WormBase Tree Display for Gene: WBGene00003087
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| WBGene00003087 | Evidence | Person_evidence | WBPerson260 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F49H12 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | lsy-2 | Person_evidence | WBPerson260 | |||||
| Sequence_name | F49H12.1 | ||||||||
| Molecular_name | F49H12.1a | ||||||||
| F49H12.1a.1 | |||||||||
| CE28437 | |||||||||
| F49H12.1b | |||||||||
| CE38521 | |||||||||
| F49H12.1b.1 | |||||||||
| Other_name | CELE_F49H12.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | lsy-2 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00003087 | |||||
| SignaLink | protein | WBGene00003087 | |||||||
| WormFlux | gene | WBGene00003087 | |||||||
| NDB | locus_tag | CELE_F49H12.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003087|UniProtKB=Q9N5S3 | |||||||
| family | PTHR24404 | ||||||||
| NCBI | gene | 180522 | |||||||
| RefSeq | protein | NM_001029525.5 | |||||||
| NM_001029526.4 | |||||||||
| SwissProt | UniProtAcc | Q9N5S3 | |||||||
| TREEFAM | TREEFAM_ID | TF315770 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N5S3 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lsy | ||||||||
| Allele (61) | |||||||||
| Strain | WBStrain00029358 | ||||||||
| WBStrain00029562 | |||||||||
| WBStrain00034790 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00095591 | ||||||||
| 00095592 | |||||||||
| 00095593 | |||||||||
| 00095594 | |||||||||
| 00095595 | |||||||||
| 00095596 | |||||||||
| 00095597 | |||||||||
| 00095598 | |||||||||
| Ortholog (16) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | lsy-2 encodes a novel C2H2 zinc-finger transcription factor that is most closely related to other nematode zinc-finger proteins; during development, lsy-2 is required for the left-right asymmetry of the ASE neurons; specifically, lsy-2 is required in ASEL for regulating the expression of the lsy-6 miRNA that controls the asymmetric expression of guanylyl cyclase chemoreceptors; a LSY-2::GFP reporter fusion is expressed ubiquitously from the 50-cell stage of embryogenesis through adulthood with expression seen in both ASEL and ASER; expression is localized to moving nuclear punctae. | Paper_evidence | WBPaper00027031 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 16 May 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable metal ion binding activity. Involved in nematode larval development; neuron fate specification; and positive regulation of gene expression. Located in nucleus. Expressed in several structures, including ASE; head muscle; head neurons; intestine; and somatic nervous system. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F49H12.1a | |||||||
| F49H12.1b | |||||||||
| Corresponding_CDS_history | F49H12.1:wp142 | ||||||||
| Corresponding_transcript | F49H12.1a.1 | ||||||||
| F49H12.1b.1 | |||||||||
| Other_sequence (25) | |||||||||
| Associated_feature (15) | |||||||||
| Gene_product_binds (376) | |||||||||
| Transcription_factor | WBTranscriptionFactor000186 | ||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Expr3799 | ||||||||
| Expr7577 | |||||||||
| Expr13098 | |||||||||
| Expr1020695 | |||||||||
| Expr1031462 | |||||||||
| Expr1151716 | |||||||||
| Expr1200126 | |||||||||
| Expr1200360 | |||||||||
| Expr2013305 | |||||||||
| Expr2031536 | |||||||||
| Drives_construct (12) | |||||||||
| Construct_product | WBCnstr00016729 | ||||||||
| WBCnstr00016772 | |||||||||
| WBCnstr00018899 | |||||||||
| WBCnstr00036240 | |||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (119) | |||||||||
| Interaction (99) | |||||||||
| Map_info | Map | X | Position | -17.0549 | Error | 0.011911 | |||
| Positive | Positive_clone | F49H12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4371 | |||||||
| 5027 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
