WormBase Tree Display for Gene: WBGene00004276
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| WBGene00004276 | SMap | S_parent | Sequence | K09A9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rab-14 | Person_evidence | WBPerson451 | |||||
| Sequence_name | K09A9.2 | ||||||||
| Molecular_name | K09A9.2 | ||||||||
| K09A9.2.1 | |||||||||
| CE11974 | |||||||||
| K09A9.2.2 | |||||||||
| Other_name | CELE_K09A9.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | rab-14 | ||||||||
| DB_info | Database | AceView | gene | XQ224 | |||||
| WormQTL | gene | WBGene00004276 | |||||||
| WormFlux | gene | WBGene00004276 | |||||||
| NDB | locus_tag | CELE_K09A9.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004276|UniProtKB=Q93874 | |||||||
| family | PTHR24073 | ||||||||
| NCBI | gene | 181649 | |||||||
| RefSeq | protein | NM_078171.5 | |||||||
| TrEMBL | UniProtAcc | Q93874 | |||||||
| UniProt_GCRP | UniProtAcc | Q93874 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rab | ||||||||
| Allele (44) | |||||||||
| Strain | WBStrain00001551 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (35) | |||||||||
| Paralog (32) | |||||||||
| Structured_description | Concise_description | rab-14 encodes a member of the Rab GTPase family; rab-14 activity is required in engulfing cells for regulation of phagosome maturation during apoptotic cell degradation, particularly for the steps of lysosome recruitment to phagosomes and phagosome acidification; rab-14 functions redundantly with unc-108, downstream of rab-5, and upstream of rab-7 to regulate apoptotic cell clearance; a RAB-14::GFP fusion protein is ubiquitously expressed beginning at the 100-cell stage of embryogenesis and continuing through adulthood; RAB-14::GFP localizes to vesicular structures and phagosomes; murine RAB14, when expressed in C. elegans, can rescue the cell corpse removal defects of rab-14 mutant animals. | Paper_evidence | WBPaper00037661 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 18 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activity. Involved in phagolysosome assembly involved in apoptotic cell clearance and phagosome acidification involved in apoptotic cell clearance. Located in early endosome; phagocytic vesicle; and trans-Golgi network. Expressed in gonadal sheath cell; hypodermis; intestine; and pharyngeal muscle cell. Is an ortholog of human RAB14 (RAB14, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K09A9.2 | |||||||
| Corresponding_transcript | K09A9.2.1 | ||||||||
| K09A9.2.2 | |||||||||
| Other_sequence (45) | |||||||||
| Associated_feature | WBsf654664 | ||||||||
| WBsf655623 | |||||||||
| WBsf671388 | |||||||||
| WBsf1008278 | |||||||||
| WBsf1008279 | |||||||||
| WBsf1008280 | |||||||||
| WBsf1024621 | |||||||||
| WBsf1024622 | |||||||||
| WBsf238339 | |||||||||
| WBsf238340 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00101867 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00083370 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107743 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033384 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091943 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016864 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00050365 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107744 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00097926 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114657 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram128 | ||||||||
| Expr9133 | |||||||||
| Expr1018432 | |||||||||
| Expr1032114 | |||||||||
| Expr1154070 | |||||||||
| Expr2015216 | |||||||||
| Expr2033450 | |||||||||
| Drives_construct | WBCnstr00002393 | ||||||||
| WBCnstr00007540 | |||||||||
| WBCnstr00007541 | |||||||||
| WBCnstr00007544 | |||||||||
| WBCnstr00007547 | |||||||||
| WBCnstr00007561 | |||||||||
| WBCnstr00007562 | |||||||||
| WBCnstr00035593 | |||||||||
| Construct_product (13) | |||||||||
| Antibody | WBAntibody00002209 | ||||||||
| Microarray_results (32) | |||||||||
| Expression_cluster (147) | |||||||||
| Interaction (12) | |||||||||
| Map_info | Map | X | Position | 22.927 | Error | 0.002443 | |||
| Positive | Positive_clone | K09A9 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4383 | |||||||
| 4620 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
