WormBase Tree Display for Gene: WBGene00004046
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| WBGene00004046 | SMap | S_parent | Sequence | F45E4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | plp-1 | Person_evidence | WBPerson539 | |||||
| Sequence_name | F45E4.2 | ||||||||
| Molecular_name | F45E4.2 | ||||||||
| F45E4.2.1 | |||||||||
| CE10494 | |||||||||
| Other_name | CELE_F45E4.2 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | plp-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | plp | ||||||||
| Allele (21) | |||||||||
| Legacy_information | [Joel H. Rothman] Similar to the transcriptional activator pur-alpha (pur-alpha like protein) | ||||||||
| Strain | WBStrain00002953 | ||||||||
| WBStrain00032403 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00008976 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | plp-1 encodes a protein containing three PUR repeats that has similarity to the mammalian transcription factor pur alpha; plp-1 is required for embryonic development, development of the pharynx, and formation of the intestine; PLP-1 interacts with double-stranded DNA and specifically, with a Lef-1 binding site within the end-1 promoter; PLP-1 DNA binding is regulated by phosphorylation. | Paper_evidence | WBPaper00006241 | |||||
| WBPaper00032400 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 17 Jun 2011 00:00:00 | ||||||||
| Automated_description | Enables double-stranded telomeric DNA binding activity. Involved in germ cell development and regulation of locomotion. Located in P granule and nucleus. Expressed in several structures, including Caa; Cpa; Psub4; oocyte; and somatic cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 31. Is an ortholog of human PURB (purine rich element binding protein B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070061 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9701) | ||||
| Molecular_info | Corresponding_CDS | F45E4.2 | |||||||
| Corresponding_transcript | F45E4.2.1 | ||||||||
| Other_sequence (78) | |||||||||
| Associated_feature | WBsf646102 | ||||||||
| WBsf660319 | |||||||||
| WBsf978529 | |||||||||
| WBsf981787 | |||||||||
| WBsf228556 | |||||||||
| WBsf228557 | |||||||||
| WBsf228558 | |||||||||
| Gene_product_binds | WBsf038804 | ||||||||
| Transcription_factor | WBTranscriptionFactor000127 | ||||||||
| Experimental_info | RNAi_result (41) | ||||||||
| Expr_pattern (14) | |||||||||
| Drives_construct | WBCnstr00003459 | ||||||||
| WBCnstr00011658 | |||||||||
| WBCnstr00035723 | |||||||||
| WBCnstr00042523 | |||||||||
| Construct_product | WBCnstr00011658 | ||||||||
| WBCnstr00035723 | |||||||||
| WBCnstr00042523 | |||||||||
| Regulate_expr_cluster | WBPaper00060526:plp-1(ok2155)_downregulated | ||||||||
| WBPaper00060526:plp-1(ok2155)_upregulated | |||||||||
| Antibody | WBAntibody00001881 | ||||||||
| WBAntibody00002923 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (155) | |||||||||
| Interaction (72) | |||||||||
| Map_info | Map | IV | Position | 3.36566 | Error | 0.000571 | |||
| Positive | Positive_clone | F45E4 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Sequence connection from [Rothman JH] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
