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WormBase Tree Display for Gene: WBGene00004307

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Name Class

WBGene00004307EvidenceAuthor_evidenceZwartkruis F
SMapS_parentSequenceC27B7
IdentityVersion1
NameCGC_namerap-1Person_evidenceWBPerson490
Sequence_nameC27B7.8
Molecular_nameC27B7.8
C27B7.8.1
CE03037
Other_namerrp-1Author_evidenceZwartkruis F
CELE_C27B7.8Accession_evidenceNDBBX284604
Public_namerap-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrap
Allele (45)
StrainWBStrain00007655
WBStrain00007656
WBStrain00035168
WBStrain00024306
WBStrain00051648
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (48)
Paralog (14)
Structured_descriptionConcise_descriptionrap-1 encodes a member of the Ras superfamily of small GTPases; the activated protein interacts with W05B10.4 and T14G10.2 in yeast two-hybrid assays and rap-1 is expressed in some neurons in the head and tail, the rectal epithelial cells, body muscle, hypodermis, and in the somatic cells of the gonad.Paper_evidenceWBPaper00011383
WBPaper00011386
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in collagen and cuticulin-based cuticle development and epidermis development. Predicted to be located in plasma membrane. Expressed in several structures, including germ line; gonad; and neurons. Is an ortholog of human RAP1A (RAP1A, member of RAS oncogene family) and RAP1B (RAP1B, member of RAS oncogene family).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1588Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9857)
Molecular_infoCorresponding_CDSC27B7.8
Corresponding_transcriptC27B7.8.1
Other_sequence (46)
Associated_feature (15)
Experimental_infoRNAi_result (16)
Expr_patternExpr5350
Expr12382
Expr13836
Expr13938
Expr1026296
Expr1032132
Expr1145365
Expr2015255
Expr2033489
Drives_constructWBCnstr00000155
WBCnstr00004047
WBCnstr00004967
WBCnstr00004968
WBCnstr00035575
WBCnstr00040194
Construct_productWBCnstr00000155
WBCnstr00004967
WBCnstr00004968
WBCnstr00035575
Microarray_results (24)
Expression_cluster (120)
Interaction (121)
Map_infoMapIVPosition3.99974Error2e-05
PositivePositive_cloneC27B7Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (23)
RemarkThis rap-1 is not the same as the other_name (rap-1) of rpy-1 (C18H9.7)CGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene