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WormBase Tree Display for Gene: WBGene00004344

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Name Class

WBGene00004344SMapS_parentSequenceC05B5
IdentityVersion1
NameCGC_namergs-1Person_evidenceWBPerson330
Sequence_nameC05B5.7
Molecular_nameC05B5.7a
C05B5.7a.1
CE27794
C05B5.7b
CE44351
C05B5.7a.2
C05B5.7b.1
Other_nameCELE_C05B5.7Accession_evidenceNDBBX284603
Public_namergs-1
DB_infoDatabaseAceViewgene3L104
WormQTLgeneWBGene00004344
WormFluxgeneWBGene00004344
NDBlocus_tagCELE_C05B5.7
PanthergeneCAEEL|WormBase=WBGene00004344|UniProtKB=P34295
familyPTHR10845
NCBIgene176415
RefSeqproteinNM_001268127.3
NM_001382973.1
SwissProtUniProtAccP34295
TrEMBLUniProtAccD1MN65
UniProt_GCRPUniProtAccP34295
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrgs
Allele (51)
StrainWBStrain00002110
WBStrain00002015
WBStrain00026359
RNASeq_FPKM (74)
GO_annotation00007268
00041408
00041409
00041410
00041411
00041412
00041413
00041414
Ortholog (40)
Paralog (12)
Structured_descriptionConcise_descriptionrgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.Paper_evidenceWBPaper00004281
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables GTPase activator activity. Involved in chemosensory behavior and sensory perception of bitter taste. Expressed in head; neurons; and tail. Is an ortholog of human RGS19 (regulator of G protein signaling 19).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC05B5.7a
C05B5.7b
Corresponding_CDS_historyC05B5.7:wp52
Corresponding_transcriptC05B5.7a.1
C05B5.7a.2
C05B5.7b.1
Other_sequenceAF220159
FG347523.1
HBC08155_1
Hbac_isotig02240
DN152756.1
FG619603.1
FG619770.1
EE724204.1
JI476597.1
Associated_featureWBsf651432
WBsf993883
WBsf993884
WBsf993885
WBsf1015718
WBsf1015719
Experimental_infoRNAi_resultWBRNAi00010174Inferred_automaticallyRNAi_primary
WBRNAi00039692Inferred_automaticallyRNAi_primary
WBRNAi00006271Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00002798
WBCnstr00004421
WBCnstr00004865
WBCnstr00010048
WBCnstr00020145
Construct_productWBCnstr00004865
WBCnstr00010048
AntibodyWBAntibody00001585
Microarray_results (21)
Expression_clusterWBPaper00029359_1280
WBPaper00029359_1304
WBPaper00029359_1444
WBPaper00029359_1497
WBPaper00029359_1504
WBPaper00029359_1604
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037682:sma-2_upregulated
WBPaper00037946:LIN-39_interacting
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:A-class-motor-neurons_larva_enriched
WBPaper00037950:all-neurons_CoreEnriched
WBPaper00037950:all-neurons_embryo_enriched
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_larva_enriched
WBPaper00037950:AVA-neuron_embryo_enriched
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_embryo_enriched
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:BAG-neuron_embryo_enriched
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_embryo_enriched
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_embryo_enriched
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_larva_enriched
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00040209:B.thuringiensis_upregulated_MY15
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Spermatogenic
WBPaper00046805:csr-1(RNAi)_downregulated_Set1
WBPaper00046805:csr-1(RNAi)_downregulated_Set2
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049001:EVN_enriched
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050496:RID_enriched
WBPaper00050496:unc-39(hp701)_regulated
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053599:female_vs_male_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:Metformin_upregulated
WBPaper00055565:AVK_enriched
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056161:male_enriched_siRNA
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056619:CEPsh_enriched
WBPaper00056826:SGP_biased
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058691:cfp-1(tm6369)_downregulated
WBPaper00058691:set-2(bn129)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00058969:RIS_enriched
WBPaper00059027:neuron-synapses_depleted
WBPaper00059471:EGL-43_interacting
WBPaper00059605:mut-16(pk710)_downregulated
WBPaper00059605:simr-1(cmp36)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059763:neuron_expressed
WBPaper00060526:plp-1(ok2155)_downregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061340:ABarpaaa_lineage
WBPaper00061340:DVC
WBPaper00061340:I5
WBPaper00061340:Neuroblast_IL1_IL2
WBPaper00061340:Neuroblast_PVC_LUA
WBPaper00061340:OLL_parent
WBPaper00061340:Parents_of_U_F_B_DVA
WBPaper00061340:PVP
WBPaper00061340:RID_parent
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061527:sol-1-jnk-1_18695
WBPaper00061527:syd-1_2945-unc-41_2170
WBPaper00061651:PVW_enriched
WBPaper00061995:mter-4(syb3662syb3403)_downregulated
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064502:spe-44(fx110)_downregulated
WBPaper00064871:hypoxia_downregulated_F1
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065835:Day5_vs_Day1_upregulated
WBPaper00065835:Day11_vs_Day1_upregulated
WBPaper00065841:68_0
WBPaper00065841:123_0
WBPaper00065841:128_0
WBPaper00066085:sin-3(tm1276)_upregulated
cgc4489_group_13
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Enriched_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00030839:Embryo_A_Class
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030839:Larval_A_Class
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_depleted
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031252:AIN-2_IP_enriched
WBPaper00031532:Larva_Pan_Neuronal_Enriched
WBPaper00032948:StarveUp2
WBPaper00035084:embryo_enriched_AIN-2_IP
WBPaper00036123:Atrazine_regulated
WBPaper00036286:Pattern_F
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00041174:genotypic
WBPaper00041174:genotypic_prime
WBPaper00041939:control_vs_EtBr-exposed_24h
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00042548:miRISC_enriched
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045673:colistin_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00048637:lin-35(n745)_starvation_downregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00057098:SiO2-nanoparticles_upregulated
Interaction (20)
Map_infoMapIIIPosition1.53481Error0.012126
PositivePositive_cloneC05B5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4633
5300
Pseudo_map_position
Reference (14)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene