WormBase Tree Display for Gene: WBGene00003289
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| WBGene00003289 | Evidence | Paper_evidence | WBPaper00004928 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F55A11 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | mir-61 | Person_evidence | WBPerson18 | |||||
| Sequence_name | F55A11.9 | ||||||||
| Molecular_name | F55A11.9 | ||||||||
| F55A11.9a | |||||||||
| F55A11.9b | |||||||||
| Other_name | cel-mir-61 | Remark | miRBase V21 import | ||||||
| Cel-Mir-279-o9 | Remark | MirGeneDB 2.1 import | |||||||
| CELE_F55A11.9 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | mir-61 | ||||||||
| DB_info | Database | miRBase | acc | MI0000032 | |||||
| SignaLink | mirna | cel-mir-61 | |||||||
| MirGeneDB | cel | Cel-Mir-279-o9 | |||||||
| NDB | locus_tag | CELE_F55A11.9 | |||||||
| NCBI | gene | 260114 | |||||||
| RefSeq | protein | NR_000792.2 | |||||||
| RNAcentral | URSid | URS00000CFCFA | |||||||
| URS000020AD85 | |||||||||
| URS0000760C75 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001265 | |||||||
| Gene_class | mir | ||||||||
| Allele (11) | |||||||||
| Strain | WBStrain00005026 | ||||||||
| WBStrain00047228 | |||||||||
| WBStrain00047235 | |||||||||
| WBStrain00047229 | |||||||||
| WBStrain00047233 | |||||||||
| WBStrain00047234 | |||||||||
| WBStrain00054694 | |||||||||
| In_cluster | MIR-279 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00106241 | ||||||||
| 00106242 | |||||||||
| Structured_description | Concise_description | mir-61 encodes a microRNA, a small non-protein coding RNA with a predicted ortholog in C. briggsae; during postembryonic development, mir-61 functions in a feedback loop that promotes the secondary vulval cell fate; in regulating the secondary fate, mir-61 lies downstream of LIN-12/Notch signaling and upstream of vav-1, which encodes a protooncogene that negatively regulates LIN-12 activity and whose expression is, in turn, negatively regulated by mir-61; Northern analyses indicate that mir-61 is expressed constitutively throughout development in normal worms and in glp-4(bn2) adults, while a mir-61::gfp promoter fusion indicates that mir-61 is expressed in the P5.p and P7.p vulval precursor cells and their descendants as well as in the gonad; mir-61 expression is dependent upon LAG-1 binding sites in its promoter region. | Paper_evidence | WBPaper00004927 | |||||
| WBPaper00005825 | |||||||||
| WBPaper00026909 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 20 Feb 2009 00:00:00 | ||||||||
| Automated_description | Involved in miRNA-mediated post-transcriptional gene silencing and regulation of vulval development. Expressed in several structures, including P5.p hermaphrodite; P5.pa; P5.pp; P7.p hermaphrodite; and P7.pa. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_transcript | F55A11.9 | |||||||
| F55A11.9a | |||||||||
| F55A11.9b | |||||||||
| Other_sequence | AJ487585 | ||||||||
| Associated_feature | WBsf1001437 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00112526 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00112527 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2489 | ||||||||
| Expr8464 | |||||||||
| Expr8597 | |||||||||
| Expr8598 | |||||||||
| Expr10364 | |||||||||
| Expr10893 | |||||||||
| Drives_construct | WBCnstr00000070 | ||||||||
| WBCnstr00005507 | |||||||||
| WBCnstr00013390 | |||||||||
| WBCnstr00013391 | |||||||||
| WBCnstr00015279 | |||||||||
| WBCnstr00016902 | |||||||||
| Expression_cluster (23) | |||||||||
| Interaction | WBInteraction000005760 | ||||||||
| WBInteraction000542491 | |||||||||
| Map_info | Positive | Inside_rearr | nDf59 | ||||||
| Positive_clone | F55A11 | Inferred_automatically | From CDS info | ||||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Pos_neg_data | 10930 | |||||||
| Interpolated_map_position | V | 3.34488 | |||||||
| Reference (21) | |||||||||
| Method | Gene |
