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WormBase Tree Display for Gene: WBGene00003589

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Name Class

WBGene00003589SMapS_parentSequenceT07C4
IdentityVersion1
NameCGC_namenex-2
Sequence_nameT07C4.9
Molecular_nameT07C4.9a
T07C4.9a.1
CE23956
T07C4.9b
CE35364
T07C4.9b.1
Other_nameCELE_T07C4.9Accession_evidenceNDBBX284603
Public_namenex-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnex
Allele (81)
Legacy_information[C.elegansII] NMK. Encodes predicted protein with annexin similarity. [CGC]
StrainWBStrain00031613
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (42)
ParalogWBGene00003588Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003591Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00003590Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionnex-2 encodes an annexin, a member of a family of calcium-dependent phospholipid binding proteins; by homology, NEX-2 could function in a number of processes, such as membrane fusion, cytoskeletal interactions, and intracellular signaling; however, as loss of nex-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of NEX-2 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00004651
WBPaper00005654
WBPaper00005874
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables phospholipid binding activity and sulfur compound binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); and reproductive organ cancer (multiple). Is an ortholog of human ANXA7 (annexin A7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDST07C4.9a
T07C4.9b
Corresponding_transcriptT07C4.9a.1
T07C4.9b.1
Other_sequence (229)
Associated_feature (13)
Experimental_infoRNAi_resultWBRNAi00052733Inferred_automaticallyRNAi_primary
WBRNAi00022441Inferred_automaticallyRNAi_primary
WBRNAi00080499Inferred_automaticallyRNAi_primary
WBRNAi00114645Inferred_automaticallyRNAi_primary
WBRNAi00035295Inferred_automaticallyRNAi_primary
WBRNAi00087554Inferred_automaticallyRNAi_primary
WBRNAi00007400Inferred_automaticallyRNAi_primary
Expr_patternChronogram1545
Chronogram1631
Expr6628
Expr8285
Expr1013118
Expr1031639
Expr1156342
Expr2013980
Expr2032220
Drives_constructWBCnstr00002403
WBCnstr00036021
Construct_productWBCnstr00036021
AntibodyWBAntibody00001199
Microarray_results (29)
Expression_cluster (223)
Interaction (11)
Map_infoMapIIIPosition2.32098Error0.002448
PositivePositive_cloneT07C4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5079
Pseudo_map_position
Reference (13)
RemarkIII 2.4
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene