WormBase Tree Display for Gene: WBGene00003504
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WBGene00003504 | Evidence | CGC_data_submission | |||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | ZK1098 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | mut | ||||||
Allele (46) | |||||||
Strain | WBStrain00003332 | ||||||
WBStrain00028942 | |||||||
WBStrain00028975 | |||||||
WBStrain00034635 | |||||||
WBStrain00040468 | |||||||
In_cluster | conserved_miRNA_siRNA_cluster | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (24) | |||||||
Ortholog (28) | |||||||
Paralog | WBGene00014220 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00013256 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
WBGene00012290 | Caenorhabditis elegans | From_analysis | Panther | ||||
Structured_description | Concise_description | mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference. | Paper_evidence | WBPaper00003711 | |||
WBPaper00003722 | |||||||
WBPaper00003956 | |||||||
WBPaper00004198 | |||||||
WBPaper00005077 | |||||||
WBPaper00024699 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 28 Dec 2005 00:00:00 | ||||||
Automated_description | Predicted to enable 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing. Involved in obsolete negative regulation of transposition, DNA-mediated; olfactory learning; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytosol; mutator focus; and nucleus. Expressed in AWCL; AWCR; and somatic cell. Is an ortholog of human EXD3 (exonuclease 3'-5' domain containing 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | ZK1098.8 | |||||
Corresponding_transcript | ZK1098.8.1 | ||||||
Other_sequence | CR03715 | ||||||
CBC14770_1 | |||||||
CRC08288_1 | |||||||
Associated_feature | WBsf667292 | ||||||
WBsf667293 | |||||||
WBsf227313 | |||||||
Experimental_info | RNAi_result (12) | ||||||
Expr_pattern (11) | |||||||
Drives_construct | WBCnstr00003803 | ||||||
WBCnstr00014695 | |||||||
WBCnstr00014696 | |||||||
WBCnstr00018512 | |||||||
WBCnstr00036084 | |||||||
Construct_product | WBCnstr00014695 | ||||||
WBCnstr00014696 | |||||||
WBCnstr00018512 | |||||||
WBCnstr00036084 | |||||||
Antibody | WBAntibody00000828 | ||||||
Microarray_results (20) | |||||||
Expression_cluster (133) | |||||||
Interaction (31) | |||||||
WBProcess | WBbiopr:00000057 | ||||||
Map_info | Map | III | Position | 0.579676 | Error | 0.00167 | |
Positive | Positive_clone | ZK1098 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4504 | |||||
4993 | |||||||
Pseudo_map_position | |||||||
Reference (129) | |||||||
Remark | Sequence connection from [Ketting RF] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |