WormBase Tree Display for Gene: WBGene00003842
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| WBGene00003842 | Evidence | Accession_evidence | EMBL | AF110415 | |||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CHROMOSOME_I | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | oct-1 | |||||||
| Sequence_name | F52F12.1 | ||||||||
| Molecular_name | F52F12.1a | ||||||||
| F52F12.1a.1 | |||||||||
| CE41244 | |||||||||
| F52F12.1b | |||||||||
| CE29329 | |||||||||
| F52F12.1b.1 | |||||||||
| Other_name | CELE_F52F12.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | oct-1 | ||||||||
| DB_info | Database | AceView | gene | 1K466 | |||||
| WormQTL | gene | WBGene00003842 | |||||||
| WormFlux | gene | WBGene00003842 | |||||||
| NDB | locus_tag | CELE_F52F12.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003842|UniProtKB=Q9U539 | |||||||
| family | PTHR24064 | ||||||||
| NCBI | gene | 172841 | |||||||
| RefSeq | protein | NM_060216.6 | |||||||
| NM_001026311.7 | |||||||||
| SwissProt | UniProtAcc | Q9U539 | |||||||
| UniProt_GCRP | UniProtAcc | Q9U539 | |||||||
| OMIM | gene | 603377 | |||||||
| 604190 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | oct | ||||||||
| Allele (52) | |||||||||
| Strain | WBStrain00031788 | ||||||||
| WBStrain00033137 | |||||||||
| WBStrain00036072 | |||||||||
| WBStrain00036096 | |||||||||
| WBStrain00037469 | |||||||||
| WBStrain00033403 | |||||||||
| WBStrain00033406 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00100464 | ||||||||
| 00100465 | |||||||||
| 00100466 | |||||||||
| 00100467 | |||||||||
| 00100468 | |||||||||
| 00100469 | |||||||||
| 00100470 | |||||||||
| 00111898 | |||||||||
| 00111899 | |||||||||
| 00111900 | |||||||||
| Ortholog (65) | |||||||||
| Paralog (28) | |||||||||
| Structured_description | Concise_description | oct-1 encodes a organic cation transporter predicted to contain twelve transmembrane domains; OCT-1 induces the transport of the prototypical organic cation tetraethylammonium when expressed in mammalian cells, and has broad substrate specificity; OCT-1 is orthologous to human OCTN2 (OMIM:603377, mutated in primary carnitine deficiency). | Paper_evidence | WBPaper00003511 | |||||
| WBPaper00004103 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables organic cation transmembrane transporter activity. Involved in determination of adult lifespan and organic cation transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including myelodysplastic syndrome; rheumatoid arthritis; and systemic primary carnitine deficiency disease. Is an ortholog of human SLC22A4 (solute carrier family 22 member 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:7148 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10968) | ||||
| DOID:0050908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10969) | ||||||
| DOID:8778 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10969) | ||||||
| DOID:14365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10969) | ||||||
| DOID:0050700 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10969) | ||||||
| DOID:655 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10969) | ||||||
| DOID:3021 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10966) | ||||||
| Molecular_info | Corresponding_CDS | F52F12.1a | |||||||
| F52F12.1b | |||||||||
| Corresponding_CDS_history | F52F12.1a:wp177 | ||||||||
| Corresponding_transcript | F52F12.1a.1 | ||||||||
| F52F12.1b.1 | |||||||||
| Other_sequence | AF110415 | ||||||||
| JI476195.1 | |||||||||
| ACC03891_1 | |||||||||
| JI461435.1 | |||||||||
| Associated_feature | WBsf220157 | ||||||||
| WBsf220158 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00048007 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00003739 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram590 | ||||||||
| Expr6140 | |||||||||
| Expr1023926 | |||||||||
| Expr1151822 | |||||||||
| Expr2014601 | |||||||||
| Expr2032834 | |||||||||
| Drives_construct | WBCnstr00002824 | ||||||||
| WBCnstr00035838 | |||||||||
| Construct_product | WBCnstr00035838 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (91) | |||||||||
| Interaction (13) | |||||||||
| Map_info | Map | I | Position | 3.98287 | Error | 0.001114 | |||
| Positive | Positive_clone | F52F12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4447 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003511 | ||||||||
| WBPaper00029012 | |||||||||
| WBPaper00030372 | |||||||||
| WBPaper00038487 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00044259 | |||||||||
| WBPaper00047078 | |||||||||
| WBPaper00050377 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
