WormBase Tree Display for Gene: WBGene00003375

WBGene00003375 Evidence: Person_evidence: WBPerson415
  SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 1
    Name: CGC_name: mlp-1 Person_evidence: WBPerson910
      Sequence_name: T04C9.4
      Molecular_name (15)
      Other_name: CELE_T04C9.4 Accession_evidence: NDB BX284603
      Public_name: mlp-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:31 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mlp
    Allele (55)
    Strain: WBStrain00001691
      WBStrain00002272
      WBStrain00031656
    RNASeq_FPKM (74)
    GO_annotation: 00022583
      00022584
      00022585
      00022586
    Ortholog (48)
    Paralog: WBGene00015216 Caenorhabditis elegans From_analysis: Panther
      WBGene00017644 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: mlp-1 encodes a LIM domain-containing protein that is a member of the MLP/CRP family of muscle LIM domain proteins. Paper_evidence: WBPaper00024208
          Curator_confirmed: WBPerson1843
          Date_last_updated: 19 Jun 2007 00:00:00
      Automated_description: Predicted to enable metal ion binding activity. Located in striated muscle dense body. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1M and hypertrophic cardiomyopathy 12. Is an ortholog of human CSRP1 (cysteine and glycine rich protein 1); CSRP2 (cysteine and glycine rich protein 2); and CSRP3 (cysteine and glycine rich protein 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:11984 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2472)
      DOID:0110449 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2472)
      DOID:12930 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2472)
      DOID:0110318 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2472)
  Molecular_info: Corresponding_CDS: T04C9.4a
      T04C9.4b
      T04C9.4c
      T04C9.4d
    Corresponding_CDS_history: T04C9.4:wp33
      T04C9.4a:wp82
      T04C9.4b:wp82
      T04C9.4c:wp82
      T04C9.4c:wp236
      T04C9.4c:wp275
    Corresponding_transcript: T04C9.4a.1
      T04C9.4a.2
      T04C9.4a.3
      T04C9.4b.1
      T04C9.4c.1
      T04C9.4c.2
      T04C9.4d.1
    Other_sequence: Dviv_isotig15483
      Tcir_isotig05194
      XI00161
      ZP00014
      AI317905.1
      HBC18560_1
      MI00042
      Hbac_isotig05874
      LSC00926_1
      ZPC00126_1
      JK315084.1
      FG349314.1
      BM277450.1
      AA620282.1
      FG350180.1
      OOC03038_1
      AI363512.1
      HBC03977_1
      TSC00482_1
      MI00716
      CK855008.1
      RS07496
      GRC00824_1
      NBC04840_1
      H39471.1
      Dviv_isotig15484
      HG03060
      TS02016
      XI01242
      GRC00280_1
      CK850497.1
      JI210901.1
      MHC12053_1
      CB043668.1
      RSC00233_1
      GO249860.1
      BXC03474_1
      NB07011
      JI467787.1
      EX914537.1
      FG583273.1
      AI130313.1
      AW506031.1
      Tcir_isotig05193
      XI00094
      Tcol_isotig08060
      MIC00477_1
      OCC00020_1
      ACC02657_1
      Name_isotig04338
      GPC01926_1
      ACC02388_1
      Tcir_isotig20006
      JI212302.1
      FG349110.1
      Acan_isotig00842
      XI03753
      MIC00797_1
      XIC00946_1
      DN557944.1
      MI03576
      EX009493.1
      EX501186.1
      ACC02192_1
      ZPC00158_1
      Oden_isotig12686
      ES564128.1
      XIC01088_1
      MHC05705_1
      RSC02941_1
      ES565665.1
      XIC00120_1
      Oden_isotig12687
      HGC00717_1
      Acan_isotig00843
      MH02423
      OVC00667_1
      AW453452.1
      MHC08257_1
      XI00617
      HBC02008_1
      FG587059.1
      Tcol_isotig08061
      ES565555.1
      TDC00112_1
      AI130314.1
      PPC03434_1
      OVC03929
      ACC04022_1
      ES564912.1
      MI03750
      XI01070
      FG583759.1
      ES742787.1
      GPC00562_1
      Acan_isotig00844
      WBC02331_1
      AI124457.1
      AI111217.1
      XI00823
      HC05408
      AW600228.1
      MI00041
      GO249445.1
      AI055778.1
      FG350372.1
      EX008032.1
      XI01807
      XIC00019_1
      EX010951.1
      XI00008
      JI174918.1
      WBC01883_1
      CB013280.1
      GE639075.1
      EX910839.1
      FG347813.1
      TMC00486_1
      BMC00173_1
      CJC11109_1
      FG354531.1
      EX501307.1
      BG577628.1
      CBC06256_1
      TSC12132_1
      GP01106
      Tcir_isotig23745
      HCC06975_1
      AA917231.1
      EX500977.1
    Associated_feature: WBsf666463
      WBsf666943
      WBsf666944
      WBsf717910
      WBsf717911
      WBsf992591
      WBsf226745
  Experimental_info: RNAi_result (13)
    Expr_pattern (11)
    Drives_construct: WBCnstr00002515
      WBCnstr00002663
      WBCnstr00004365
      WBCnstr00004366
      WBCnstr00036152
    Construct_product: WBCnstr00013958
      WBCnstr00036152
    Microarray_results (40)
    Expression_cluster (237)
    Interaction (20)
  Map_info: Map: III Position: -1.42778 Error: 0.000247
    Positive: Positive_clone: T04C9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4546
        4769
    Pseudo_map_position
  Reference: WBPaper00024208
    WBPaper00038444
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene