WormBase Tree Display for Gene: WBGene00004030
expand all nodes | collapse all nodes | view schema
| WBGene00004030 | Evidence | Paper_evidence | WBPaper00003361 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F07C6 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | pin-2 | Person_evidence | WBPerson260 | |||||
| Sequence_name | F07C6.1 | ||||||||
| Molecular_name | F07C6.1a | ||||||||
| F07C6.1a.1 | |||||||||
| CE47311 | |||||||||
| F07C6.1b | |||||||||
| CE47192 | |||||||||
| F07C6.1b.1 | |||||||||
| Other_name | CELE_F07C6.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | pin-2 | ||||||||
| DB_info | Database | AceView | gene | 4N561 | |||||
| WormQTL | gene | WBGene00004030 | |||||||
| WormFlux | gene | WBGene00004030 | |||||||
| NDB | locus_tag | CELE_F07C6.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004030|UniProtKB=Q19157 | |||||||
| family | PTHR24210 | ||||||||
| NCBI | gene | 178234 | |||||||
| RefSeq | protein | NM_001268744.3 | |||||||
| NM_001268743.3 | |||||||||
| SwissProt | UniProtAcc | Q19157 | |||||||
| UniProt_GCRP | UniProtAcc | Q19157 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pin | ||||||||
| Allele (37) | |||||||||
| Strain | WBStrain00036182 | ||||||||
| WBStrain00036208 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (30) | |||||||||
| Paralog | WBGene00016197 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WBGene00006826 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | pin-2 encodes a LIM domain-containing protein that, along with UNC-97, comprises the two C. elegans members of the PINCH family of predicted adapter proteins; based upon its similarity to Drosophila and vertebrate members of the PINCH family, PIN-2 is predicted to play a role in regulation of cell morphology, motility, and survival, but as loss of pin-2 via large-scale RNAi results in no obvious defects, the precise role of PIN-2 in C. elegans development and/or behavior is not yet known; a PIN-2::GFP fusion protein is first expressed in embryos just prior to hatching and in early larvae is seen in several neurons, including the PVT neuron, and in intestinal cells; during postembryonic development, neuronal expression continues, whereas intestinal expression gradually declines; PIN-2 localizes to the cytoplasm and to the nucleus, and in neurons, is seen in axonal processes and varicosities. | Paper_evidence | WBPaper00003361 | |||||
| WBPaper00005633 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Oct 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including cell-cell junction organization; positive regulation of integrin-mediated signaling pathway; and positive regulation of substrate adhesion-dependent cell spreading. Located in cytoplasm; nucleus; and varicosity. Expressed in PVT. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F07C6.1a | |||||||
| F07C6.1b | |||||||||
| Corresponding_CDS_history | F07C6.1:wp230 | ||||||||
| Corresponding_transcript | F07C6.1a.1 | ||||||||
| F07C6.1b.1 | |||||||||
| Other_sequence | ACC16648_1 | ||||||||
| EX534779.1 | |||||||||
| Associated_feature | WBsf646488 | ||||||||
| WBsf998230 | |||||||||
| WBsf998231 | |||||||||
| WBsf998232 | |||||||||
| WBsf998233 | |||||||||
| WBsf1018433 | |||||||||
| WBsf1018434 | |||||||||
| WBsf229330 | |||||||||
| Transcription_factor | WBTranscriptionFactor000364 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00043898 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr1012637 | ||||||||
| Expr1031932 | |||||||||
| Expr1147872 | |||||||||
| Expr2014929 | |||||||||
| Expr2033164 | |||||||||
| Marker44 | |||||||||
| Drives_construct | WBCnstr00001579 | ||||||||
| WBCnstr00035734 | |||||||||
| Construct_product | WBCnstr00035734 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (111) | |||||||||
| Interaction | WBInteraction000237422 | ||||||||
| WBInteraction000239571 | |||||||||
| WBInteraction000392393 | |||||||||
| WBInteraction000413109 | |||||||||
| WBInteraction000443625 | |||||||||
| WBInteraction000446671 | |||||||||
| WBInteraction000450879 | |||||||||
| Map_info | Map | IV | Position | 6.34352 | Error | 0.010516 | |||
| Positive | Positive_clone | F07C6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5104 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003361 | ||||||||
| WBPaper00013448 | |||||||||
| WBPaper00015518 | |||||||||
| WBPaper00027309 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
