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WormBase Tree Display for Gene: WBGene00003351

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Name Class

WBGene00003351EvidencePaper_evidenceWBPaper00005879
SMapS_parentSequenceY102A5D
IdentityVersion1
NameCGC_namemir-257Person_evidenceWBPerson18
Sequence_nameY102A5D.4
Molecular_nameY102A5D.4
Y102A5D.4a
Other_namecel-mir-257RemarkmiRBase V21 import
CELE_Y102A5D.4Accession_evidenceNDBBX284605
Public_namemir-257
DB_infoDatabasemiRBaseaccMI0000334
NDBlocus_tagCELE_Y102A5D.4
NCBIgene3565172
RefSeqproteinNR_002405.2
RNAcentralURSidURS00002B7096
URS000034D37E
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001265
Gene_classmir
Allele (31)
StrainWBStrain00027478
RNASeq_FPKM (74)
Structured_descriptionConcise_descriptionmir-257 encodes a microRNA, a small non-protein coding RNA; mir-257 is uniformly expressed from the embryonic stage to the adult stage; many of the known microRNAs are involved in post-transcriptional regulation of genes; the precise function of miR-257 is unknown.Paper_evidenceWBPaper00005879
Curator_confirmedWBPerson324
Date_last_updated25 Feb 2005 00:00:00
Automated_descriptionIs affected by several genes including alg-1; alg-2; and meg-3 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_transcriptY102A5D.4
Y102A5D.4a
Associated_featureWBsf979129
Experimental_infoExpr_patternExpr8434
Expr10965
Drives_constructWBCnstr00013301
Expression_clusterWBPaper00048474:SpaceRadiation-Microgravity_upregulated_N2
WBPaper00049006:nicotine_upregulated_F1
WBPaper00051404:alg-1(gk214)_upregulated_miRNA
WBPaper00051404:alg-2(ok304)_downregulated_miRNA
WBPaper00051404:alg-5(ram2)_downregulated_miRNA
WBPaper00051404:alg-5(tm1163)_downregulated_miRNA
WBPaper00057162:meg-3_meg-4_downregulated_sRNA
Map_infoMapVPosition12.8033Error0.001776
PositivePositive_cloneY102A5DInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005879
WBPaper00031335
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
The annotation of cel-mir-257 as a microRNA was questioned by Jan et al (Nature 2011 469:97-101). The pattern of reads from deep sequencing datasets aggregated in miRBase and mapping to the locus is not consistent with microRNA processing. The sequence is removed from miRBase 21.
MethodGene