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WormBase Tree Display for Gene: WBGene00003628

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Name Class

WBGene00003628EvidencePaper_evidenceWBPaper00003416
SMapS_parentSequenceC07A12
IdentityVersion1
NameCGC_namenhr-35Person_evidenceWBPerson600
Sequence_nameC07A12.3
Molecular_nameC07A12.3a
C07A12.3a.1
CE30855
C07A12.3b
CE38483
C07A12.3b.1
Other_nameCELE_C07A12.3Accession_evidenceNDBBX284606
Public_namenhr-35
DB_infoDatabaseWormQTLgeneWBGene00003628
WormFluxgeneWBGene00003628
NDBlocus_tagCELE_C07A12.3
PanthergeneCAEEL|WormBase=WBGene00003628|UniProtKB=Q17771
familyPTHR24083
NCBIgene180725
RefSeqproteinNM_001392764.1
NM_001029194.4
SwissProtUniProtAccQ17771
UniProt_GCRPUniProtAccQ17771
OMIMgene600281
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnhr
Allele (71)
StrainWBStrain00051990
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (35)
Paralog (42)
Structured_descriptionAutomated_descriptionPredicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including Fanconi renotubular syndrome 4; glucose metabolism disease (multiple); and liver disease (multiple). Is an ortholog of human HNF4A (hepatocyte nuclear factor 4 alpha).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111099Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
DOID:13809Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
DOID:9993Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
DOID:1686Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
DOID:5082Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
DOID:0080760Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5024)
Molecular_infoCorresponding_CDSC07A12.3a
C07A12.3b
Corresponding_CDS_historyC07A12.3:wp142
Corresponding_transcriptC07A12.3a.1
C07A12.3b.1
Other_sequence (33)
Associated_featureWBsf648020
WBsf648021
WBsf978561
WBsf1004981
WBsf1004982
WBsf1004983
WBsf235591
WBsf235592
WBsf235593
Transcription_factorWBTranscriptionFactor000618
Experimental_infoRNAi_resultWBRNAi00114327Inferred_automaticallyRNAi_primary
WBRNAi00028612Inferred_automaticallyRNAi_primary
WBRNAi00086264Inferred_automaticallyRNAi_primary
WBRNAi00010357Inferred_automaticallyRNAi_primary
WBRNAi00000562Inferred_automaticallyRNAi_primary
WBRNAi00039962Inferred_automaticallyRNAi_primary
Expr_patternExpr3943
Expr7418
Expr1024855
Expr1031674
Expr1144041
Expr2014183
Expr2032424
Drives_constructWBCnstr00011767
WBCnstr00012561
WBCnstr00035987
Construct_productWBCnstr00016582
WBCnstr00035987
Microarray_results (23)
Expression_cluster (124)
InteractionWBInteraction000030189
WBInteraction000031367
WBInteraction000227620
WBInteraction000235412
WBInteraction000505305
WBInteraction000505327
WBInteraction000534590
Map_infoMapXPosition-7.34557Error0.011059
PositivePositive_cloneC07A12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4395
Pseudo_map_position
ReferenceWBPaper00026592
WBPaper00027309
WBPaper00038491
WBPaper00055090
WBPaper00061738
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene