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WormBase Tree Display for Gene: WBGene00004028

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Name Class

WBGene00004028EvidenceAccession_evidenceEMBLAB015041
SMapS_parentSequenceY18H1A
IdentityVersion1
NameCGC_namepif-1Person_evidenceWBPerson334
Sequence_nameY18H1A.6
Molecular_name (12)
Other_namecePIF1Accession_evidenceEMBLAB015041
CELE_Y18H1A.6Accession_evidenceNDBBX284601
Public_namepif-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpif
Allele (175)
StrainWBStrain00003036
RNASeq_FPKM (74)
GO_annotation (29)
Ortholog (36)
Structured_descriptionConcise_descriptionpif-1 encodes a DNA-dependent ATPase and 5'-3' DNA helicase orthologous to Saccharomyces Pif1p and vertebrate PIF1; by homology, PIF-1 is predicted to function in maintenance of both mitochondrial and nuclear genome integrity; PIF-1 is also predicted to function as a negative regulator of telomerase activity that acts by displacing telomerase from the ends of DNA; loss of pif-1 activity via RNAi results in induction of the mitochondrial unfolded protein response.Paper_evidenceWBPaper00028575
WBPaper00031057
WBPaper00024269
Curator_confirmedWBPerson1843
Date_last_updated10 Apr 2014 00:00:00
Automated_descriptionPredicted to enable 5'-3' DNA helicase activity. Predicted to be involved in DNA duplex unwinding and DNA replication. Predicted to be located in replication fork. Is an ortholog of human PIF1 (PIF1 5'-to-3' DNA helicase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY18H1A.6a
Y18H1A.6b
Y18H1A.6c
Y18H1A.6d
Corresponding_transcriptY18H1A.6a.1
Y18H1A.6b.1
Y18H1A.6c.1
Y18H1A.6d.1
Other_sequence (25)
Associated_featureWBsf643027
WBsf655866
WBsf982562
WBsf217156
Experimental_infoRNAi_resultWBRNAi00055630Inferred_automaticallyRNAi_primary
WBRNAi00116555Inferred_automaticallyRNAi_primary
WBRNAi00004551Inferred_automaticallyRNAi_primary
WBRNAi00084348Inferred_automaticallyRNAi_primary
WBRNAi00028232Inferred_automaticallyRNAi_primary
WBRNAi00004550Inferred_automaticallyRNAi_primary
WBRNAi00004552Inferred_automaticallyRNAi_primary
WBRNAi00075580Inferred_automaticallyRNAi_primary
WBRNAi00062421Inferred_automaticallyRNAi_primary
WBRNAi00055629Inferred_automaticallyRNAi_primary
Expr_patternChronogram1274
Expr6905
Expr1012832
Expr1031930
Expr1159144
Expr2014920
Expr2033155
Drives_constructWBCnstr00003536
Microarray_results (27)
Expression_cluster (156)
Interaction (52)
Map_infoMapIPosition-18.5478Error0.046141
PositivePositive_cloneY18H1AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00024269
WBPaper00038491
WBPaper00055090
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene