WormBase Tree Display for Gene: WBGene00004296
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| WBGene00004296 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | T04H1 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | rad-50 | |||||||
| Sequence_name | T04H1.4 | ||||||||
| Molecular_name | T04H1.4a | ||||||||
| T04H1.4a.1 | |||||||||
| CE21149 | |||||||||
| T04H1.4b | |||||||||
| CE41010 | |||||||||
| T04H1.4b.1 | |||||||||
| Other_name | RAD50 | Accession_evidence | EMBL | Z75312 | |||||
| CELE_T04H1.4 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | rad-50 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rad | ||||||||
| Allele (77) | |||||||||
| Strain | WBStrain00000283 | ||||||||
| WBStrain00000294 | |||||||||
| WBStrain00034801 | |||||||||
| WBStrain00034804 | |||||||||
| WBStrain00034810 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (30) | |||||||||
| Contained_in_operon | CEOP5336 | ||||||||
| Ortholog (46) | |||||||||
| Structured_description | Concise_description | rad-50 encodes the C. elegans ortholog of eukaryotic Rad50 and bacterial SbcC; RAD-50 is predicted to function, in a complex with MRE-11 and COM-1, in homology-mediated double-strand break (DSB) repair; genetic analyses indicate that rad-50 is required for a distinct pathway of meiotic DSB repair that functions from the onset of meiotic prophase through the midpachytene/late pachytene transition. | Paper_evidence | WBPaper00031172 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable G-quadruplex DNA binding activity; double-stranded telomeric DNA binding activity; and single-stranded telomeric DNA binding activity. Predicted to be involved in chromosome organization and nucleic acid metabolic process. Predicted to be located in condensed nuclear chromosome. Predicted to be part of Mre11 complex. Human ortholog(s) of this gene implicated in invasive ductal carcinoma and transitional cell carcinoma. Is an ortholog of human RAD50 (RAD50 double strand break repair protein). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3008 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9816) | ||||
| DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9816) | ||||||
| Molecular_info | Corresponding_CDS | T04H1.4a | |||||||
| T04H1.4b | |||||||||
| Corresponding_transcript | T04H1.4a.1 | ||||||||
| T04H1.4b.1 | |||||||||
| Other_sequence (37) | |||||||||
| Associated_feature | WBsf647351 | ||||||||
| WBsf661875 | |||||||||
| WBsf1001543 | |||||||||
| WBsf1001544 | |||||||||
| WBsf1020546 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr1015956 | ||||||||
| Expr1032122 | |||||||||
| Expr1156042 | |||||||||
| Expr1200235 | |||||||||
| Expr1200237 | |||||||||
| Expr1200240 | |||||||||
| Expr2015240 | |||||||||
| Expr2033474 | |||||||||
| Drives_construct | WBCnstr00035584 | ||||||||
| Construct_product | WBCnstr00035584 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (165) | |||||||||
| Interaction (185) | |||||||||
| Map_info | Map | V | Position | 3.91614 | Error | 0.007399 | |||
| Positive | Positive_clone | T04H1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5624 | |||||||
| 5284 | |||||||||
| 5483 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (24) | |||||||||
| Remark | Sequence connection from [Boulton S, Vidal M] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
