures, including ABalaaaarl; accessory cell; excretory cell; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-7; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including procyanidin; Sirolimus; and Rifampin based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | H32C10.2a | |||||||
| H32C10.2b | |||||||||
| Corresponding_transcript | H32C10.2a.1 | ||||||||
| H32C10.2b.1 | |||||||||
| Other_sequence (14) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00033771 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00049527 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1014908 | ||||||||
| Expr1031410 | |||||||||
| Expr1153247 | |||||||||
| Expr2013176 | |||||||||
| Expr2031408 | |||||||||
| Drives_construct | WBCnstr00036282 | ||||||||
| Construct_product | WBCnstr00036282 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (165) | |||||||||
| Interaction (24) | |||||||||
| WBProcess | WBbiopr:00000013 | ||||||||
| Map_info | Map | IV | Position | 2.58 | |||||
| Positive | Positive_clone | H32C10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 1127 | |||||||
| 1128 | |||||||||
| 1129 | |||||||||
| 1130 | |||||||||
| 1131 | |||||||||
| 1132 | |||||||||
| 1511 | |||||||||
| 1512 | |||||||||
| 1792 | |||||||||
| 1793 | |||||||||
| Reference (19) | |||||||||
| Remark | [191219 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (2.5539) | ||||||||
| Method | Gene |
