WormBase Tree Display for Gene: WBGene00003402
expand all nodes | collapse all nodes | view schema
| WBGene00003402 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mpk-2 | Person_evidence | WBPerson1160 | |||||
| Sequence_name | C04G6.1 | ||||||||
| Molecular_name | C04G6.1a | ||||||||
| C04G6.1a.1 | |||||||||
| CE31290 | |||||||||
| C04G6.1b | |||||||||
| CE32111 | |||||||||
| C04G6.1c | |||||||||
| CE36972 | |||||||||
| C04G6.1b.1 | |||||||||
| C04G6.1c.1 | |||||||||
| C04G6.1c.2 | |||||||||
| Other_name | CELE_C04G6.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | mpk-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mpk | ||||||||
| Allele (62) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes predicted MAP kinase. [Lackner et al. 1994; SD] | ||||||||
| Strain | WBStrain00031366 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (36) | |||||||||
| Paralog (21) | |||||||||
| Structured_description | Concise_description | mpk-2 encodes a mitogen activated protein (MAP) kinase; by homology, MPK-2 is predicted to function as a serine/threonine kinase that acts downstream of a receptor tyrosine kinase in a cell signaling pathway; however, as loss of mpk-2 activity via large-scale RNAi screens does not produce any obvious abnormalities, the precise role of MPK-2 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00001870 | |||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Is an ortholog of human MAPK7 (mitogen-activated protein kinase 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6880) | ||||
| Molecular_info | Corresponding_CDS | C04G6.1a | |||||||
| C04G6.1b | |||||||||
| C04G6.1c | |||||||||
| Corresponding_CDS_history | C04G6.1:wp81 | ||||||||
| Corresponding_transcript | C04G6.1a.1 | ||||||||
| C04G6.1b.1 | |||||||||
| C04G6.1c.1 | |||||||||
| C04G6.1c.2 | |||||||||
| Other_sequence (13) | |||||||||
| Associated_feature | WBsf644161 | ||||||||
| WBsf987801 | |||||||||
| WBsf1012186 | |||||||||
| WBsf221229 | |||||||||
| WBsf221230 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00112956 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00087945 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076078 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113154 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113186 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028462 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00039667 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010153 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113100 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr14466 | ||||||||
| Expr1025301 | |||||||||
| Expr1031572 | |||||||||
| Expr1143759 | |||||||||
| Expr2013668 | |||||||||
| Expr2031902 | |||||||||
| Drives_construct | WBCnstr00036136 | ||||||||
| Construct_product | WBCnstr00036136 | ||||||||
| Regulate_expr_cluster | WBPaper00056586:kri-1(ok1251);mpk-2(ok219)_downregulated | ||||||||
| WBPaper00056586:kri-1(ok1251);mpk-2(ok219)_upregulated | |||||||||
| WBPaper00056586:mpk-2(ok219)_downregulated | |||||||||
| WBPaper00056586:mpk-2(ok219)_upregulated | |||||||||
| Microarray_results (35) | |||||||||
| Expression_cluster (190) | |||||||||
| Interaction (42) | |||||||||
| Map_info | Map | II | Position | -2.12701 | Error | 0.112736 | |||
| Positive | Positive_clone | C04G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| SD#10 | |||||||||
| Mapping_data | Multi_point | 4345 | |||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
