WormBase Tree Display for Gene: WBGene00003791

WBGene00003791 SMap: S_parent: Sequence: F07A11
  Identity: Version: 2
    Name: CGC_name: npp-5 Person_evidence: WBPerson1780
      Sequence_name: F07A11.3
      Molecular_name: F07A11.3
        F07A11.3.1
        CE03145
      Other_name: Nup107 Paper_evidence: WBPaper00026834
        CELE_F07A11.3 Accession_evidence: NDB BX284602
      Public_name: npp-5
    DB_info: Database: AceView gene 2L888
        WormQTL gene WBGene00003791
        WormFlux gene WBGene00003791
        NDB locus_tag CELE_F07A11.3
        Panther gene CAEEL|WormBase=WBGene00003791|UniProtKB=Q19131
          family PTHR13003
        NCBI gene 174779
        RefSeq protein NM_064080.6
        SwissProt UniProtAcc Q19131
        UniProt_GCRP UniProtAcc Q19131
        OMIM gene 607617
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 15 Mar 2007 08:57:28 WBPerson2970 Name_change: Other_name: Nup107
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: npp
    Allele (69)
    Strain: WBStrain00036637
      WBStrain00003837
      WBStrain00003840
      WBStrain00003841
    RNASeq_FPKM (74)
    GO_annotation (37)
    Contained_in_operon: CEOP2718
    Ortholog (31)
    Structured_description: Automated_description: Predicted to be a structural constituent of nuclear pore. Involved in several processes, including kinetochore assembly; protein localization to kinetochore; and regulation of nucleus size. Located in nuclear membrane. Part of nuclear pore. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome; nephrotic syndrome type 11; and ovarian dysgenesis 6. Is an ortholog of human NUP107 (nucleoporin 107). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080694 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29914)
      DOID:0080498 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29914)
      DOID:0080385 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29914)
  Molecular_info: Corresponding_CDS: F07A11.3
    Corresponding_transcript: F07A11.3.1
    Other_sequence: CBC07538_1
      CR03653
      CRC05182_1
      CR04595
      CR03960
      CRC05640_1
    Associated_feature: WBsf650602
      WBsf666172
      WBsf223966
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr1027606
      Expr1031777
      Expr1147819
      Expr2014390
      Expr2032631
    Drives_construct: WBCnstr00035865
    Construct_product: WBCnstr00005566
      WBCnstr00014542
      WBCnstr00035865
    Antibody: WBAntibody00001891
      WBAntibody00002304
    Microarray_results (20)
    Expression_cluster: WBPaper00028451:Low_abundance_spermatogenesis_enriched
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00042477:prp-8(RNAi)_upregulated_RNAseq
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053615:SMO-1_target
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_protein
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:FLP
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:kle-2_4298-vrk-1
      WBPaper00061527:R07E4.5-skp-1_1608
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025032:cluster_13
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_B
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040876:mir-35_upregulated
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(23_min)
      [cgc5767]:expression_class_E_pi(23_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:Cluster_F
      [cgc6390]:intrinsic
    Interaction (164)
  Map_info: Map: II Position: 3.78634 Error: 0.003937
    Positive: Positive_clone: F07A11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00006202
    WBPaper00026834
    WBPaper00032497
    WBPaper00036964
    WBPaper00040620
    WBPaper00040897
    WBPaper00061547
    WBPaper00063941
    WBPaper00064641
    WBPaper00065742
  Remark: Sequence connection from [Askjaer P, Mattaj IW]. krb 13/11/01
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene